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  3. Cotrim 5Ml Inj

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Zyphar's Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIBIOTIC COMBINATION

Country of origin

India

Manufacturer/Marketer address

102/103, Park Plaza, Opp. Kamla Nehru Park, Off. Bhandarkar Road, Pune - 411004, Maharashtra (India)
Other Info - COT0162

Author Details

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FAQs

Cotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Cotrim 5Ml Inj kills the bacteria and stops their growth. Thus, it helps to treat bacterial infections.

Cotrim 5Ml Inj causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Cotrim 5Ml Inj. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, inform your doctor. Do not take anti-diarrheal medicine on your own.

Cotrim 5Ml Inj may affect certain laboratory test results. Inform the lab technician that you are taking Cotrim 5Ml Inj.

Cotrim 5Ml Inj may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Cotrim 5Ml Inj.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while taking Cotrim 5Ml Inj to prevent unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor before taking Cotrim 5Ml Inj if you are pregnant. Cotrim 5Ml Inj may cause fetal harm. Your doctor will prescribe Cotrim 5Ml Inj only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Cotrim 5Ml Inj as it may cause bilirubin displacement and kernicterus (brain damage resulting from high levels of bilirubin in the blood). Please consult your doctor if you have any concerns.

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Driving

Caution

It is unknown whether Cotrim 5Ml Inj affects your ability to drive and operate machinery. Drive only if you are physically stable and mentally focused.

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Liver

Caution

Please inform your doctor before taking Cotrim 5Ml Inj if you have liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

Please inform your doctor before taking Cotrim 5Ml Inj if you have kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Cotrim 5Ml Inj is not recommended for infants below 6 weeks.

About Cotrim 5Ml Inj

Cotrim 5Ml Inj belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Cotrim 5Ml Inj does not work against infections caused by the virus, including cold and flu. 

Cotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Cotrim 5Ml Inj stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Cotrim 5Ml Inj will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Cotrim 5Ml Inj, please inform your doctor if you have any allergy (against any antibiotic), severe kidney or liver problems, porphyria (blood disorder), or blood problems which may cause bleeding or bruising. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Cotrim 5Ml Inj is not recommended for infants below 6 weeks. Keep your doctor informed about your medical history and your ongoing medications to rule out any side effects/interactions.

Uses of Cotrim 5Ml Inj

Bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

Cotrim 5Ml Inj belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Cotrim 5Ml Inj is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Cotrim 5Ml Inj kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Cotrim 5Ml Inj is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria.

Directions for Use

Cotrim 5Ml Inj is administered by a healthcare professional; do not self-administer.

Side Effects of Cotrim 5Ml Inj

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

 

Drug Warnings

Do not take Cotrim 5Ml Inj if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (a rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Cotrim 5Ml Inj if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Cotrim 5Ml Inj:
Taking Cotrim 5Ml Inj with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Cotrim 5Ml Inj and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cotrim 5Ml Inj:
Taking Bupivacaine and Cotrim 5Ml Inj may cause methemoglobinemia, (blood disorder that affects how red blood cells deliver oxygen throughout the body).

How to manage the interaction:
Although there is an interaction between bupivacaine and Cotrim 5Ml Inj, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cotrim 5Ml Inj:
Taking Potassium chloride with Cotrim 5Ml Inj may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood.).

How to manage the interaction:
Although there is a possible interaction between Cotrim 5Ml Inj and Potassium chloride, you can take these medicines together if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cotrim 5Ml Inj:
Taking Cotrim 5Ml Inj with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between telmisartan and Cotrim 5Ml Inj, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, and a weak pulse. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Cotrim 5Ml Inj:
When amiloride is taken with Cotrim 5Ml Inj it may raise potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm).

How to manage the interaction:
Although there is an interaction between amiloride and Cotrim 5Ml Inj, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cotrim 5Ml Inj:
Co-administration of Cotrim 5Ml Inj with phenytoin may increase the blood levels and effects of phenytoin.

How to manage the interaction:
Although there is an interaction between Cotrim 5Ml Inj and phenytoin but can be taken together if prescribed by doctor. However, if you experience nausea, vomiting, twitching eye movements, blurred vision, difficult to speak, loss of balance or coordination, tremors (shaking of hands legs), and confusion contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
How does the drug interact with Cotrim 5Ml Inj:
Taking spironolactone with Cotrim 5Ml Inj may increase potassium levels in the blood.

How to manage the interaction:
Although taking spironolactone and Cotrim 5Ml Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
How does the drug interact with Cotrim 5Ml Inj:
Coadministration of Azilsartan medoxomil with Cotrim 5Ml Inj may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Cotrim 5Ml Inj, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Cotrim 5Ml Inj:
Taking Lisinopril with Cotrim 5Ml Inj may increase potassium levels in the blood.

How to manage the interaction:
Although taking Cotrim 5Ml Inj and Lisinopril together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
How does the drug interact with Cotrim 5Ml Inj:
Taking Cotrim 5Ml Inj with Levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levobupivacaine and Cotrim 5Ml Inj, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENYTOIN
  • DIGOXIN
  • ZIDOVUDINE
  • PROCAINAMIDE

Habit Forming

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Special Advise

  • Cotrim 5Ml Inj may affect certain laboratory test results such as blood tests. Inform the lab technician that you are taking Cotrim 5Ml Inj. 
  • Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed Cotrim 5Ml Inj for a longer duration, to know if the medicine is working properly.

 

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

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