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  3. Dalimune 50mg Tablet

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rxMedicinePrescription drug

Composition :

DOLUTEGRAVIR-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIRETROVIRAL AGENTS

Country of origin

India
Other Info - DA65668

Author Details

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FAQs

Dalimune 50mg Tablet works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body to fight infection.

Antacids used to treat heartburn or indigestion, multivitamins, calcium or iron supplements may stop the absorption of Dalimune 50mg Tablet and make it less effective. Therefore, do not take antacid, multivitamins, calcium or iron supplements 6 hours before and 2 hours after taking Dalimune 50mg Tablet. However, consult the doctor before taking other medicines while on treatment with Dalimune 50mg Tablet.

Few people taking combination therapy for HIV may develop osteonecrosis. Consult the doctor if you experience symptoms of osteonecrosis, such as stiffness in the joints, joint pain or aches, and difficulty moving.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known whether Dalimune 50mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Dalimune 50mg Tablet may increase the risk of birth defects. Please consult the doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dalimune 50mg Tablet. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Caution

Dalimune 50mg Tablet may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. Please consult your doctor if you have liver problems. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Kidney

Consult your doctor

Limited information is available. Please consult your doctor if you have kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Children

Caution

Please consult the doctor if you have any concerns regarding the usage of Dalimune 50mg Tablet in children.

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Heart

Inform your doctor if you have any heart problems before using Dalimune 50mg Tablet.

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Geriatrics

Consult your doctor

Dalimune 50mg Tablet is generally safe in older adults, but they may be more prone to side effects such as tooth staining and altered taste. Please consult a doctor if you have any concerns.

About Dalimune 50mg Tablet

Dalimune 50mg Tablet belongs to a group of antiretroviral medicines called HIV integrase inhibitors indicated for the treatment of HIV infection. Dalimune 50mg Tablet does not cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Dalimune 50mg Tablet decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections.
 
Dalimune 50mg Tablet contains Dolutegravir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.
 
In some cases, Dalimune 50mg Tablet may cause side effects such as nausea, vomiting, headache, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to the doctor if the side effects persist or worsen.

Pregnancy testing should be performed in adolescents and adults of reproductive potential prior to starting Dolutegravir to rule out the use of Dolutegravir during the first trimester of pregnancy. Advise adolescents and adults with reproductive potential to take effective contraception on a regular basis. Avoid breastfeeding whilst on treatment with Dalimune 50mg Tablet. Dalimune 50mg Tablet may cause dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medications to prevent side effects/interactions.

Uses of Dalimune 50mg Tablet

HIV infection

Medicinal Benefits Mweb

Medicinal Benefits

Dalimune 50mg Tablet contains Dolutegravir, which belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Dalimune 50mg Tablet reduces the viral load in the body and keeps it at a low level. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

Directions for Use

Take Dalimune 50mg Tablet with or without food. Swallow it as a whole with water; do not chew or crush it.

Side Effects of Dalimune 50mg Tablet

  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea
  • Abdominal pain or discomfort
  • Dizziness
  • Fatigue
  • Flatulence (wind)

Drug Warnings

Do not take Dalimune 50mg Tablet if you are allergic to any of its components or if you are taking fampridine (used in multiple sclerosis) or dofetilide (used to treat heart conditions). Inform your doctor if you notice joint pain, bone problems, and stiffness or symptoms of infection/inflammation, such as fever, headache, stomach ache, and difficulty breathing. Let the doctor know if you are taking prescription/non-prescription medicines, including herbal products or supplements.

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
DolutegravirEtravirine
Severe

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with dofetilide may possibly reduce the blood levels and effects of Dalimune 50mg Tablet. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Dalimune 50mg Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
DolutegravirEtravirine
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with etravirine can reduce the blood levels and effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Etravirine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium lactate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with magnesium lactate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Magnesium lactate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Magnesium lactate. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Dalimune 50mg Tablet:
Zinc gluconate reduces the absorption of Dalimune 50mg Tablet, resulting in reduced efficacy of Dalimune 50mg Tablet in treating HIV.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Zinc gluconate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Zinc gluconate. If your condition worsens or develops new infections while taking these medications, it is important to contact a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DolutegravirFosphenytoin
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with fosphenytoin can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Fosphenytoin together can result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with rifampicin can decrease the blood levels of Dalimune 50mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dalimune 50mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dalimune 50mg Tablet:
Coadministration of Dalimune 50mg Tablet with zinc sulfate can reduce the efficacy of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Zinc sulfate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Zinc sulfate. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium gluconate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with magnesium aspartate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Magnesium gluconate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Magnesium gluconate. Do not discontinue using any medications without consulting a doctor.
DolutegravirDidanosine
Severe
How does the drug interact with Dalimune 50mg Tablet:
Co-administration of Dalimune 50mg Tablet with Didanosine can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Didanosine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Dalimune 50mg Tablet at least two hours before or six hours after the didanosine dose. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium chloride
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with magnesium chloride can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Magnesium chloride together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Magnesium chloride. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METFORMIN
  • RIFAMPICIN
  • PHENYTOIN
  • PHENOBARBITAL
  • OXCARBAZEPINE
  • CARBAMAZEPINE
  • St John's wort

Habit Forming

No

Special Advise

  • During HIV therapy, there may be weight gain, and increase in blood lipids and blood glucose levels. Regular monitoring is advised.
  • Discuss with your doctor about effective birth control methods that you can use during your treatment. 

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food, vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods. Avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

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