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It is suggested to store the Cresp 25 Injection in the refrigerator and protect it from light. However, a person should not freeze it.
It is advised to tell your doctor about your medical conditions like heart disease, high blood pressure, kidney disease, a stroke, heart attack, or blood clot, a seizure, a latex allergy to avoid any type of medical condition.
A person who is allergic to any chemical compound present in Cresp 25 Injection or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.
Consult your doctor before taking Cresp 25 Injection if you are pregnant or planning for pregnancy. Your doctor will prescribe Cresp 25 Injection only if the benefits outweigh the risks.
Cresp 25 Injection contains a protein "Darbepoetin alfa", which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
Alcohol
Unsafe
Avoid consumption of alcohol while taking Cresp 25 Injection as it may increase dizziness and sleepiness.
Pregnancy
Caution
Avoid taking Cresp 25 Injection if you are pregnant unless prescribed by a doctor as Cresp 25 Injection is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Consult your doctor before taking Cresp 25 Injection; your doctor will decide whether Cresp 25 Injection can be taken by breastfeeding mothers or not.
Driving
Unsafe
Cresp 25 Injection causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Cresp 25 Injection should not be given to children as the safety and efficacy have not been established.
Product Substitutes
Keep Refrigerated. Do not freeze.Prepaid payment required.
About Cresp 25 Injection
Cresp 25 Injection belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Cresp 25 Injection helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.
Cresp 25 Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Cresp 25 Injection is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Cresp 25 Injection stimulates the production of this protein in the bone marrow.
Cresp 25 Injection will be injected by the healthcare provider. Do not self-administer. The most common side effects of Cresp 25 Injection are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Cresp 25 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Cresp 25 Injection to avoid any complications. Also, mention all the other medications you are taking to affect the way Cresp 25 Injection works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Cresp 25 Injection.
Uses of Cresp 25 Injection
Medicinal Benefits
Cresp 25 Injection is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia. This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells' cancer. Cresp 25 Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells.
Directions for Use
Side Effects of Cresp 25 Injection
Drug Warnings
Cresp 25 Injection can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking Cresp 25 Injection if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take Cresp 25 Injection if you are pregnant or breastfeeding unless prescribed by the doctor. Cresp 25 Injection may affect a person's ability to drive as it may cause convulsion during initial days of treatment, so a person taking Cresp 25 Injection should avoid driving or operating any machine. Cresp 25 Injection should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with Cresp 25 Injection as it could lead to increased dizziness and sleepiness.
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