apollo
0
Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Apr-24

Therapeutic Class

ANTIBIOTIC COMBINATION

Country of origin

India
Other Info - COM0455

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Combisaf Tablet 1's consists of three antibiotic drugs, namely Azithromycin, Fluconazole, and Secnidazole. These are effective against various infection-causing microbes by inhibiting their growth. Thus Combisaf Tablet 1's helps to treat a variety of vaginal infections.
Combisaf Tablet 1's should be used with proper caution and doctor consultation if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), active infections, allergic conditions, ulcers or blisters, and urination problems.
Do not stop using Combisaf Tablet 1's even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.
It is not advised to take any antacids containing magnesium or aluminium for up to two hours after using Combisaf Tablet 1's since it may interfere with the absorption of Combisaf Tablet 1's.
Keep Combisaf Tablet 1's in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Unsafe

Alcohol consumption, along with Combisaf Tablet 1's, may cause flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. It is advised to avoid alcohol intake during the course with Combisaf Tablet 1's.

bannner image

Pregnancy

Caution

It is better to avoid Combisaf Tablet 1's during the first trimester of pregnancy. Please consult your doctor if you are planning to conceive or already pregnant before starting Combisaf Tablet 1's.

bannner image

Breast Feeding

Caution

Combisaf Tablet 1's should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

bannner image

Driving

Caution

Combisaf Tablet 1's may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are nor mentally alert.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Combisaf Tablet 1's. Your doctor may adjust the dosage.

bannner image

Kidney

Caution

Caution is recommended if you have any history of kidney diseases before taking Combisaf Tablet 1's. Your doctor may adjust the dosage. Combisaf Tablet 1's is not recommended in case of severe renal impairment.

bannner image

Children

Unsafe

Combisaf Tablet 1's is not recommended for children below 12 years of age. Do not give this medicine to your child without medical advice.

About Combisaf Tablet 1's

Combisaf Tablet 1's belongs to the class of 'antibiotics', primarily used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Chlamydia is a sexually transmitted infection caused by bacteria. Symptoms of a vaginal infection include itching, odour and abnormal vaginal discharge.

Combisaf Tablet 1's comprises three medicines: Azithromycin (antibiotic), Fluconazole (antifungal), and Secnidazole (antibiotic). Azithromycin belongs to the class of 'macrolide antibiotics'. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Fluconazole belongs to the class of 'azole antifungal' agents. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic that belongs to the class of 'amoebicides'. It works by stopping the growth of infection-causing bacteria.

Use Combisaf Tablet 1's as prescribed by the doctor. Common side effects of Combisaf Tablet 1's include taste changes, vomiting, headache, dizziness, stomach pain, nausea, indigestion, diarrhoea, and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to Combisaf Tablet 1's or any of its components. It is essential to tell your doctor if you use any other azole antifungal agents before using Combisaf Tablet 1's. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Pregnant and breastfeeding women should consult their doctor before starting Combisaf Tablet 1's. It is advised to avoid alcohol intake while using Combisaf Tablet 1's to prevent any undesirable effects.

Uses of Combisaf Tablet 1's

Vaginal infections, bacterial vaginosis (BV), candidiasis, and trichomoniasis. 

Medicinal Benefits Mweb

Medicinal Benefits

Combisaf Tablet 1's is used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. It comprises three medicines: Azithromycin, Fluconazole, and Secnidazole. Azithromycin is an antibiotic that works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth. Fluconazole is an antifungal drug that stops fungi growth by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic works by stopping the growth of infection-causing bacteria. It effectively treats vaginal infection (bacterial vaginosis).

Directions for Use

Take Combisaf Tablet 1's with food as prescribed by your doctor. Swallow Combisaf Tablet 1's as a whole with a glass of water, do not chew, break or crush it.

Side Effects of Combisaf Tablet 1's

  • Taste changes
  • Vomiting
  • Headache
  • Dizziness
  • Stomach pain
  • Nausea
  • Indigestion
  • Diarrhoea
  • Loss of appetite 

Drug Warnings

Please inform your doctor if you use any prescription, non-prescription medicines, including vitamin and herbal supplements before using Combisaf Tablet 1's. Do not use Combisaf Tablet 1's if you are allergic to Combisaf Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Combisaf Tablet 1's is not recommended in case of severe renal impairment. It is advised to use Combisaf Tablet 1's under your doctor's supervision if you use other azole antifungal medicines. It is better to avoid Combisaf Tablet 1's during the first trimester of pregnancy. Combisaf Tablet 1's should be used with caution and only under a doctor's advice if you are a nursing mother. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Combisaf Tablet 1's to avoid undesirable effects like flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. Do not take any antacids containing magnesium or aluminum for up to two hours after using Combisaf Tablet 1's.

Drug-Drug Interactions

verifiedApollotooltip
AceclofenacAtenolol
Severe
ParacetamolValdecoxib
Severe

Drug-Drug Interactions

Login/Sign Up

AceclofenacAtenolol
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Atenolol with Combisaf Tablet 1's could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Combisaf Tablet 1's, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Combisaf Tablet 1's and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Combisaf Tablet 1's and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Combisaf Tablet 1's and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Combisaf Tablet 1's and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Mipomersen with Combisaf Tablet 1's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Combisaf Tablet 1's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Lomitapide and Combisaf Tablet 1's may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Combisaf Tablet 1's and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolOxazepam
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Combisaf Tablet 1's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Combisaf Tablet 1's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of ketamine and Combisaf Tablet 1's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Combisaf Tablet 1's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Teriflunomide with Combisaf Tablet 1's may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Combisaf Tablet 1's with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Combisaf Tablet 1's:
Co-administration of Combisaf Tablet 1's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Combisaf Tablet 1's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • DIGOXIN
  • TRIAZOLAM
  • CYCLOSPORINE
  • TACROLIMUS
  • CARBAMAZEPINE
  • PHENYTOIN
  • RIFAMPICIN
  • RIFABUTIN
  • THEOPHYLLINE
  • ASTEMIZOLE

Habit Forming

No

Special Advise

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.
  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.

Combisaf Tablet 1's Substitute

Substitutes safety advice
  • Isp Kit Tablet 1's

    by AYUR

    135.00per tablet
  • Fas 3 Kit

    by Others

    31.27per tablet
  • LGI-3 Kit Tablet 4's

    by Others

    28.13per tablet
  • BTC+Kit Combikit Tablet 4's

    by Others

    28.57per tablet
  • Shie Kit Tablet 4's

    by Others

    28.80per tablet
winter care Floating Button
winter care Floating Button