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  1. Home
  2. Medicine

  3. Duovir Tablet 60's

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Written By ,
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
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Duovir Tablet 60's, Pack of 1 TABLET
Duovir Tablet 60's, Pack of 1 TABLET
Duovir Tablet 60's, Pack of 1 TABLET
Duovir Tablet 60's, Pack of 1 TABLET
rxMedicinePrescription drug

Whats That

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Composition :

LAMIVUDINE-150MG + ZIDOVUDINE-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRETROVIRAL AGENTS

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DUO0037

FAQs

Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Duovir Tablet should be used with proper caution and doctor consultation if you have kidney disease, liver disease, pancreatic disease, low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Stopping Duovir Tablet may increase the risk of treatment failure. So Duovir Tablet should not be stopped without consulting your doctor.

Please consult your doctor if you are using other medicines before starting Duovir Tablet . However, medicines like didanosine, co-trimoxazole, clarithromycin, fluconazole, rifampicin, ranitidine, and phenytoin may interact with Duovir Tablet and should not be used simultaneously.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Duovir Tablet with alcohol can cause unpleasant side effects. So please consult your doctor before consumption of alcohol while taking Duovir Tablet .

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Pregnancy

Caution

Duovir Tablet is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Breast Feeding

Caution

Duovir Tablet is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or breastfeeding based on your clinical condition.

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Driving

Caution

Duovir Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.

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Liver

Caution

Duovir Tablet should be used with caution in liver patients due to the increased risk of worsening the patient's condition. So please consult your doctor before taking Duovir Tablet .

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Kidney

Caution

Duovir Tablet should be used with caution in kidney patients due to the increased risk of serious side effects. So please consult your doctor before taking Duovir Tablet .

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Children

Caution

Duovir Tablet should be used with caution in Children. Your doctor may prescribe Duovir Tablet by adjusting the dose based on the height and weight of the children.

Product Substitutes

Lazid Tablet 60's

Lazid Tablet 60's

₹1275.3

MRP ₹1417

Duovir Tablet 10's

Duovir Tablet 10's

₹193.95

MRP ₹215.5

VIROCOMB FC 150MG TABLET

VIROCOMB FC 150MG TABLET

₹1112.94

MRP ₹1236.6

ZIDOVEX L TABLET

ZIDOVEX L TABLET

₹57.51

MRP ₹63.9

Zovilam 150mg/300mg Tablet

Zovilam 150mg/300mg Tablet

₹1120.5

MRP ₹1245

Reference

  1. https://www.mims.com/malaysia/drug/info/lamivudine%20+%20zidovudine?mtype=generic
  2. https://www.medicines.org.uk/emc/product/2998/smpc#PRODUCTINFO
  3. https://www.webmd.com/drugs/2/drug-4666/lamivudine-zidovudine-oral/details
  4. https://www.drugs.com/mtm/lamivudine-and-zidovudine.html
  5. https://www.drugs.com/mtm/lamivudine-and-zidovudine.html

About Duovir Tablet

Duovir Tablet belongs to the class of medicines called 'anti-retroviral agents', used for the treatment of immunodeficiency virus (HIV) infection. HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body.

Duovir Tablet contains lamivudine and zidovudine. Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Take Duovir Tablet as advised by your doctor. Duovir Tablet may cause common side effects like nausea, diarrhoea, headache, fatigue, cough, a feeling of discomfort, and nasal congestion (stuffy nose). Most of these side effects gradually resolve over time and do not require medical attention. However, if these side effects persist or worsen, please consult your doctor immediately.

Inform your doctor if you are allergic to any of the components in Duovir Tablet . Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, or pancreatic disease. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Uses of Duovir Tablet

Human immunodeficiency virus (HIV) infection.

Medicinal Benefits Mweb

Medicinal Benefits

Duovir Tablet contains a combination of two medicines, namely: lamivudine and zidovudine, that belong to the group of medications called anti-retroviral agents. Duovir Tablet is primarily used for the treatment of human immunodeficiency virus (HIV) infection. Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Directions for Use

Swallow Duovir Tablet as a whole with a glass of water. Do not chew, crush or break it.

Side Effects of Duovir Tablet

  • Nausea
  • Diarrhoea
  • Stomach pain
  • Loss of appetite
  • Tiredness
  • Lack of energy
  • Fever (high temperature)
  • Headache
  • Hair loss (alopecia)
  • Fatigue
  • Cough
  • Muscle pain and discomfort
  • Joint pain
  • Feeling of discomfort
  • Difficulty in sleeping (insomnia)
  • Irritated or runny nose

Drug Warnings

Inform your doctor if you are allergic to any of the components in Duovir Tablet . Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, pancreatic, or bone marrow suppression. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis, or opportunistic infections. Duovir Tablet may cause muscle disorders, especially when used for a long period. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
LamivudineLeflunomide
Severe

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Duovir Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Duovir Tablet:
Combining Duovir Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineMipomersen
Severe
How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Duovir Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
LamivudineTeriflunomide
Severe
How does the drug interact with Duovir Tablet:
Teriflunomide can cause Duovir Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineZalcitabine
Severe
How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineBexarotene
Severe
How does the drug interact with Duovir Tablet:
Taking bexarotene together with Duovir Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Duovir Tablet:
Duovir Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Duovir Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
LamivudineLomitapide
Severe
How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
ZidovudineValganciclovir
Severe
How does the drug interact with Duovir Tablet:
Combining Valganciclovir with Duovir Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Valganciclovir and Duovir Tablet together can cause an interaction, it can be taken if your doctor has suggested it. If you experience any complications or symptoms, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ZidovudineInfliximab
Severe
How does the drug interact with Duovir Tablet:
When Duovir Tablet and Infliximab are taken together, the body breaks down Duovir Tablet faster. This can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Duovir Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods
Mild

Drug-Food Interactions

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LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Consuming high-fat foods along with Duovir Tablet may decrease its effectiveness. Avoid or limit the consumption of high-fat foods with Duovir Tablet as it can increase the risk of side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIDANOSINE
  • EFAVIRENZ
  • ATOVAQUONE
  • CLARITHROMYCIN
  • GANCICLOVIR
  • COTRIMOXAZOLE
  • FLUCONAZOLE
  • RIFAMPICIN
  • PHENOBARBITAL
  • PHENYTOIN
  • VALPROIC ACID
  • RANITIDINE
  • CIMETIDINE
  • CLADRIBINE
  • PROBENECID
  • METHOTREXATE
  • ATORVASTATIN
  • FENOFIBRATE
  • CLOZAPINE

Habit Forming

No

Special Advise

  • Skipping doses of Duovir Tablet may increase the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Always practice safe sex while taking Duovir Tablet . Do not share needles or personal items that can have blood or body fluids on them.
  • Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor because Duovir Tablet may cause the weakening of your bones.

Diet & Lifestyle Advise

  • Take a diet high in vegetables, fruits, whole grains, and legumes.
  • Choose lean, low-fat sources of protein.
  • Limit sweets, soft drinks, and foods with added sugar. 
  • Take proteins, carbohydrates, and a good little fat in all meals and snacks in your regular diet.
  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly.
  • Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Exercise regularly. 
  • Avoid excessive alcohol and quit smoking.

Duovir Tablet Substitute

Substitutes safety advice

  • Lazid Tablet 60's

    by Others

    ₹21.25per tablet

  • Duovir Tablet 10's

    by Others

    ₹19.39per tablet

  • VIROCOMB FC 150MG TABLET

    by Others

    ₹18.55per tablet

  • ZIDOVEX L TABLET

    by Others

    ₹19.17per tablet

  • Zovilam 150mg/300mg Tablet

    by Others

    ₹18.68per tablet
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