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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Composition :

NORETHISTERONE-5MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dubfree Tablet

Dubfree Tablet belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Dubfree Tablet may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Dubfree Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take Dubfree Tablet as prescribed by your doctor. You are advised to take Dubfree Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhea, headache, breast pain, and tenderness. Most of these side effects of Dubfree Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dubfree Tablet or any other medicines, please tell your doctor. Dubfree Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Dubfree Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Dubfree Tablet. You are advised to stop smoking while taking Dubfree Tablet as it may increase the risk of adverse effects.

Uses of Dubfree Tablet

Heavy, painful or irregular periods, Premenstrual syndrome (PMS), Endometriosis, Breast cancer

Directions for Use

Take Dubfree Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Dubfree Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Keep Dubfree Tablet out of reach and sight of children.

Drug Warnings

If you are allergic to Dubfree Tablet or any other medicines, please tell your doctor. Dubfree Tablet is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking Dubfree Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Dubfree Tablet. You are advised to stop smoking while taking Dubfree Tablet as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking Dubfree Tablet as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Dubfree Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneAmprenavir
Severe

Drug-Drug Interactions

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NorethisteroneAmprenavir
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Amprenavir and Dubfree Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Dubfree Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Dubfree Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dubfree Tablet:
Taking Dubfree Tablet with rifampicin can decrease the blood levels of Dubfree Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dubfree Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Dubfree Tablet:
Using Etretinate and Dubfree Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Dubfree Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneTelaprevir
Severe
How does the drug interact with Dubfree Tablet:
Using Telaprevir and Dubfree Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Dubfree Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dubfree Tablet:
Coadministration of Phenytoin and Dubfree Tablet may decrease the blood levels of Dubfree Tablet, which may make Dubfree Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Dubfree Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dubfree Tablet:
Co-administration of Dubfree Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Dubfree Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet with Oxcarbazepine can reduce the blood levels and effects of norethindrone. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking oxcarbazepine and Dubfree Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet and Mycophenolic acid can decrease the levels and effects of Dubfree Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Dubfree Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Dubfree Tablet:
Taking griseofulvin with Dubfree Tablet may reduce blood levels and the effects of Dubfree Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Dubfree Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Dubfree Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Dubfree Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Dubfree Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dubfree Tablet contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Dubfree Tablet may be used to delay periods. Dubfree Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Dubfree Tablet.

Dubfree Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Dubfree Tablet.

You are not recommended to take Dubfree Tablet with rifampicin as it may decrease the levels of Dubfree Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Dubfree Tablet with other medicines.

Periods usually resume within 3 days of discontinuing Dubfree Tablet. However, please consult a doctor if you have any concerns regarding this.

Dubfree Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Dubfree Tablet and inform your doctor if you have diabetes before taking Dubfree Tablet.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • NELFINAVIR
  • RITONAVIR
  • AMINOGLUTETHIMIDE
  • COTRIMOXAZOLE
  • RIFAMPICIN
  • TETRACYCLINE
  • CICLOSPORIN

Special Advise

  • Dubfree Tablet may interfere with certain laboratory tests. Therefore, inform your doctor that you are taking Dubfree Tablet before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse, or discomfort with bowel movements. 

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