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  3. Crixan 125 Suspension 30 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CRI0006

FAQs

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

After taking antibiotics such as Crixan 125 mg Suspension, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Crixan 125 mg Suspension treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.

No, Crixan 125 mg Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.

Side effects are rare with Crixan 125 mg Suspension and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Disclaimer

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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Crixan 125 mg Suspension can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

About Crixan 125 mg Suspension

Crixan 125 mg Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

Like all medicines, Crixan 125 mg Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Crixan 125 mg Suspension unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Crixan 125 mg Suspension

Bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

Crixan 125 mg Suspension belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

Directions for Use

Oral Suspension: Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Side Effects of Crixan 125 mg Suspension

  • Headache
  • Diarrhoea
  • Being sick (vomiting)
  • Nausea (feeling sick)
  • Loss of appetite
  • Taste change
  • Bloating
  • Indigestion
  • Abdominal pain
  • Insomnia (difficulty sleeping)

Drug Warnings

Before using Crixan 125 mg Suspension, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Crixan 125 mg Suspension unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Crixan 125 mg Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Crixan 125 mg Suspension and iron supplements and antacids.

Drug-Drug Interactions

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ClarithromycinSaquinavir
Critical

Drug-Drug Interactions

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ClarithromycinSaquinavir
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Crixan 125 Suspension 30 ml is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
When Nimodipine is taken with Crixan 125 Suspension 30 ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Crixan 125 Suspension 30 ml is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crixan 125 Suspension 30 ml:
Using Lurasidone together with Crixan 125 Suspension 30 ml may result in significantly higher Lurasidone blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Crixan 125 Suspension 30 ml may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crixan 125 Suspension 30 ml:
When Cabergoline is taken with Crixan 125 Suspension 30 ml, the amount of Cabergoline in the blood can go up.

How to manage the interaction:
Taking Cabergoline with Crixan 125 Suspension 30 ml is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
ClarithromycinLomitapide
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Lomitapide is taken with Crixan 125 Suspension 30 ml, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
When Cisapride is taken with Crixan 125 Suspension 30 ml, the amount of Cisapride in the blood can go up.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Cisapride can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Quinidine is taken with Crixan 125 Suspension 30 ml, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
Combining Crixan 125 Suspension 30 ml with Pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Pimozide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
Taking Silodosin with Crixan 125 Suspension 30 ml may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Silodosin is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLARITHROMYCIN-125MGOther bacterial intestinal infections
Severe
CLARITHROMYCIN-125MGToxic liver disease
Moderate

Drug-Diseases Interactions

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CLARITHROMYCIN-125MGOther bacterial intestinal infections
Severe
How does the disease interact with Crixan 125 Suspension 30 ml:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.

How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-125MGToxic liver disease
Moderate
How does the disease interact with Crixan 125 Suspension 30 ml:
Patients on Crixan 125 Suspension 30 ml have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.

How to manage the interaction:
Caution and monitoring is advised if Crixan 125 Suspension 30 ml is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Crixan 125 Suspension 30 ml is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Crixan 125 Suspension 30 ml.
CLARITHROMYCIN-125MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Crixan 125 Suspension 30 ml:
The kidney and liver are the organs that eliminate of Crixan 125 Suspension 30 ml the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.

How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-125MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Crixan 125 Suspension 30 ml:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.

How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-125MGAbnormal results of function studies
Moderate
How does the disease interact with Crixan 125 Suspension 30 ml:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Crixan 125 Suspension 30 ml and erythromycin.

How to manage the interaction:
Crixan 125 Suspension 30 ml should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.

Drug-Drug Interactions Checker List

  • AZITHROMYCIN
  • AMOXICILLIN+CLAVULANIC ACID
  • SIMVASTATIN
  • ATORVASTATIN
  • WARFARIN
  • DIGOXIN
  • COLCHICINE
  • THEOPHYLLINE
  • BUDESONIDE/FORMOTEROL
  • CARBAMAZEPINE
  • PHENYTOIN
  • ERGOTAMINE
  • DIHYDROERGOTAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Crixan 125 mg Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Crixan 125 mg Suspension.

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