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  3. Dorpivib 500 Injection

Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

DORIPENEM-500MG

Manufacturer/Marketer :

Vibcare Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India

Manufacturer/Marketer address

SCO 42, 1st Floor, Swastic Vihar, Mansa Devi Complex, Sector 5, Panchkula, Haryana 134109, India
Other Info - DO99469

FAQs

Dorpivib 500 Injection contains doripenem. Doripenem is an antibacterial drug. It works by killing bacteria. Thus, Dorpivib 500 Injection helps treat bacterial infections.

Caution should be exercised. Patients with seizure disorders who are being treated with valproic acid or sodium valproate are at a higher risk of having a seizure. It has been demonstrated that administering Dorpivib 500 Injection together with valproic acid lowers its (valproic acid) serum levels.

In some cases, Dorpivib 500 Injection may lead to Clostridium difficile-associated diarrhoea (ranging from mild to fatal colitis): in major cases, it gradually resolves over time. In case this condition persists, consult your doctor immediately.

Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.

To reduce the development of antibiotic resistance and maintain the effectiveness of Dorpivib 500 Injection, it should only be used to treat or prevent infections that are proven or highly suspected to be caused by bacteria.

Usually, Dorpivib 500 Injection starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

Disclaimer

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Alcohol

Caution

Consuming alcohol with Dorpivib 500 Injection is not advisable as it may cause unpleasant side effects.

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Pregnancy

Consult your doctor

Please visit your doctor. There are no adequate and well-controlled studies in pregnant women. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor; there has been no significant research on the use of Dorpivib 500 Injection in breastfeeding women.

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Driving

Caution

It is unclear whether Dorpivib 500 Injection affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

Limited information was available about using Dorpivib 500 Injection in patients with liver disease. Inform your doctor before receiving Dorpivib 500 Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving Dorpivib 500 Injection if you have had a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

It is not recommended for use in children below 18 years.

About Dorpivib 500 Injection

Dorpivib 500 Injection belongs to the group of antibiotic medicines called carbapenems. It is indicated in treating bacterial infections such as complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis). Bacterial infections are illnesses or conditions caused by bacterial growth or toxins (poisons).

Dorpivib 500 Injection contains doripenem. Doripenem is an antibacterial drug. It works by inhibiting bacterial enzymes called penicillin-binding proteins (PBPs) and shows a bactericidal effect. Thus, Dorpivib 500 Injection treats bacterial infections.

Dorpivib 500 Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Dorpivib 500 Injection may cause injection site reactions, headaches, nausea, diarrhoea, rash, and phlebitis (vein inflammation). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, consult your doctor.

Inform your doctor if you are allergic to any component in Dorpivib 500 Injection. If you are pregnant or breastfeeding, inform your doctor before taking Dorpivib 500 Injection. It is not recommended for use in children below 18 as safety and effectiveness have not been established. Keep your doctor up to date on your medical condition and medications to rule out any potential adverse effects or interactions.

Uses of Dorpivib 500 Injection

Bacterial infections (Complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis).

Medicinal Benefits Mweb

Medicinal Benefits

Dorpivib 500 Injection contains doripenem. Doripenem is an antibacterial drug. It works by killing bacteria. Thus, Dorpivib 500 Injection helps treat bacterial infections. It is indicated in treating bacterial infections such as complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis).

Directions for Use

A healthcare professional will administer Dorpivib 500 Injection. Do not self-administer.

Side Effects of Dorpivib 500 Injection

  • Redness, pain, or swelling at the injection site
  • Headaches
  • Nausea
  • Diarrhoea
  • Rash
  • Phlebitis (vein inflammation)

Drug Warnings

Dorpivib 500 Injection is contraindicated in patients with known serious hypersensitivity to doripenem, other drugs in the same class, or patients who have demonstrated anaphylactic reactions to beta-lactams. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Dorpivib 500 Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. If symptoms worsen or persist or new symptoms appear, patients should stop using the medicine and consult a doctor. Valproic acid lowers serum valproic acid concentrations. Patients with seizure disorders treated with valproic acid or sodium valproate are at a higher risk of having a seizure.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dorpivib 500 Injection:
Co-administration of Divalproex and Dorpivib 500 Injection can reduce the blood levels of divalproex sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Divalproex with Dorpivib 500 Injection can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dorpivib 500 Injection:
Co-administration of sodium valproate with Dorpivib 500 Injection can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and sodium valproate can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • VALPROIC ACID
  • DIVALPROEX SODIUM

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Dorpivib 500 Injection to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Dorpivib 500 Injection.
  • Avoid intake of alcoholic beverages with Dorpivib 500 Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Dorpivib 500 Injection in fighting off infections.

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