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Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

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Whats That

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Composition :

ONDANSETRON-8MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIEMETICS

Country of origin

India
Other Info - DE51745

FAQs

Destirone 8mg Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.

Tell your doctor if you are facing severe constipation as after checking your condition, the doctor will decide that you can take this medicine or not.

Destirone 8mg Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Destirone 8mg Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Destirone 8mg Tablet daily. Taking Destirone 8mg Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Disclaimer

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Alcohol

Unsafe

One should avoid consuming alcohol while taking Destirone 8mg Tablet as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

Destirone 8mg Tablet could be used during pregnancy after consulting a doctor.

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Breast Feeding

Safe if prescribed

Destirone 8mg Tablet could be used during breastfeeding after consulting a doctor.

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Driving

Caution

Destirone 8mg Tablet may cause lightheadedness in the body, so a person taking Destirone 8mg Tablet should avoid driving or operating any heavy machinery or tasks that require mental alertness.

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Liver

Safe if prescribed

In persons dealing with liver problems, the use of Destirone 8mg Tablet is allowed if prescribed by the doctor. However, in patients with severe liver problems should take a low dose of Destirone 8mg Tablet as much as possible. Do not take more than 8 mg of Destirone 8mg Tablet per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Destirone 8mg Tablet is safe in patients dealing with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Destirone 8mg Tablet should not be given to the children below 4 years of age. The use of Destirone 8mg Tablet is safe in children above 4 years of age if prescribed by the doctor.

About Destirone 8mg Tablet

Destirone 8mg Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Destirone 8mg Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Destirone 8mg Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Destirone 8mg Tablet as prescribed. Your doctor will advise you on how often you take Destirone 8mg Tablet based on your medical condition. A person taking Destirone 8mg Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Destirone 8mg Tablet, and even some of the unpleasant effects of Destirone 8mg Tablet do not require medical attention.

The use of Destirone 8mg Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Destirone 8mg Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Destirone 8mg Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Destirone 8mg Tablet

Nausea, Vomiting

Medicinal Benefits Mweb

Medicinal Benefits

Destirone 8mg Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Destirone 8mg Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.Syrup/Suspension: Shake the bottle well before use and take it as prescribed by your doctor with a measuring cup or spoon.

Side Effects of Destirone 8mg Tablet

  • Sensations of flushing
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Destirone 8mg Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Destirone 8mg Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Destirone 8mg Tablet daily. Destirone 8mg Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Destirone 8mg Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronOsimertinib
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Destirone 8mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronOsimertinib
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Destirone 8mg Tablet along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronRibociclib
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with ribociclib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Destirone 8mg Tablet along with ribociclib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronFentanyl
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking fentanyl with Destirone 8mg Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking fentanyl with Destirone 8mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
OndansetronBedaquiline
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with bedaquiline increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Destirone 8mg Tablet along with bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronToremifene
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with toremifene increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Destirone 8mg Tablet along with toremifene can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronVilazodone
Severe
How does the drug interact with Destirone 8mg Tablet:
When Vilazodone is taken with Destirone 8mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Destirone 8mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
OndansetronPentazocine
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Pentazocine with Destirone 8mg Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Taking Destirone 8mg Tablet with Pentazocine together can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
OndansetronEscitalopram
Severe
How does the drug interact with Destirone 8mg Tablet:
Taking Destirone 8mg Tablet with escitalopram may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Destirone 8mg Tablet along with escitalopram can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
OndansetronBupropion
Severe
How does the drug interact with Destirone 8mg Tablet:
When bupropion, is combined with Destirone 8mg Tablet it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Destirone 8mg Tablet along with bupropion can lead to interaction, it can be taken if recommended by a doctor. If you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • TRAMADOL
  • IBUPROFEN
  • PREGABALIN
  • LORAZEPAM

Habit Forming

No

Special Advise

  • Do not use Destirone 8mg Tablet with Apomorphine as it can cause a sudden fall of blood pressure leading to death or coma.
  • Destirone 8mg Tablet contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake. 

Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 
  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Destirone 8mg Tablet Substitute

Substitutes safety advice
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