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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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in last 90 days

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANALGESICS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - DEB0030

Author Details

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FAQs

Debrilyse Plus Tablet contains Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside prevents swelling and inflammation by neutralizing the chemicals that cause cell damage. Diclofenac blocks the release of chemical substances that cause pain and inflammation.

Debrilyse Plus Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is tenderness and swelling in the joints.

Avoid exceeding the dose and duration advised by the doctor. Debrilyse Plus Tablet should not be taken for longer durations unless prescribed by your doctor.

If you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Debrilyse Plus Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Debrilyse Plus Tablet may cause blurred vision and dizziness. So, do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Debrilyse Plus Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Debrilyse Plus Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Debrilyse Plus Tablet is not recommended for children below 12 years of age.

About Debrilyse Plus Tablet

Debrilyse Plus Tablet is used to treat pain and inflammation associated with osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back) and rheumatoid arthritis (joint pain, especially in the hands and feet). It may also provide relief from toothache, ear pain, throat pain, muscle ache, and backache.

Debrilyse Plus Tablet contains Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside prevents swelling and inflammation by neutralizing the chemicals that cause cell damage. Diclofenac blocks the release of chemical substances that cause pain and inflammation.

Take Debrilyse Plus Tablet exactly as prescribed by your doctor. Debrilyse Plus Tablet may cause side-effects such as nausea, vomiting, stomach pain, indigestion, heartburn, stomach upset, diarrhoea, and headache. These side-effects are usually mild and temporary. However, if any of these side-effects persist or worsen, consult a doctor immediately.

Consult your doctor if you are pregnant or breastfeeding. Debrilyse Plus Tablet is not recommended for children below 12 years of age. Debrilyse Plus Tablet may cause dizziness, so do not drive or operate heavy machinery unless you are alert. Keep your doctor informed about your health conditions and medications to rule out any interactions/side effects.

Uses of Debrilyse Plus Tablet

Pain relief

Medicinal Benefits Mweb

Medicinal Benefits

Debrilyse Plus Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain are enzymes with antiseptic and anti-inflammatory properties. They reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralizing the chemicals (free radicals) that cause cell damage. Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) that prevents the production of chemical substances (prostaglandins) that cause pain and inflammation.

Directions for Use

Take Debrilyse Plus Tablet with food to avoid stomach upset. Swallow Debrilyse Plus Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Debrilyse Plus Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Indigestion
  • Heartburn
  • Stomach upset
  • Diarrhoea
  • Headache

Drug Warnings

Do not take Debrilyse Plus Tablet if you are allergic to any of its contents. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, blood clotting disorder, a habit of smoking, or liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Debrilyse Plus Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacMethotrexate
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of Debrilyse Plus Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Debrilyse Plus Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacMethotrexate
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of methotrexate with Debrilyse Plus Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Debrilyse Plus Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacTacrolimus
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of Debrilyse Plus Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacBromfenac
Severe
How does the drug interact with Debrilyse Plus Tablet:
Taking Debrilyse Plus Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Debrilyse Plus Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacSirolimus
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of Debrilyse Plus Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacRivaroxaban
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of Rivaroxaban together with Debrilyse Plus Tablet may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacOxaprozin
Severe
How does the drug interact with Debrilyse Plus Tablet:
Taking Debrilyse Plus Tablet and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacFurosemide
Severe
How does the drug interact with Debrilyse Plus Tablet:
Concomitant administration of Debrilyse Plus Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Debrilyse Plus Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co administration of Debrilyse Plus Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacMipomersen
Severe
How does the drug interact with Debrilyse Plus Tablet:
Co-administration of Debrilyse Plus Tablet with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Debrilyse Plus Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • WARFARIN
  • DULOXETINE
  • LITHIUM
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • Try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Debrilyse Plus Tablet Substitute

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