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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Combihale FF 250 Redicaps

Combihale FF 250 Redicaps is a combination medication primarily used to treat and prevent asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Combihale FF 250 Redicaps is a combination of two medicines, namely: Formoterol fumarate (bronchodilator) and Fluticasone propionate (corticosteroids). Formoterol fumarate is a long-acting beta-agonist that relaxes the muscles in the airways and increases airflow to the lungs. Thereby making breathing easier by widening the airways. Fluticasone propionate acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Thereby, it provides relief from sneezing, runny or blocked nose and sinus discomfort. 

Use Combihale FF 250 Redicaps as advised by the doctor. Your doctor will decide the dose and duration based on your medical condition. The common side effects of Combihale FF 250 Redicaps include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, tiredness and noisy breathing. Most of these side effects of Combihale FF 250 Redicaps do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not use Combihale FF 250 Redicaps to treat sudden severe asthma symptoms or as a rescue inhaler. Please check with your doctor if you are pregnant, currently breastfeeding or taking any other prescribed or non-prescribed medicines. Combihale FF 250 Redicaps is not recommended for children below five years of age. If you experience severe difficulty in breathing, please consult a doctor immediately so that alternative medicine may be prescribed. Regular monitoring of potassium levels is recommended while taking Combihale FF 250 Redicaps as it may cause low potassium levels in the blood.

Uses of Combihale FF 250 Redicaps

Asthma, Chronic Obstructive Pulmonary Disease (COPD)

Directions for Use

Inhaler: Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.Rotacap: Place the rotahaler between your teeth and seal it with your lips. Breathe with your mouth deeply while you press the rotahaler. Remove the device and breathe out normally.Autohaler: Autohaler is a breath-activated device that releases the medication when you inhale. Shake the autohaler well before using it. Hold it upright and push the lever up. Place the mouthpiece in your mouth and seal your lips around it. Breathe in slowly and deeply to release the medication from the device. Hold your breath for 10 seconds and breathe out normally. Push the lever down and replace the cap.Capsule: It is for inhalation use only; do not swallow. The capsule form contains powdered medication, which is to be inserted into the inhaling device/inhaler. It releases the medicine when you breathe deeply with your mouth through the inhaler.Rotadisk: Rotadisk is a silver-coloured aluminium foil disk that contains four blisters to place the medication. The medicine is to be inhaled through the mouth from the Rotadisk using a device called Diskhaler.

Medicinal Benefits

Combihale FF 250 Redicaps is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Combihale FF 250 Redicaps improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Combihale FF 250 Redicaps is a combination of Formoterol fumarate and Fluticasone propionate. Formoterol fumarate is a long-acting β₂ agonist and bronchodilator. It relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone propionate belongs to the class of corticosteroids. It acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Together, Combihale FF 250 Redicaps helps treat asthma and COPD.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Combihale FF 250 Redicaps , let your doctor know if you have a history of heart, liver, kidney diseases, high blood pressure, hypokalaemia (low potassium levels in the blood), aneurysm (swelling of an artery), pheochromocytoma (adrenal gland tumour), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, chickenpox or measles, immune system problem, seizure (fits), osteoporosis (weak and brittle bones) and diabetes. Combihale FF 250 Redicaps may cause hypokalemia (low potassium levels in the blood). Therefore they should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects. Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since nasal or inhaled corticosteroids like Fluticasone propionate can cause secondary infections. Combihale FF 250 Redicaps can cause a rise in blood glucose levels. Hence monitor your blood glucose levels regularly and inform your doctor if you already have diabetes before using Combihale FF 250 Redicaps . Please let your doctor know if you are pregnant or breastfeeding. Combihale FF 250 Redicaps is not recommended for children below five years of age.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Combihale FF 250 Redicaps with Mifepristone may make Combihale FF 250 Redicaps less effective as a therapy.

How to manage the interaction:
Taking Combihale FF 250 Redicaps with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Desmopressin with Combihale FF 250 Redicaps may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Combihale FF 250 Redicaps together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
FluticasoneTroleandomycin
Severe
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Troleandomycin may significantly increase the absorption of Combihale FF 250 Redicaps and tend to increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Combihale FF 250 Redicaps and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
FluticasoneAmprenavir
Severe
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Amprenavir and Combihale FF 250 Redicaps may significantly increase the absorption of Combihale FF 250 Redicaps into the blood stream.

How to manage the interaction:
Co-administration of Amprenavir and Combihale FF 250 Redicaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneSaquinavir
Severe
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Saquinavir may increase the absorption of Combihale FF 250 Redicaps into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Combihale FF 250 Redicaps and Saquinavir together, a doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Combihale FF 250 Redicaps with posaconazole may increase the level of Combihale FF 250 Redicaps in the blood and increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Combihale FF 250 Redicaps and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Atazanavir and Combihale FF 250 Redicaps may significantly increase the absorption of Combihale FF 250 Redicaps into the bloodstream.

How to manage the interaction:
Co-administration of Atazanavir and Combihale FF 250 Redicaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneBoceprevir
Severe
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Boceprevir with Combihale FF 250 Redicaps may significantly increase the absorption of Combihale FF 250 Redicaps into the bloodstream.

How to manage the interaction:
Co-administration of Boceprevir and Combihale FF 250 Redicaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneDinutuximab
Severe
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Dinutuximab and Combihale FF 250 Redicaps may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Combihale FF 250 Redicaps can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combihale FF 250 Redicaps:
Co-administration of Combihale FF 250 Redicaps with Voriconazole may increase the absorption of Combihale FF 250 Redicaps into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although Combihale FF 250 Redicaps and Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medicines, herbal or vitamin supplements without informing your pharmacist or doctor when you take Combihale FF 250 Redicaps .
  • Know your triggers like allergens, such as pollen, dust and food items that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Combihale FF 250 Redicaps consists of Formoterol fumarate (bronchodilator) and Fluticasone propionate (Fluticasone). Formoterol fumarate relaxes the muscles in the airways and increases airflow to the lungs. Fluticasone propionate acts by blocking prostaglandin's production (chemical messengers) that cause inflammation (swelling) of the airways. Together, Combihale FF 250 Redicaps helps treat asthma and COPD.

Combihale FF 250 Redicaps may raise blood glucose levels. Therefore, please consult your doctor if you are diabetic. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.

Combihale FF 250 Redicaps may decrease the potassium levels in your body. Please consult your doctor before taking Combihale FF 250 Redicaps since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Combihale FF 250 Redicaps may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Combihale FF 250 Redicaps to experience this side effect. However, to avoid dry mouth, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. If the condition persists or worsens, please consult a doctor.

Combihale FF 250 Redicaps is not recommended for use when taking Sotalol or vice versa. Sotalol and Combihale FF 250 Redicaps have opposing effects on the body. Sotalol may also trigger asthma attacks or worsen breathing problems by narrowing the airways. Please consult your doctor before using other medicines with Combihale FF 250 Redicaps .

No, Combihale FF 250 Redicaps is not used for sudden breathing problems; your doctor may suggest a rescue inhaler for sudden breathing problems.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • BUDESONIDE
  • MOMETASONE
  • BECLOMETHASONE
  • VILANTEROL
  • SALMETEROL
  • ALBUTEROL
  • IPRATROPIUM
  • SOTALOL
  • METOPROLOL

Special Advise

  •  
  • It is advised to undergo a blood examination to check your potassium levels since Combihale FF 250 Redicaps can cause low potassium levels in the blood (hypokalaemia).
  • Regularly monitor your blood sugar levels while using Combihale FF 250 Redicaps since bronchodilators like Formoterol fumarate can cause low blood glucose levels.
  • Consult your diabetologist if you have diabetes before using Combihale FF 250 Redicaps so that your insulin or other diabetic medication doses can be adjusted accordingly to maintain your blood sugar levels.
  •  

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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