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  3. COLIGAN TABLET

COLIGAN TABLET, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

DICYCLOMINE-20MG + MEFENAMIC ACID-500MG

Manufacturer/Marketer :

Fourrts India Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About COLIGAN TABLET

COLIGAN TABLET is a combination medicine used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. Colic is a form of pain that starts and stops abruptly.

COLIGAN TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduces mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

You are advised to take COLIGAN TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, COLIGAN TABLET may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive with caution. COLIGAN TABLET is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of COLIGAN TABLET

Abdominal pain, dysmenorrhea (period pain), colicky pain

Directions for Use

Take COLIGAN TABLET with food to prevent stomach upset. Swallow COLIGAN TABLET as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

COLIGAN TABLET is a combination of two drugs, namely: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take COLIGAN TABLET if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive only if you are alert. COLIGAN TABLET should not be given to children as safety has not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking COLIGAN TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with COLIGAN TABLET unless prescribed. 

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Coligan Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Coligan Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Pramlintide with Coligan Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Coligan Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium chloride
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Coligan Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Coligan Tablet:
Taking Coligan Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Coligan Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Mefenamic acidSirolimus
Severe
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Sirolimus can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Coligan Tablet with Sirolimus together can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCabozantinib
Severe
How does the drug interact with Coligan Tablet:
Using cabozantinib together with Coligan Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Coligan Tablet and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.
Mefenamic acidPiroxicam
Severe
How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Piroxicam can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Coligan Tablet with Piroxicam together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidRivaroxaban
Severe
How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Rivaroxaban can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Coligan Tablet with Rivaroxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCidofovir
Severe
How does the drug interact with Coligan Tablet:
Coadministration of cidofovir with Coligan Tablet can increase the risk of kidney problems.

How to manage the interaction:
Although taking Coligan Tablet and cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS

COLIGAN TABLET Substitute

Substitutes safety advice

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

COLIGAN TABLET contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of COLIGAN TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

COLIGAN TABLET is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.

Dry mouth could be a side-effect of COLIGAN TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

COLIGAN TABLET should not be taken for more than 7days. Do not take COLIGAN TABLET for longer durations as it might increase the risk of heart problems and stomach bleeding.

COLIGAN TABLET is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take COLIGAN TABLET only as prescribed, and do not overdose.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • FUROSEMIDE
  • LITHIUM
  • QUINIDINE
  • PHENOTHIAZINE
  • METHOTREXATE
  • WARFARIN
  • CLOPIDOGREL
  • DIGOXIN
  • GLIMEPIRIDE
  • GLICLAZIDE
  • GLIBENCLAMIDE
  • GENTAMICIN
  • TOBRAMYCIN
  • AMIKACIN
  • CYCLOSPORINE
  • MIFEPRESTONE
  • TACROLIMUS
  • ZIDOVUDINE
  • METOCLOPRAMIDE

Special Advise

  • COLIGAN TABLET may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking COLIGAN TABLET.
  • COLIGAN TABLET may cause a false-positive reaction for urinary bile test. Inform the person doing the test that you are taking COLIGAN TABLET.

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders, and obstruction/blockage.

Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Menstrual cramps cause throbbing, aching pain in the lower belly that occurs before or during the periods.

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