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  3. Crf-X Syrup 100 ml

Crf-X Syrup 100 ml, Pack of 1 Syrup
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

BROMHEXINE-4MG + GUAIFENESIN-50MG + MENTHOL-2.5MG + TERBUTALINE-1.25MG

Manufacturer/Marketer :

Acme Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Crf-X Syrup

Crf-X Syrup belongs to a class of respiratory medication called ‘expectorant' primarily used to treat vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder) having a cough. It helps in dissolving hard phlegm (sputum/cough) which makes breathing difficult usually in respiratory problems like allergies, sinusitis, common cold, bronchitis, flu, etc. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.

Crf-X Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Take Crf-X Syrup as prescribed. Your doctor will recommend how often you take Crf-X Syrup based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset, and fast heartbeats. Most of these side effects of Crf-X Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Crf-X Syrup or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, it is advised to inform your doctor before taking Crf-X Syrup . Avoid taking Crf-X Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits or have a history of fits, please inform your doctor before taking Crf-X Syrup as it may increase the risk of recurrent fits. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Crf-X Syrup . If you have diabetes, fits, high blood pressure, glaucoma, cough for a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Crf-X Syrup .

Uses of Crf-X Syrup

Cough

Directions for Use

Shake the bottle well before use. Check the label for directions before using Crf-X Syrup and take it with or without food as prescribed by your doctor with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Crf-X Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Storage

Keep Crf-X Syrup out of the sight and reach of children.

Drug Warnings

If you are known to be allergic to Crf-X Syrup or any other medicines, pregnant or planning for pregnancy, it is advised to inform your doctor before taking Crf-X Syrup . Avoid taking Crf-X Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits (epilepsy) or have a history of fits, please inform your doctor before taking Crf-X Syrup as it may increase the risk of recurrent fits. If you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Crf-X Syrup .

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Crf-X Syrup Substitute

Substitutes safety advice

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:30 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Crf-X Syrup contains Guaifenesin, Bromhexine, Terbutaline and Menthol. Guaifenesin is an expectorant that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from airways. Bromhexine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in lungs, windpipe and nose. Thereby, helps to cough out easily. Terbutaline is a bronchodilator that relaxes muscles and widens the airways. Thereby, makes breathing easier. Menthol is a cooling agent that produces cooling sensation and provides relief from minor throat irritation.

Yes, Crf-X Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Crf-X Syrup to experience this side effect. Therefore, avoid driving if you feel drowsy or dizzy after taking Crf-X Syrup .

Crf-X Syrup should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Crf-X Syrup as it may increase blood sugar levels.

No, you are not recommended to take propranolol with Crf-X Syrup as it may reduce the effectiveness of both the medicines. Also, propranolol may cause narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, you are recommended to consult a doctor before using other medicines with Crf-X Syrup .

Crf-X Syrup should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if have hyperthyroidism before taking Crf-X Syrup so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Crf-X Syrup .

You are recommended to take Crf-X Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Crf-X Syrup , please consult your doctor.

No, you are not recommended to stop taking Crf-X Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Crf-X Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Crf-X Syrup , please consult your doctor.

Drug-Drug Interactions Checker List

  • PROPRANOLOL
  • EPINEPHRINE
  • FUROSEMIDE
  • PROMETHAZINE
  • OXYTOCIN
  • FORMOTEROL
  • DYPHYLLINE
  • ONDANSETRON

Special Advise

Regularly monitor blood sugar levels while taking Crf-X Syrup if you have diabetes as it may increase blood sugar levels.

Disease/Condition Glossary

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-colored, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

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