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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

Therapeutic Class

[ANTIVIRALS]

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - DUR0251

Author Details

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FAQs

DURATAF 25MG TABLET contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.

No, DURATAF 25MG TABLET is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.

DURATAF 25MG TABLET should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.

A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Avoid drinking alcohol. Consuming alcohol while using DURATAF 25MG TABLET may worsen the condition.

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Pregnancy

Consult your doctor

DURATAF 25MG TABLET is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take DURATAF 25MG TABLET without the doctor's advice.

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Breast Feeding

Consult your doctor

Consult your doctor, and there is no substantial research yet on the use of DURATAF 25MG TABLET in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

DURATAF 25MG TABLET can cause dizziness. If you feel dizzy when taking DURATAF 25MG TABLET , do not drive and use any tools or machines.

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Liver

Consult your doctor

Consult your doctor before taking DURATAF 25MG TABLET if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Kidney

Consult your doctor

Consult your doctor before taking DURATAF 25MG TABLET if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Safe if prescribed

Should not use DURATAF 25MG TABLET in children below 12 years of age.

About DURATAF 25MG TABLET

DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take DURATAF 25MG TABLET as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of DURATAF 25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using DURATAF 25MG TABLET as it may cause dizziness, affecting your ability to drive or use machines. Should not use DURATAF 25MG TABLET for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of DURATAF 25MG TABLET

Chronic hepatitis B

Medicinal Benefits Mweb

Key Benefits

DURATAF 25MG TABLET ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of DURATAF 25MG TABLET

  • Diarrhoea
  • Vomiting
  • Feeling sick (nausea)
  • Dizziness
  • Stomach pain
  • Joint pain
  • Feeling bloated
  • Wind (flatulence)
  • Feeling tired

Drug Warnings

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using DURATAF 25MG TABLET as DURATAF 25MG TABLET may cause dizziness, affecting your ability to drive or use machines. DURATAF 25MG TABLET is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Durataf 25 Tablet:
Coadministration of Cidofovir and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Durataf 25 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet may cause kidney problems, and combining it with Cyclophosphamide may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Durataf 25 Tablet if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
How does the drug interact with Durataf 25 Tablet:
Combining Colistin with Durataf 25 Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Colistin and Durataf 25 Tablet, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
How does the drug interact with Durataf 25 Tablet:
Co-administration of Meloxicam with Durataf 25 Tablet together can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Meloxicam with Durataf 25 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - feeling sick, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Durataf 25 Tablet:
Combine use of Durataf 25 Tablet with methotrexate may increase the levels or side effects of Durataf 25 Tablet.

How to manage the interaction:
Although there is a possible interaction between Durataf 25 Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Durataf 25 Tablet:
Coadministration of Vancomycin with Durataf 25 Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Durataf 25 Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Durataf 25 Tablet:
Coadministration of Naproxen and Durataf 25 Tablet may increase the effectiveness of Durataf 25 Tablet.

How to manage the interaction:
There may be a possible interaction between Naproxen and Durataf 25 Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Durataf 25 Tablet:
The combined use of Sulfasalazine and Durataf 25 Tablet can increase the risk or severity of of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and Durataf 25 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Durataf 25 Tablet:
Combining Durataf 25 Tablet with Modafinil may significantly reduce the blood levels of Durataf 25 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Durataf 25 Tablet and Modafinil, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Durataf 25 Tablet:
Taking Durataf 25 Tablet with tobramycin can increase the risk of kidney problems.

How to manage the interaction:
Although taking Durataf 25 Tablet and Tobramycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TOBRAMYCIN
  • PENTAMIDINE
  • VANCOMYCIN
  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • ADEFOVIR
  • IBUPROFEN

Habit Forming

No

Special Advise

  • If you take DURATAF 25MG TABLET , your doctor may regularly monitor liver function, kidney function, and bone density.

Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

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