apollo
0
Write a Review
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

DACARBAZINE-500MG

Manufacturer/Marketer :

Adonis Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - DEC0093

FAQs

DECARB 500MG INJECTION contains Dacarbazine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

DECARB 500MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Unsafe

Avoid alcohol consumption while on treatment with DECARB 500MG INJECTION to prevent serious side effects.

bannner image

Pregnancy

Unsafe

DECARB 500MG INJECTION is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving DECARB 500MG INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving DECARB 500MG INJECTION. Your doctor may suggest you stop feeding while on treatment with this medicine.

bannner image

Driving

Caution

DECARB 500MG INJECTION will be administered in the hospital setting. Hence, driving is not recommended.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving DECARB 500MG INJECTION. It may cause hepatic necrosis when administered with other antineoplastics. Hence, DECARB 500MG INJECTION should be used with caution in patients with liver problems. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving DECARB 500MG INJECTION. It should be used with caution in patients with renal impairment. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

bannner image

Children

Consult your doctor

Limited information is available for the use of DECARB 500MG INJECTION in children. It will be administered to the children only if clearly needed. If administered, careful monitoring of the child is needed.

icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

About DECARB 500MG INJECTION

DECARB 500MG INJECTION is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. DECARB 500MG INJECTION is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. DECARB 500MG INJECTION is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs.

DECARB 500MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

DECARB 500MG INJECTION may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. DECARB 500MG INJECTION is a parenteral preparation. A trained healthcare professional will administer it. 

DECARB 500MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including medications you take, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or heart problems. DECARB 500MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring of blood and liver functioning should be done during the entire treatment. This medicine is known to cause fetal harm if used in pregnancy. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding before taking DECARB 500MG INJECTION.

Uses of DECARB 500MG INJECTION

Metastatic Malignant Melanoma, Hodgkin’s Disease.

Medicinal Benefits Mweb

Medicinal Benefits

DECARB 500MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Directions for Use

DECARB 500MG INJECTION will be administered by a trained healthcare professional. Hence, do not self-administer. 

Side Effects of DECARB 500MG INJECTION

  • Nausea
  • Dizziness
  • Fever
  • Chills
  • Sore throat
  • Headache
  • Vomiting
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

Drug Warnings

DECARB 500MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or cardiac disorders. DECARB 500MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women and breastfeeding mothers. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. It is unknown whether DECARB 500MG INJECTION can be administered to children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

verifiedApollotooltip
DacarbazineBaricitinib
Severe
DacarbazineEtanercept
Severe

Drug-Drug Interactions

Login/Sign Up

DacarbazineBaricitinib
Severe
How does the drug interact with Decarb 500mg Injection:
Coadministration of Decarb 500mg Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Baricitinib and Decarb 500mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DacarbazineEtanercept
Severe
How does the drug interact with Decarb 500mg Injection:
When Etanercept is used with Decarb 500mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Decarb 500mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DacarbazineCladribine
Severe
How does the drug interact with Decarb 500mg Injection:
The combined use of cladribine with Decarb 500mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Decarb 500mg Injection and Cladribine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DacarbazineClozapine
Severe
How does the drug interact with Decarb 500mg Injection:
Combining Decarb 500mg Injection with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
Although taking Decarb 500mg Injection and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
DacarbazineInfliximab
Severe
How does the drug interact with Decarb 500mg Injection:
When Decarb 500mg Injection is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Decarb 500mg Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DacarbazineThalidomide
Severe
How does the drug interact with Decarb 500mg Injection:
Taking thalidomide together with Decarb 500mg Injection may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Decarb 500mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DacarbazineKetoconazole
Severe
How does the drug interact with Decarb 500mg Injection:
When Decarb 500mg Injection is taken with Ketoconazole, it can increase the risk of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Decarb 500mg Injection and Ketoconazole, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
DacarbazineTofacitinib
Severe
How does the drug interact with Decarb 500mg Injection:
Taking Decarb 500mg Injection with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
There may be a possibility of interaction between Decarb 500mg Injection and Tofacitinib, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • ABACAVIR
  • ZIDOVUDINE
  • ADEFOVIR
  • WARFARIN
  • ACENOCOUMAROL
  • PHENYTOIN
  • ABATACEPT

Habit Forming

No

Special Advise

  • DECARB 500MG INJECTION should be administered only by a trained and experienced oncologist.
  • A blood test should be performed, such as LFT and RFT, to check for liver/ and kidney function.
  • Weekly blood tests should be done for after the dose is administered to check for CBC (Complete blood count).

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid going out in the hot sun, as it can harm your skin.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.

DECARB 500MG INJECTION Substitute

Substitutes safety advice
  • Celdaz 500 Injection 1's

    by Others

    522.50per tablet
  • DABAZ 500MG INJECTION

    by Others

    552.00per tablet
  • DACAREX 500MG INJECTION

    by Others

    994.86per tablet
  • Dacmed 500 Injection 1's

    by Others

    906.39per tablet
  • Dacarb 500 mg Injection 1's

    by Others

    519.30per tablet
winter care Floating Button
winter care Floating Button