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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dotin M 75mg/1500mcg Tablet

Dotin M 75mg/1500mcg Tablet belongs to the class of medications called antidepressants used in the treatment of depression. Depression is a neurological disease. It is a mood disorder characterized by persistent feelings of sadness, loss, or anger. This condition can also be triggered by vitamin b12 deficiency. Your doctor prescribes Dotin M 75mg/1500mcg Tablet when other medications are ineffective to treat depression. 

Dotin M 75mg/1500mcg Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Dosulepin is a tricyclic antidepressant that increases neurotransmitter's activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

The dose is determined by your doctor based on your health condition. The common side-effects of Dotin M 75mg/1500mcg Tablet are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.

Do not take Dotin M 75mg/1500mcg Tablet if you are allergic to any content of it. Do not take Dotin M 75mg/1500mcg Tablet if you have an irregular heartbeat or any other heart problems, liver problems, eye condition known as glaucoma, prostate problems in men (difficulty in passing water or enlarged prostate), mania (feeling over-excited with unusual behaviour), and epilepsy (fits). It should be used with caution in young adults as it can increase worsen depression and cause suicidal thoughts. If you have thoughts of harming yourself, consult your doctor immediately. Inform your doctor if you are pregnant or breastfeeding. 

Uses of Dotin M 75mg/1500mcg Tablet

Depression

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Dotin M 75mg/1500mcg Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Your doctor prescribes this medication when other medications are ineffective to treat depression. Dosulepin is a tricyclic antidepressant that increases neurotransmitters' activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Dotin M 75mg/1500mcg Tablet, inform your doctor if you are undergoing surgery, have diabetes, receiving electroshock therapy (ECT), have thyroid problems, difficulty in passing urine, adrenal gland tumour, have porphyria (disease-causing damage to the nerves and skin sensitivity), have a history of mania or psychosis, have cardiac disease, have severe renal disease, and have epilepsy (fits). It increases suicidal tendencies, especially in young adults.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Amitriptyline and Dotin M 75mg/1500mcg Tablet may increase the risk of irregular heartbeat. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although combining Amitriptyline with Dotin M 75mg/1500mcg Tablet may result in an interaction, it can be used when a doctor recommends it. If you experience sudden dizziness or irregular heartbeats during therapy, contact your doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of paroxetine and Dotin M 75mg/1500mcg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Dotin M 75mg/1500mcg Tablet and paroxetine together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, increased heart rate, fever, excessive sweating, blurred vision, muscle spasms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Dotin M 75mg/1500mcg Tablet with Chloramphenicol can impair absorption and increase the levels of Dotin M 75mg/1500mcg Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dotin M 75mg/1500mcg Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Dotin M 75mg/1500mcg Tablet with Neomycin can impair the absorption of Dotin M 75mg/1500mcg Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dotin M 75mg/1500mcg Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced diet.
  • Avoid processed or packed foods and foods that are high in refined sugars.
  • Exercise regularly.
  • Lose excess weight and keep a check on your weight.
  • Avoid stress.
  • Improve your mood by being active, socializing with others, and talking about your feelings.
  • Quit alcohol intake and smoking.

 

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Dotin M 75mg/1500mcg Tablet Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dotin M 75mg/1500mcg Tablet contains Dosulepin and Methylcobalamin. It treats depression by enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. It also treats vitamin B12 deficiency which is a risk factor for depression.

Dotin M 75mg/1500mcg Tablet should not be used in patients with heart problems as it may worsen the condition. Discuss with your doctor about the potential benefits and risks before using Dotin M 75mg/1500mcg Tablet.

The common side-effects of Dotin M 75mg/1500mcg Tablet are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.

Dotin M 75mg/1500mcg Tablet should not be used in patients with thyroid problems as it may exacerbate the condition by causing iatrogenic effects (drug-inducing side-effects). So, discuss the risks and benefits of this medication with your doctor before using Dotin M 75mg/1500mcg Tablet.

Dotin M 75mg/1500mcg Tablet increases suicidal thoughts and worsens the depression in young adults. Your doctor may prescribe this medicine with dose adjustments. So, do not use Dotin M 75mg/1500mcg Tablet without consulting your doctor.

Drug-Drug Interactions Checker List

  • OMEPRAZOLE
  • CIMETIDINE
  • HALOFANTRINE
  • TERFENADINE
  • ASTEMIZOLE
  • TRAMADOL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • WARFARIN
  • RITONAVIR
  • NEOMYCIN
  • RIFAMPICIN

Disease/Condition Glossary

Depression: Depression is a mental health disorder in which patients experience persistent loss of interest or mood and feelings of sadness. It affects quality-of-life. It causes changes in sleep, appetite, social behaviour, learning abilities, concentration, and self-esteem. This condition can also be triggered by vitamin B12 (cyanocobalamin) deficiency.

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