Despram Plus 5mg Tablet

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Despram Plus 5mg Tablet 10's

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Written By Veda Maddala , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

CLONAZEPAM-0.5MG+ESCITALOPRAM OXALATE-10MG

Manufacturer/Marketer :

Legrand Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANXIOLYTICS]

Country of origin

INDIA

Manufacturer/Marketer address

D-No : 20 - 130 - 2, Kothagraharam ,Changala Rao Peta ,Visakhapatnam 530001, Andhra Pradesh

Other Info - DES0117

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

We provide you with authentic, trustworthy and relevant information

FAQs

How does Despram Plus 5mg Tablet work?

Despram Plus 5mg Tablet works by decreasing the activity in the brain and producing a calming effect. It improves mood, behaviour and cognition in patients with anxiety.

Can Despram Plus 5mg Tablet be used for long-term?

Long-term use of Despram Plus 5mg Tablet may cause suicidal thoughts in some cases. So, use the Despram Plus 5mg Tablet for the duration only as prescribed by your doctor. Consult your doctor immediately if you notice any behavioural changes during the use of Despram Plus 5mg Tablet .

How can I know if I have anxiety?

Anxiety is a feeling of fear, worry, or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling, and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.

Can Despram Plus 5mg Tablet cause erectile dysfunction?

Despram Plus 5mg Tablet may cause a decrease in sexual desire (libido) in men and women. Men can also experience erectile dysfunction. Consult your doctor if you experience any change in sexual desire after taking Despram Plus 5mg Tablet .

Does using Despram Plus 5mg Tablet cause hair loss?

Despram Plus 5mg Tablet may cause hair loss in rare cases. If you experience excessive hair loss, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Alcohol

Safe if prescribed

Do not consume alcohol while on treatment with Despram Plus 5mg Tablet as it can increase the risk of side effects such as dizziness and drowsiness.

Pregnancy

Consult your doctor

Despram Plus 5mg Tablet may show toxic effects on the fetus. So, it is not recommended for use in women who are pregnant or planning pregnancy. Consult your doctor for further advice.

Breast Feeding

Consult your doctor

Despram Plus 5mg Tablet should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

Driving

Safe if prescribed

Do not drive vehicles or operate heavy machinery as Despram Plus 5mg Tablet may cause drowsiness.

Liver

Consult your doctor

Despram Plus 5mg Tablet should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

Kidney

Consult your doctor

Despram Plus 5mg Tablet should be used with caution in patients with kidney failure. Please consult your doctor if you have kidney problems.

Children

Safe if prescribed

Despram Plus 5mg Tablet is not recommended for children as safety and effectiveness have not been established.

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Reference

About Despram Plus 5mg Tablet

Despram Plus 5mg Tablet belongs to a group of medications called ‘antianxiety medications' used in the treatment of anxiety disorders. Anxiety is a mental health disorder characterized by feelings of intense, excessive and persistent worry or fear that are strong enough to interfere with one’s daily activities. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Despram Plus 5mg Tablet is a combination of two drugs: clonazepam and escitalopram oxalate. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Take Despram Plus 5mg Tablet as prescribed by the doctor. Sometimes, Despram Plus 5mg Tablet may cause common side effects such as nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Consult your doctor if any of these side effects persist or worsen.

Do not take Despram Plus 5mg Tablet if you are allergic to any of its components. Inform your doctor if you have seizures, liver problems, sleep disorders, lung problems, and alcohol or drug abuse. Do not consume alcohol as it can increase the risk of side effects. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. Despram Plus 5mg Tablet may cause dizziness and drowsiness, so avoid driving vehicles or operating machinery unless you are alert.

Uses of Despram Plus 5mg Tablet

Anxiety disorder

Medicinal Benefits Mweb

Key Benefits

Despram Plus 5mg Tablet is a combination of two medicines: clonazepam and escitalopram oxalate. It is used to treat anxiety disorders. Clonazepam increases the effect of gamma-aminobutyric acid (GABA) and produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate is a selective serotonin reuptake inhibitor (SSRI); it increases the serotonin levels in the brain, thereby improving mood and behaviour.

Directions for Use

Take Despram Plus 5mg Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Side Effects of Despram Plus 5mg Tablet

Nausea
Vomiting
Diarrhoea
Dizziness
Confusion
Uncoordinated body movements
Drowsiness
Fatigue
Delayed ejaculation
Decreased libido (low sexual desire)
Memory problems

Drug Warnings

Do not take Despram Plus 5mg Tablet if you are allergic to any of the ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or antibiotics. Talk to your doctor if you have a history of seizures, bipolar disorder, or schizophrenia. Patients with liver diseases, diabetes, heart disease, and bleeding disorders should use Despram Plus 5mg Tablet with caution. Please do not stop taking Despram Plus 5mg Tablet abruptly as it can cause withdrawal symptoms. Despram Plus 5mg Tablet may cause suicidal thoughts and worsen anxiety.

Drug-Drug Interactions Checker List

SELEGILINE
MOCLOBEMIDE
CIMETIDINE
LINEZOLID
RIFAMPICIN

Habit Forming

Yes

Special Advise

Your doctor may advise regular eye checkups as using Despram Plus 5mg Tablet may worsen the symptoms in patients with open-angle glaucoma.
Consult your doctor immediately if there is any change in behaviour or if you have any suicidal thoughts.

Diet & Lifestyle Advise

Attend therapy sessions regularly.
Eat a healthy diet.
Try to stay active and exercise regularly.
Take ample rest. Get enough sleep.
Meditate regularly as it helps in easing anxiety.
Avoid smoking, caffeine, and alcohol consumption.
Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

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