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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PIROXICAM-40MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANALGESICS

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - DOL0005

Author Details

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FAQs

Dolonex 40 mg IM Injection 5 x 2 ml works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side-effect of Dolonex 40 mg IM Injection 5 x 2 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not use Dolonex 40 mg IM Injection 5 x 2 ml immediately before or after bypass surgery. Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of heart attack or stroke. Therefore, inform your doctor if you have heart problems.

Dolonex 40 mg IM Injection 5 x 2 ml may be used to treat musculoskeletal pain. Musculoskeletal pain refers to the pain in the bones, muscles, ligaments, and tendon.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Dolonex 40 mg IM Injection 5 x 2 ml. Alcohol intake, along with Dolonex 40 mg IM Injection 5 x 2 ml, may cause increased dizziness. It may also increase the risk of stomach/intestine ulcers and bleeding.

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Pregnancy

Caution

Avoid taking Dolonex 40 mg IM Injection 5 x 2 ml if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Dolonex 40 mg IM Injection 5 x 2 ml only if the benefits outweigh the risks. Do not take Dolonex 40 mg IM Injection 5 x 2 ml in the last 20 weeks of pregnancy as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dolonex 40 mg IM Injection 5 x 2 ml. Please consult your doctor if you have any concerns.

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Driving

Caution

Dolonex 40 mg IM Injection 5 x 2 ml may cause dizziness. Do not drive or operate heavy machinery if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Dolonex 40 mg IM Injection 5 x 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Dolonex 40 mg IM Injection 5 x 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dolonex 40 mg IM Injection 5 x 2 ml is not recommended for children, as the efficacy and safety have not been established.

About Dolonex 40 mg IM Injection 5 x 2 ml

Dolonex 40 mg IM Injection 5 x 2 ml belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Dolonex 40 mg IM Injection 5 x 2 ml contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Dolonex 40 mg IM Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of heart attack and the chances of stomach ulcers and bleeding. If you have had any recent heart bypass surgery, do not take Dolonex 40 mg IM Injection 5 x 2 ml unless prescribed by the doctor. Consult your doctor before taking Dolonex 40 mg IM Injection 5 x 2 ml if you are pregnant or breastfeeding. Dolonex 40 mg IM Injection 5 x 2 ml may cause dizziness, so drive with caution. Dolonex 40 mg IM Injection 5 x 2 ml is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Dolonex 40 mg IM Injection 5 x 2 ml as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of Dolonex 40 mg IM Injection 5 x 2 ml

Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis

Medicinal Benefits Mweb

Medicinal Benefits

Dolonex 40 mg IM Injection 5 x 2 ml belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain. It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. Dolonex 40 mg IM Injection 5 x 2 ml works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Directions for Use

Dolonex 40 mg IM Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer.

Side Effects of Dolonex 40 mg IM Injection 5 x 2 ml

  • Injection site reactions
  • Diarrhoea
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain

Drug Warnings

Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Dolonex 40 mg IM Injection 5 x 2 ml. Besides this, Dolonex 40 mg IM Injection 5 x 2 ml may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take Dolonex 40 mg IM Injection 5 x 2 ml if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack. Consult your doctor before taking Dolonex 40 mg IM Injection 5 x 2 ml if you are pregnant or breastfeeding. Dolonex 40 mg IM Injection 5 x 2 ml may cause dizziness, so drive only if you are alert. Dolonex 40 mg IM Injection 5 x 2 ml is not recommended for children as safety has not been established. Avoid consuming alcohol along with Dolonex 40 mg IM Injection 5 x 2 ml as it could lead to increased dizziness and may increase the risk of stomach bleeding. Inform your doctor before taking Dolonex 40 mg IM Injection 5 x 2 ml if you have asthma, water retention (oedema) or high blood pressure, stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Using ketorolac tromethamine together with Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of side effects.

How to manage the interaction:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Co-administration of Cidofovir with Dolonex 40 mg IM Injection 5 x 2 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamDesirudin
Severe
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with Desirudin together can increase the risk of bleeding.

How to manage the interaction:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with Meloxicam together can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Dolonex 40 mg IM Injection 5 x 2 ml and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Using panobinostat together with Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Dolonex 40 mg IM Injection 5 x 2 ml and Panobinostat, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Using acalabrutinib together with Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of bleeding.

How to manage the interaction:
Although taking Dolonex 40 mg IM Injection 5 x 2 ml and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Taking Dolonex 40 mg IM Injection 5 x 2 ml with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Fondaparinux and Dolonex 40 mg IM Injection 5 x 2 ml, you can take these medicines together if prescribed by a doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Using regorafenib together with Dolonex 40 mg IM Injection 5 x 2 ml may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Dolonex 40 mg IM Injection 5 x 2 ml and Regorafenib, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Coadministration of Naproxen and Dolonex 40 mg IM Injection 5 x 2 ml can increase the risk or severity of stomach bleeding, inflammation(swelling with redness and pain), ulcers.

How to manage the interaction:
There may be a possible interaction between Naproxen and Dolonex 40 mg IM Injection 5 x 2 ml, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Dolonex 40 mg IM Injection 5 x 2 ml:
Coadministration of Dolonex 40 mg IM Injection 5 x 2 ml and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although taking Ketoconazole and Dolonex 40 mg IM Injection 5 x 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • METOPROLOL
  • CELECOXIB

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

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