Do not take Cyldena 10 mg Injection 12.5 ml if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).