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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

DASATINIB-50MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7Th To 12Th Floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103.
Other Info - DAS0087

FAQs

Dasamyl 50 mg Tablet contains Dasatinib, which works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells.

Dasamyl 50 mg Tablet is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least six months after completion of the treatment.

Take antacids such as aluminium hydroxide/magnesium hydroxide, calcium carbonate, calcium carbonate, and magnesium 2 hours before or after taking Dasamyl 50 mg Tablet as antacids may alter the absorption of this medicine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Dasamyl 50 mg Tablet to prevent serious adverse effects.

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Pregnancy

Unsafe

When given to a pregnant woman, Dasamyl 50 mg Tablet may cause fetal harm. There have been no sufficient and well-controlled investigations of Dasamyl 50 mg Tablet in pregnant women. Women of reproductive potential should avoid becoming pregnant while undergoing treatment with this medicine.

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Breast Feeding

Unsafe

It is not known if Dasamyl 50 mg Tablet passes into your breast milk. Inform your doctor if you are breastfeeding. You should not breastfeed while taking this medicine and for 2 weeks of the treatment with Dasamyl 50 mg Tablet . Your doctor may prescribe an alternative based on the symptoms and health condition.

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Driving

Unsafe

Dasamyl 50 mg Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Dasamyl 50 mg Tablet or until you become alert.

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Liver

Caution

Use Dasamyl 50 mg Tablet with caution if you have liver disease. Your doctor may monitor your liver function while taking this medicine. No dose adjustments are necessary in patients with liver impairment.

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Kidney

Caution

There are presently no clinical investigations with Dasamyl 50 mg Tablet in patients with compromised renal function. If you have kidney problems, inform your doctor before taking this medicine.

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Children

Consult your doctor

Dasamyl 50 mg Tablet is safe for use in children above one year of age if prescribed by the doctor.

About Dasamyl 50 mg Tablet

Dasamyl 50 mg Tablet is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Dasamyl 50 mg Tablet is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Dasamyl 50 mg Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Dasamyl 50 mg Tablet may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dasamyl 50 mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Dasamyl 50 mg Tablet based on the severity of your condition.

Dasamyl 50 mg Tablet should be avoided if you are allergic to it or any other components present in it. Before taking Dasamyl 50 mg Tablet , caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Dasamyl 50 mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Dasamyl 50 mg Tablet

Philadelphia chromosome-positive chronic myeloid leukemia, Philadelphia chromosome-positive acute lymphoblastic leukemia.

Medicinal Benefits Mweb

Medicinal Benefits

Dasamyl 50 mg Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Dasamyl 50 mg Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.

Directions for Use

Take Dasamyl 50 mg Tablet as advised by your doctor. Do not take more than the prescribed dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Side Effects of Dasamyl 50 mg Tablet

  • Nausea
  • Diarrhoea
  • Decreased platelet count
  • Fatigue
  • Edema
  • Vomiting
  • Diarrhea
  • Headache
  • Back pain
  • Dizziness
  • Skin rash
  • Difficulty breathing
  • GI bleeding
  • Myalgia

Drug Warnings

Dasamyl 50 mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Dasamyl 50 mg Tablet in these patients may cause serious side effects. Dasamyl 50 mg Tablet may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Dasamyl 50 mg Tablet is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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DasatinibPimozide
Critical
DasatinibMesoridazine
Critical

Drug-Drug Interactions

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DasatinibPimozide
Critical
How does the drug interact with Dasamyl 50 mg Tablet:
Using Pimozide together with Dasamyl 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibMesoridazine
Critical
How does the drug interact with Dasamyl 50 mg Tablet:
Using Mesoridazine together with Dasamyl 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Dasamyl 50 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibDronedarone
Critical
How does the drug interact with Dasamyl 50 mg Tablet:
Using dronedarone together with Dasamyl 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibHalofantrine
Critical
How does the drug interact with Dasamyl 50 mg Tablet:
Using Halofantrine together with Dasamyl 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibPhenobarbital
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Taking Dasamyl 50 mg Tablet with Phenobarbital may significantly reduce the blood levels of Dasamyl 50 mg Tablet.

How to manage the interaction:
Taking Phenobarbital with Dasamyl 50 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
DasatinibStreptokinase
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Coadministration of Dasamyl 50 mg Tablet with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Streptokinase with Dasamyl 50 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience bruising, dizziness; red or black, tarry stools; severe headache; and weakness. Do not discontinue any medications without consulting a doctor.
DasatinibAmiodarone
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Co-administration of Dasamyl 50 mg Tablet with Amiodarone may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Dasamyl 50 mg Tablet with Amiodarone may cause an interaction, it is safe if a doctor has prescribed it. If you develop dizziness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
DasatinibDipyridamole
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Coadministration of Dasamyl 50 mg Tablet with Dipyridamole can increase the risk of bleeding tendencies.

How to manage the interaction:
Co-administration of Dasamyl 50 mg Tablet with Dipyridamole can result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like bruising, feeling dizzy or lightheaded, having dark stools, headaches, weakness, - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DasatinibNaproxen
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Using Dasamyl 50 mg Tablet with Naproxen may increase the risk or severity of bleeding problems.

How to manage the interaction:
Taking Dasamyl 50 mg Tablet with Naproxen together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DasatinibDalteparin
Severe
How does the drug interact with Dasamyl 50 mg Tablet:
Coadministration of Dasamyl 50 mg Tablet with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin and Dasamyl 50 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - bruising, dizziness, severe headache, or weakness - make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DASATINIB-50MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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DASATINIB-50MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Dasamyl 50 mg Tablet. Avoid consumption of Grapefruit juice with Dasamyl 50 mg Tablet. However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PANTOPRAZOLE
  • KETOCONAZOLE
  • ESOMEPRAZOLE
  • RITONAVIR
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • PHENYTOIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • ALUMINIUM HYDROXIDE

Habit Forming

No

Special Advise

  • A blood test, such as LFT and RFT, should be performed to check for liver/kidney function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).
  • An ECG and ECHO should be done in patients taking Dasamyl 50 mg Tablet to check for any signs of cardiac problems.

Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Dasamyl 50 mg Tablet Substitute

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