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  3. Divagrace 500 Tablet 10's

Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

DIVALPROEX-500MG

Manufacturer/Marketer :

Cyrus Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

India
Other Info - DIV0299

FAQs

Divagrace 500 Tab decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Divagrace 500 Tab helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Divagrace 500 Tab limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Divagrace 500 Tab may interact with aspirin and cause abnormal side-effects. So, it is recommended to take any medication along with Divagrace 500 Tab only after consulting a doctor.

Divagrace 500 Tab may improve the symptoms of depression. However, do not use it without consulting a doctor as it may also cause mood disturbances and suicidal thoughts in some patients.

Do not discontinue Divagrace 500 Tab without consulting your doctor. To treat your condition effectually, continue taking Divagrace 500 Tab for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Divagrace 500 Tab ; your doctor will gradually reduce the dose to avoid worsening seizures.

Divagrace 500 Tab may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Divagrace 500 Tab may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Divagrace 500 Tab .

Topiramate (anticonvulsant) should not be taken along with Divagrace 500 Tab as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Divagrace 500 Tab as it may cause increased dizziness.

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Pregnancy

Unsafe

Divagrace 500 Tab belongs to pregnancy category D. Avoid taking Divagrace 500 Tab if you are pregnant as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Divagrace 500 Tab may pass into breastmilk. Consult your doctor before taking Divagrace 500 Tab if you are breastfeeding.

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Driving

Unsafe

Divagrace 500 Tab causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

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Liver

Caution

Divagrace 500 Tab should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Divagrace 500 Tab can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below two years as they are at a higher risk of liver toxicity.

About Divagrace 500 Tab

Divagrace 500 Tab belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Divagrace 500 Tab is also used to treat manic episodes associated with bipolar disorder and prevent migraines. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Divagrace 500 Tab contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Divagrace 500 Tab increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder. 

Take Divagrace 500 Tab with or without food. Depending on your medical condition, you are advised to take Divagrace 500 Tab for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side-effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Divagrace 500 Tab without consulting your doctor to avoid worsening seizures. Do not take Divagrace 500 Tab if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Divagrace 500 Tab . Consult your doctor before taking Divagrace 500 Tab if you are breastfeeding. Avoid driving or operating machinery as Divagrace 500 Tab causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Divagrace 500 Tab as it could lead to increased dizziness. Care should be taken while giving Divagrace 500 Tab to children below two years as there is a higher risk of liver intoxication during the first 6months of treatment. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Divagrace 500 Tab

Epilepsy, bipolar disorder, migraine

Medicinal Benefits Mweb

Medicinal Benefits

Divagrace 500 Tab belongs to a group of medicines called anticonvulsants or anti-epileptics. Divagrace 500 Tab is used to treat epilepsy/seizures/fits. Also, Divagrace 500 Tab is used to treat mood disorders and prevent migraine headaches. Divagrace 500 Tab decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures. Divagrace 500 Tab treats mood disorders by increasing the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Divagrace 500 Tab prevents migraine headaches by limiting the transmission of nerve pain. Divagrace 500 Tab is used alone or in combination to treat simple, complex partial, and complex absence seizures. Divagrace 500 Tab is used in combination to treat multiple seizures, such as absence seizures.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush it.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Sprinkle capsule: Swallow it as a whole with water or sprinkle the capsule contents on food and consume.

Side Effects of Divagrace 500 Tab

  • Abdominal pain
  • Back pain
  • Constipation
  • Diarrhoea
  • Dizziness
  • Nausea
  • Increased appetite
  • Vomiting
  • Vision problems
  • Weight changes
  • Problems with walking or coordination

Drug Warnings

Do not take Divagrace 500 Tab if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Divagrace 500 Tab if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Divagrace 500 Tab . Divagrace 500 Tab may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Divagrace 500 Tab without consulting your doctor to avoid worsening of seizures. Do not take Divagrace 500 Tab if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Divagrace 500 Tab . Consult your doctor before taking Divagrace 500 Tab if you are breastfeeding. Avoid driving or operating machinery as Divagrace 500 Tab causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Divagrace 500 Tab as it could lead to increased dizziness. Care should be taken while giving Divagrace 500 Tab to children below 2 years as there is a higher risk of liver intoxication during the first six months of treatment.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Divagrace 500 Tablet:
Coadministration of Glycerol phenylbutyrate and Divagrace 500 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Divagrace 500 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Divagrace 500 Tablet:
Coadministration of Ertapenem with Divagrace 500 Tablet may reduce the blood levels of Divagrace 500 Tablet and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Divagrace 500 Tablet if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexEsketamine
Severe
How does the drug interact with Divagrace 500 Tablet:
Coadministration of Esketamine and Divagrace 500 Tablet can increase the side effects of esketamine.

How to manage the interaction:
Although taking Divagrace 500 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexBexarotene
Severe
How does the drug interact with Divagrace 500 Tablet:
Co-administration of Divagrace 500 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Divagrace 500 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Divagrace 500 Tablet:
Co-administration of Divagrace 500 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divagrace 500 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexLomitapide
Severe
How does the drug interact with Divagrace 500 Tablet:
Co-administration of Divagrace 500 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divagrace 500 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Divagrace 500 Tablet:
Co-administration of Divagrace 500 Tablet and Meropenem can reduce the blood levels of Divagrace 500 Tablet sodium.

How to manage the interaction:
Co-administration of Divagrace 500 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Divagrace 500 Tablet:
Co-administration of buprenorphine with Divagrace 500 Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Divagrace 500 Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexSodium oxybate
Severe
How does the drug interact with Divagrace 500 Tablet:
Co-administration of Sodium oxybate and Divagrace 500 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Divagrace 500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Divagrace 500 Tablet:
Coadministration of Ketoconazole and Divagrace 500 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Divagrace 500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • PREGABALIN
  • TOPIRAMATE
  • PHENOBARBITAL
  • PRIMIDONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ETHOSUXIMIDE
  • ZIDOVUDINE
  • DULOXETINE
  • ESCITALOPRAM
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • ALPRAZOLAM
  • RIFAMPICIN
  • WARFARIN
  • IMIPENEM
  • MEROPENEM
  • DIAZEPAM

Habit Forming

No

Special Advise

  • Regular monitoring of blood count and coagulation tests are advised while taking Divagrace 500 Tab as it may cause thrombocytopenia (low platelet levels).
  • Divagrace 500 Tab may cause liver toxicity, usually during the first 6months of treatment. Children below two years are at a higher risk. Regular monitoring of liver function tests before treatment and at frequent intervals is advised.
  • Divagrace 500 Tab might alter thyroid function tests and urine ketone tests. Inform the person doing the tests that you are taking Divagrace 500 Tab .

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, help those around you know what to do.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

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