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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Omenta Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANALGESICS

Country of origin

INDIA

Manufacturer/Marketer address

Omenta Pharma Private Limited 7,Shopping Centre,1st Floor, Karampura New Delhi- 110015 India
Other Info - DIC0144

Author Details

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FAQs

Diclozyme-P Tablet contains Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase is a protein enzyme that helps break down and dissolves the abnormal proteins at the inflammation site, thereby reducing pain.

Diclozyme-P Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Diarrhoea might be a side-effect of Diclozyme-P Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Diclozyme-P Tablet should not be taken for longer durations unless prescribed by the doctor. If Diclozyme-P Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

Avoid taking Diclozyme-P Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Diclozyme-P Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Diclozyme-P Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Diclozyme-P Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Diclozyme-P Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Diclozyme-P Tablet should not be given to children less than 10 years of age, as the safety and effectiveness have not been established.

About Diclozyme-P Tablet

Diclozyme-P Tablet belongs to the class of combination medication called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints which causes pain and joint stiffness.

Diclozyme-P Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent thereby decreasing swelling at the painful site. 
 
You are advised to take Diclozyme-P Tablet for as long as your doctor has prescribed it for you. In some cases, Diclozyme-P Tablet may cause certain common side-effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Diclozyme-P Tablet may cause drowsiness and dizziness, so drive with caution. Diclozyme-P Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Diclozyme-P Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Diclozyme-P Tablet

Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Medicinal Benefits Mweb

Medicinal Benefits

Diclozyme-P Tablet is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Diclozyme-P Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Diclozyme-P Tablet increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reduces inflammation. 

Directions for Use

Take Diclozyme-P Tablet with food. Swallow Diclozyme-P Tablet as a whole with a glass of water; do not chew or break it.

Side Effects of Diclozyme-P Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

Drug Warnings

Do not take Diclozyme-P Tablet if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Diclozyme-P Tablet may cause drowsiness and dizziness, so drive only if you are alert. Diclozyme-P Tablet is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Diclozyme-P Tablet as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Diclozyme-P Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Diclozyme-P Tablet unless prescribed.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacDabigatran etexilate
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Diclozyme-P Tablet:
Co-administration of Diclozyme-P Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Diclozyme-P Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacDabigatran etexilate
Severe
How does the drug interact with Diclozyme-P Tablet:
Concomitant use of Diclozyme-P Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Diclozyme-P Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacPonatinib
Severe
How does the drug interact with Diclozyme-P Tablet:
Taking Diclozyme-P Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Diclozyme-P Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacNaproxen
Severe
How does the drug interact with Diclozyme-P Tablet:
Coadministration of Diclozyme-P Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diclozyme-P Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacSulindac
Severe
How does the drug interact with Diclozyme-P Tablet:
Co-administration of Diclozyme-P Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Diclozyme-P Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Diclozyme-P Tablet:
Taking Diclozyme-P Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Diclozyme-P Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacFondaparinux
Severe
How does the drug interact with Diclozyme-P Tablet:
Coadministration of Diclozyme-P Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Diclozyme-P Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacPiroxicam
Severe
How does the drug interact with Diclozyme-P Tablet:
Taking Diclozyme-P Tablet and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Diclozyme-P Tablet and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacBromfenac
Severe
How does the drug interact with Diclozyme-P Tablet:
Taking Diclozyme-P Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Diclozyme-P Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacHuman immunoglobulin
Severe
How does the drug interact with Diclozyme-P Tablet:
Taking Diclozyme-P Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Diclozyme-P Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CYCLOSPORINE
  • TACROLIMUS
  • LITHIUM
  • DIGOXIN
  • WARFARIN
  • METHOTREXATE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • MICONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • AMIDODARONE
  • SULFINPYRAZONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • CHLORAMPHENICOL
  • MIFEPRESTONE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Diclozyme-P Tablet Substitute

Substitutes safety advice
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