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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIARRHYTHMICS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - DIGI278

Author Details

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FAQs

It may take several weeks for Digitran 0.25mg Tablet to show its effect. You are recommended to continue taking Digitran 0.25mg Tablet for as long as your doctor prescribes it and do not stop taking Digitran 0.25mg Tablet suddenly as it may worsen your heart problems. However, if you experience any difficulty while taking Digitran 0.25mg Tablet, please consult your doctor.

Yes, Digitran 0.25mg Tablet may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Digitran 0.25mg Tablet to experience this side effect. You are recommended to drink plenty of fluids to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsen, please consult your doctor.

Yes, Digitran 0.25mg Tablet may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.

No, you can eat normally. However, a balanced and healthy diet are advised for effective results.

You are not recommended to take more than the prescribed dose of Digitran 0.25mg Tablet as it may cause Digitran 0.25mg Tablet toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances (more than usual yellow-green). However, if you experience any of these symptoms while taking Digitran 0.25mg Tablet, please consult a doctor immediately.

No, you are not recommended to take amiodarone with Digitran 0.25mg Tablet as co-administration of these two medicines may increase the levels of Digitran 0.25mg Tablet in the blood resulting in Digitran 0.25mg Tablet toxicity. However, please consult a doctor before taking other medicines with Digitran 0.25mg Tablet so that the dose may be adjusted appropriately.

You are recommended to avoid taking Digitran 0.25mg Tablet if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Digitran 0.25mg Tablet as it may increase drowsiness and reduce the amount of Digitran 0.25mg Tablet in blood leading to abnormal heart function.

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Pregnancy

Caution

Tablet: It is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Tablet: It is safe for breastfeeding mothers if prescribed by a doctor.

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Driving

Caution

Digitran 0.25mg Tablet may cause dizziness, yellow or blurred vision in some people. So, make sure you are not affected before driving or operating machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Digitran 0.25mg Tablet in patients with Liver problems, please consult a doctor.

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Kidney

Caution

Take Digitran 0.25mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Paediatric solution is to be used in children in doses as prescribed by a child specialist.

About Digitran 0.25mg Tablet

Digitran 0.25mg Tablet belongs to a group of medicines called cardiac glycosides used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Digitran 0.25mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduces the rate of heart contractions. Digitran 0.25mg Tablet works on the heart muscle directly and increases the force with which heart muscle contracts with each heartbeat. Thereby, it makes heart efficient in pumping blood around the body and slows down the rate at which heartbeats.

Take Digitran 0.25mg Tablet as prescribed. Your doctor will recommend you how often you take Digitran 0.25mg Tablet based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Digitran 0.25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Digitran 0.25mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Digitran 0.25mg Tablet to monitor the amount of Digitran 0.25mg Tablet in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused due to vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Digitran 0.25mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digitran 0.25mg Tablet has a very narrow therapeutic index. It means small differences in dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors like regular electrocardiogram (ECG). So, try not to self-medicate and suggest Digitran 0.25mg Tablet to others.

Uses of Digitran 0.25mg Tablet

Irregular heartbeats, Prevention of heart failure

Medicinal Benefits Mweb

Medicinal Benefits

Digitran 0.25mg Tablet is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Digitran 0.25mg Tablet increases the force with which heart muscle contracts with each heartbeat and makes heart efficient in pumping blood around the body. Thus, slows down the rate at which heartbeats and makes heart rate normal. Digitran 0.25mg Tablet improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

Directions for Use

Tablet: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Paediatric solution: Shake the bottle well before use. Check the label for directions and give it with or without food in doses as prescribed by a doctor with the help of a dosing syringe.

Side Effects of Digitran 0.25mg Tablet

  • Feeling confused
  • Dizziness
  • Nausea or vomiting
  • Loss of appetite
  • Diarrhoea
  • Changes in your vision (including blurred vision and not able to look at bright light)

Drug Warnings

If you are known to be allergic to Digitran 0.25mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid intake of alcohol with Digitran 0.25mg Tablet as it may increase the risk of drowsiness. Digitran 0.25mg Tablet may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Digitran 0.25mg Tablet to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Digitran 0.25mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digitran 0.25mg Tablet has a narrow therapeutic index which makes its use limited and requires close monitoring as small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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DigoxinBretylium tosilate
Severe

Drug-Drug Interactions

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DigoxinBretylium tosilate
Severe
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet and Bretylium tosilate may increase the effect of Digitran 0.25mg Tablet.

How to manage the interaction:
Although taking Bretylium tosilate and Digitran 0.25mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling sick, throwing up, having seizures, feeling tired, or noticing your heart beating too fast or too slow, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet and Lapatinib may increase the blood levels and effects of Digitran 0.25mg Tablet.

How to manage the interaction:
If you are supposed to take Digitran 0.25mg Tablet and Lapatinib together, a doctor may adjust the dose or monitor more frequently to safely use both medications. If you experience diarrhea, nausea, loss of appetite, vomiting, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, contact a doctor as these may be signs and symptoms of excessive Digitran 0.25mg Tablet levels. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Calcium carbonate and Digitran 0.25mg Tablet may increase the calcium levels may increase the effects of Digitran 0.25mg Tablet

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Digitran 0.25mg Tablet if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet and Famotidine may increase the level or effect of Digitran 0.25mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Digitran 0.25mg Tablet and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet with Telaprevir may increase the blood levels and effects of Digitran 0.25mg Tablet.

How to manage the interaction:
Although taking Telaprevir and Digitran 0.25mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Digitran 0.25mg Tablet levels. Do not stop using any medications without a doctor's advice.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet and Glycopyrronium bromide may increase the serum concentration of Digitran 0.25mg Tablet and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Digitran 0.25mg Tablet and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Sucralfate together with Digitran 0.25mg Tablet may decrease the effects of Digitran 0.25mg Tablet.

How to manage the interaction:
If you are supposed to take Digitran 0.25mg Tablet and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Digitran 0.25mg Tablet and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Fingolimod with Digitran 0.25mg Tablet may increase the risk or severity of slowing down of the heart rate.

How to manage the interaction:
Although there is a possible interaction between Digitran 0.25mg Tablet and Fingolimod, you can take these medicines together if prescribed by a doctor. It's important to monitor your heart rate and talk to a doctor about any alternative medications that don't interact. If you experience any symptoms like chest pain, shortness of breath, or fainting, it's important to call your doctor right away. Do not discontinue any medications without consulting a doctor.
DigoxinDolasetron
Severe
How does the drug interact with Digitran 0.25mg Tablet:
Co-administration of Digitran 0.25mg Tablet with Dolasetron can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Digitran 0.25mg Tablet with Dolasetron can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these risk factors or if you experience symptoms like an irregular heartbeat, dizziness, fainting, or a fast or irregular heartbeat, it is important to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Digitran 0.25mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Digitran 0.25mg Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Digitran 0.25mg Tablet.

Drug-Diseases Interactions

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DIGOXIN-0.25MGOther conduction disorders
Severe
DIGOXIN-0.25MGAbnormalities of heart beat
Severe

Drug-Diseases Interactions

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DIGOXIN-0.25MGOther conduction disorders
Severe
How does the disease interact with Digitran 0.25mg Tablet:
In cases like the Wolff-Parkinson-White syndrome, Digitran 0.25mg Tablet may improve accessory route conduction.

How to manage the interaction:
Digitran 0.25mg Tablet should be used with caution in patients with Wolff-Parkinson-White syndrome (a heart condition that causes rapid heartbeat).
DIGOXIN-0.25MGAbnormalities of heart beat
Severe
How does the disease interact with Digitran 0.25mg Tablet:
Digitran 0.25mg Tablet prolongs the PR interval by slowing sinoatrial and AV conduction. Digitran 0.25mg Tablet therapy can cause severe sinus bradycardia or sinoatrial block in people with preexisting sinus node dysfunction, and it can cause progressive or full heart block in patients with incomplete AV block.

How to manage the interaction:
Digitran 0.25mg Tablet may be administered to patients with complete, stable AV block (an electrical signal that controls your heartbeat is partially or completely blocked) who have congestive heart failure, provided the block was not induced by cardiac glycosides.
DIGOXIN-0.25MGDisorders of mineral metabolism
Severe
How does the disease interact with Digitran 0.25mg Tablet:
Digitran 0.25mg Tablet and calcium have cumulative effects on inotropy. As a result, Digitran 0.25mg Tablet toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Digitran 0.25mg Tablet, and serum calcium levels should be monitored during therapy.
DIGOXIN-0.25MGDisorders of mineral metabolism
Severe
How does the disease interact with Digitran 0.25mg Tablet:
Digitran 0.25mg Tablet and calcium have cumulative effects on inotropy. As a result, Digitran 0.25mg Tablet toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Digitran 0.25mg Tablet, and serum calcium levels should be monitored during therapy.
DIGOXIN-0.25MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Digitran 0.25mg Tablet:
Digitran 0.25mg Tablet makes the myocardium more sensitive when potassium and/or magnesium are depleted. Despite Digitran 0.25mg Tablet serum drug concentrations, Digitran 0.25mg Tablet toxicity may happen in patients with hypokalemia or hypomagnesemia.

How to manage the interaction:
Digitran 0.25mg Tablet should be used with caution in patients with or who are at risk of developing potassium and/or magnesium deficiency, including patients on diuretic therapy; those with primary or secondary aldosteronism (may have low potassium levels), severe or prolonged diarrhoea or vomiting, malnutrition; and renal dialysis patients. Electrolyte imbalances may be corrected before starting the treatment.
DIGOXIN-0.25MGThyrotoxicosis [hyperthyroidism]
Moderate
How does the disease interact with Digitran 0.25mg Tablet:
Treatment of the underlying illness is the best way to control heart failure and/or atrial arrhythmias brought on by hypermetabolic or hyperdynamic conditions such hyperthyroidism, hypoxia, or arteriovenous shunt.

How to manage the interaction:
Digitran 0.25mg Tablet should be used with caution in patients with hyperthyroidism. Your doctor may adjust the dose secondary to changes in the thyroid condition.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • QUINIDINE
  • ATAZANAVIR
  • SAQUINAVIR
  • CLARITHROMYCIN
  • ITRACONAZOLE
  • ADENOSINE
  • DOLASETRON
  • ARBUTAMINE
  • CERITINIB
  • LAPATINIB
  • FINGOLIMOD
  • FLIBANSERIN
  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE

Habit Forming

No

Special Advise

  • Regular blood tests are advised while taking Digitran 0.25mg Tablet to monitor digoxin levels in the blood, potassium levels and kidney functioning.
  • Low salt diet and regular exercise are recommended along with Digitran 0.25mg Tablet for effective results.
  • Regular electrocardiogram (ECG) should be done to see the effect of Digitran 0.25mg Tablet on your heartbeat.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do the regular exercise as it helps to lower blood pressure and keeps blood vessels and heart in good condition.
  • Quit smoking as smoking increases blood pressure and heart rate.
  • Eat balanced and healthy diet which includes plenty of vegetables, fruits, low fat or fat free products.

Digitran 0.25mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

  • Lanoxin Tablet 10's

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    1.31per tablet
  • Dixin 0.25 mg Tablet 10's

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    1.28per tablet
  • Digoxin-0.25 Tablet 10's

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    1.17per tablet
  • Digon 0.25 mg Tablet 10's

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    1.26per tablet
  • Zigoxin 0.25 mg Tablet 10's

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    1.44per tablet

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