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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Psychotropics India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Drotapil Plus 80 mg/500 mg Tablet

Drotapil Plus 80 mg/500 mg Tablet belongs to the class of medicine called 'antispasmodic' combined with a painkiller, used to reduce and relieve abdominal pain and muscle spasms in the gastrointestinal tract, urinary tract and gall bladder. Abdominal (tummy) pain occurs between your chest and pelvic region (below the belly button and leg). 

Drotapil Plus 80 mg/500 mg Tablet is a combination of two drugs: Drotaverine (antispasmodic) and Paracetamol (pain killer). Drotaverine works by relieving contractions (spasms) associated with smooth muscles of the abdomen. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotapil Plus 80 mg/500 mg Tablet helps in relieving abdominal pain and cramps.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Drotapil Plus 80 mg/500 mg Tablet include dry mouth, feeling thirsty, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications, including other vitamins, before starting Drotapil Plus 80 mg/500 mg Tablet. Inform your doctor if you have any liver, heart or kidney diseases and alcohol dependency before taking Drotapil Plus 80 mg/500 mg Tablet. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Drotapil Plus 80 mg/500 mg Tablet. Drotapil Plus 80 mg/500 mg Tablet may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Drotapil Plus 80 mg/500 mg Tablet as it could lead to increased dizziness and risk of liver damage. Drotapil Plus 80 mg/500 mg Tablet should not be given to children below one year of age as safety has not been established.

Uses of Drotapil Plus 80 mg/500 mg Tablet

Abdominal pain and cramps.

Directions for Use

Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Drotapil Plus 80 mg/500 mg Tablet consists of Drotaverine (antispasmodic) and Paracetamol (pain killer). It relieves abdominal pain, and muscle spasms in the gastrointestinal tract, urinary tract and gall bladder. Drotaverine works by reducing contractions (spasms) associated with smooth muscles of the abdomen. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotapil Plus 80 mg/500 mg Tablet helps in relieving abdominal pain and cramps.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Let your doctor know if you use any prescription and non-prescription medications, including other vitamins, before starting Drotapil Plus 80 mg/500 mg Tablet. Inform your doctor if you have any liver, heart or kidney diseases and alcohol dependency. Drotapil Plus 80 mg/500 mg Tablet may cause fluid retention (oedema); hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history. Do not take Drotapil Plus 80 mg/500 mg Tablet if you are breastfeeding. Please consult your doctor know if you are pregnant and planning to conceive. Avoid consuming alcohol along with Drotapil Plus 80 mg/500 mg Tablet as it could lead to increased dizziness and risk of liver damage. Drotapil Plus 80 mg/500 mg Tablet is not recommended in children below one year of age.

Drug-Drug Interactions

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ParacetamolValdecoxib
Severe

Drug-Drug Interactions

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ParacetamolValdecoxib
Severe
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Drotapil Plus 80 mg/500 mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Drotapil Plus 80 mg/500 mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Drotapil Plus 80 mg/500 mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Drotapil Plus 80 mg/500 mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Drotapil Plus 80 mg/500 mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Drotapil Plus 80 mg/500 mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Teriflunomide with Drotapil Plus 80 mg/500 mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Drotapil Plus 80 mg/500 mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of ketamine and Drotapil Plus 80 mg/500 mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Drotapil Plus 80 mg/500 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Drotapil Plus 80 mg/500 mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Drotapil Plus 80 mg/500 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Lomitapide and Drotapil Plus 80 mg/500 mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Drotapil Plus 80 mg/500 mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Drotapil Plus 80 mg/500 mg Tablet:
Co-administration of Mipomersen with Drotapil Plus 80 mg/500 mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Drotapil Plus 80 mg/500 mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS/SPASMOLYTIC ANALGESICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drotapil Plus 80 mg/500 mg Tablet is a combination of two drugs: Drotaverine and Paracetamol. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

Drotapil Plus 80 mg/500 mg Tablet may cause dizziness. So, drive only if you are alert and avoid driving or operating machinery if you feel dizzy.

Drotapil Plus 80 mg/500 mg Tablet is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

Drotapil Plus 80 mg/500 mg Tablet is to be carefully administered in patients with alcohol dependency or a history of kidney or liver damage. Please consult your doctor before starting Drotapil Plus 80 mg/500 mg Tablet if you have a medical history.

Drug-Drug Interactions Checker List

  • WARFARIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • LEVODOPA

Special Advise

  • Let your doctor know that you are taking Drotapil Plus 80 mg/500 mg Tablet if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since Drotaverine in Drotapil Plus 80 mg/500 mg Tablet may lower your blood pressure.
  • Drotapil Plus 80 mg/500 mg Tablet may cause fluid retention (oedema); hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders and obstruction/blockage.

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