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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIDIABETICS
Other Info - DI45555

FAQs

Dioglip Plus 15mg/1mg Tablet is used to lower the blood sugar however if your sugar level gets reduced to a very low level and you start experiencing symptoms including hunger, sweating, dizziness, headache and feeling shaky. To treat such a condition, it is suggested to keep a fast-acting source of sugar in your bag that include hard candy, raisins and non-diet soda and consult your doctor immediately.

Controlling blood sugar in pregnancy becomes very important as it may cause complications in both mother and unborn child. However, the Dioglip Plus 15mg/1mg Tablet should be stopped before few days of the due date, your doctor may switch to other medication.

Dioglip Plus 15mg/1mg Tablet increases the chances of ovulation even if the woman is at her premenopause stage or not getting her regular periods, so it is advised to use an effective birth control method while taking Dioglip Plus 15mg/1mg Tablet.

Dioglip Plus 15mg/1mg Tablet should not be used in certain medical conditions that include diabetic ketoacidosis (dangerously high blood sugar levels), severe heart failure and active bladder cancer.

Colesevelam may reduce the absorption of Dioglip Plus 15mg/1mg Tablet, so it is advised to take Dioglip Plus 15mg/1mg Tablet at least 4 hours before taking colesevelam.

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

Hypoglycemia refers to low blood sugar levels and it is one of the side effects of Dioglip Plus 15mg/1mg Tablet. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact the doctor as it can be a condition of diabetes.

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you and consult your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Dioglip Plus 15mg/1mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Dioglip Plus 15mg/1mg Tablet is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

It is highly recommended to consult your doctor before taking Dioglip Plus 15mg/1mg Tablet.

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Driving

Caution

Dioglip Plus 15mg/1mg Tablet will not affect your ability to drive or use machines but take care if you experience abnormal vision.

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Liver

Caution

Dioglip Plus 15mg/1mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Dioglip Plus 15mg/1mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Dioglip Plus 15mg/1mg Tablet in children have not been established. Dioglip Plus 15mg/1mg Tablet is not recommended in children unless prescribed by a child specialist.

About Dioglip Plus 15mg/1mg Tablet

Dioglip Plus 15mg/1mg Tablet belongs to a group of medicines known as 'antidiabetics', used to treat type 2 (non-insulin-dependent) diabetes mellitus. In type 2 diabetes the body doesn't make enough insulin, or the insulin is not effectively used by the body. This is a type of diabetes that usually develops in adulthood. Insulin is a natural substance released by the body to break down the sugar of the body.

Dioglip Plus 15mg/1mg Tablet is a combination of two drugs namely 'Pioglitazone' and 'Glimepiride'. Pioglitazone belongs to the class of thiazolidinedione (TZD) also called 'glitazones' which helps control the level of sugar in your blood by helping your body to make better use of the insulin it produces. Glimepiride belongs to a class of medicines known as 'sulfonylureas', which works by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This drug also works best for individuals whose bodies naturally produce insulin. 

Take Dioglip Plus 15mg/1mg Tablet as suggested by the doctor. You are advised to take Dioglip Plus 15mg/1mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain) and pharyngitis. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these undesirable effects persistently.

Dioglip Plus 15mg/1mg Tablet should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to Dioglip Plus 15mg/1mg Tablet or any of the other ingredients of Dioglip Plus 15mg/1mg Tablet, have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeeding. Safety and efficacy of Dioglip Plus 15mg/1mg Tablet in children under 18 years have not been established, so it should not be given to them. Dioglip Plus 15mg/1mg Tablet is safe to taken by elderly persons whose age is 65 or over if prescribed by the doctor.

Uses of Dioglip Plus 15mg/1mg Tablet

Type 2 diabetes mellitus

Medicinal Benefits Mweb

Medicinal Benefits

Dioglip Plus 15mg/1mg Tablet is an antidiabetic drug used along with a proper diet and exercise to control high blood sugar (hyperglycemia) in patients with type 2 diabetes. Dioglip Plus 15mg/1mg Tablet works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar. Dioglip Plus 15mg/1mg Tablet may be used on its own in patients who are unable to take metformin and where treatment with diet and exercise has failed to control blood sugar. As Dioglip Plus 15mg/1mg Tablet helps to control the high blood sugar levels in the body, so it prevents the risk of blindness, nerve problems, kidney damage and other serious medical issues like a heart attack.

Directions for Use

Take Dioglip Plus 15mg/1mg Tablet as advised by the doctor. Swallow it as a whole with a full glass of water. Do not crush, break or chew it.

Side Effects of Dioglip Plus 15mg/1mg Tablet

  • Headache
  • Sinusitis
  • Myalgia (muscle pain)
  • Upper respiratory tract infection
  • Urinary tract infection
  • Diarrhea
  • Nausea
  • Pharyngitis (inflammation of pharynx located back of neck)

Drug Warnings

Dioglip Plus 15mg/1mg Tablet should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Dioglip Plus 15mg/1mg Tablet suddenly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy), and nerve damage (neuropathy). Dioglip Plus 15mg/1mg Tablet is used to lower the blood sugar however if your sugar level gets reduced to a very low level and you start experiencing symptoms including hunger, sweating, dizziness, headache and feeling shaky. To treat such a condition, it is suggested to keep a fast-acting source of sugar in your bag that includes hard candy, raisins, and non-diet soda. Fluid retention (edema) may occur and can lead to congestive heart failure so, combination use with insulin and use in heart failure may increase the risk in patients taking Dioglip Plus 15mg/1mg Tablet. You should not take Dioglip Plus 15mg/1mg Tablet if you have kidney disease, as measured by a blood test. Dioglip Plus 15mg/1mg Tablet, when used with or without insulin, tends to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking Dioglip Plus 15mg/1mg Tablet. Patients with bladder cancer and macular edema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Dioglip Plus 15mg/1mg Tablet.

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
GlimepirideCiprofloxacin
Severe

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Co-administration of Dioglip Plus 15mg/1mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Dioglip Plus 15mg/1mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without a doctor's advice.
GlimepirideCiprofloxacin
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Taking ciprofloxacin with Dioglip Plus 15mg/1mg Tablet can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and Dioglip Plus 15mg/1mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideNalidixic acid
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
When Dioglip Plus 15mg/1mg Tablet is taken with Nalidixic acid, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
There may be a possibility of interaction between Dioglip Plus 15mg/1mg Tablet and Nalidixic acid, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
GlimepirideMiconazole
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Co-administration of Miconazole with Dioglip Plus 15mg/1mg Tablet may increase the blood levels and effects of Dioglip Plus 15mg/1mg Tablet leading to low blood glucose levels.

How to manage the interaction:
Although there is a possible interaction between Miconazole and Dioglip Plus 15mg/1mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat Consult a doctor immediately. Do not stop using medications without a doctor's advice.
GlimepirideKetoprofen
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Taking Ketoprofen with Dioglip Plus 15mg/1mg Tablet may increase the risk of hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is a possible interaction, Dioglip Plus 15mg/1mg Tablet can be taken with Ketoprofen if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
GlimepirideSunitinib
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Taking Dioglip Plus 15mg/1mg Tablet with sunitinib may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Dioglip Plus 15mg/1mg Tablet can be taken with sunitinib if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideGrepafloxacin
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Co-administration of Dioglip Plus 15mg/1mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is a possible interaction between Dioglip Plus 15mg/1mg Tablet and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideMoxifloxacin
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Co-administration of Moxifloxacin can affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Dioglip Plus 15mg/1mg Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience headache, dizziness, rapid heartbeat, increased thirst, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideClarithromycin
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
Taking Clarithromycin with Dioglip Plus 15mg/1mg Tablet may increase the effects of Dioglip Plus 15mg/1mg Tablet on lowering blood sugar.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Dioglip Plus 15mg/1mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, hunger, weakness, dizziness, drowsiness, nervousness, sweating, confusion, and tremor. Do not discontinue the medications without consulting a doctor.
GlimepiridePromazine
Severe
How does the drug interact with Dioglip Plus 15mg/1mg Tablet:
When Dioglip Plus 15mg/1mg Tablet is taken with Promazine may interfere with blood glucose control and reduce the effectiveness of Dioglip Plus 15mg/1mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Dioglip Plus 15mg/1mg Tablet and Promazine, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • RIFAMPICIN
  • COLESEVELAM
  • METOPROLOL
  • PROPRANOLOL
  • TIMOLOL

Habit Forming

No

Special Advise

  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice. 
  • Take short frequent meals, avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • It is always better that your physician knows about any underlying conditions like kidney disease or liver disease, prior heart attack, alcohol intake, etc before the doctor prescribes you this medicine.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar, etc.

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins and a quarter with whole grains.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Dioglip Plus 15mg/1mg Tablet Substitute

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