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  3. Duraton Syrup

Prescription drug
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Therapeutic Class

COUGH AND COLD PREPARATIONS

Country of origin

India
Other Info - DU99780

Author Details

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FAQs

Duraton Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Consult your doctor before taking Duraton Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Duraton Syrup 72 hours prior to the surgery.

It is not recommended to take Duraton Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Duraton Syrup should be taken at least 14 days after the last dose of anti-depressants.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the scheduled dose. Do not take extra medicine to make up for the missed dose.

Duraton Syrup may rarely worsen the symptoms of glaucoma. Therefore, Duraton Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.

Disclaimer

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Alcohol

Caution

Avoid consumption of alcohol with Duraton Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Duraton Syrup.

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Pregnancy

Caution

The safety of Duraton Syrup in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Duraton Syrup is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if Duraton Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Duraton Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Duraton Syrup.

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Liver

Caution

Take Duraton Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Duraton Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Duraton Syrup is not recommended for children below 12 years of age. However, please consult a doctor if you have any concerns.

About Duraton Syrup

Duraton Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum.

Duraton Syrup contains Chlorpheniramine maleate, Phenylephrine and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Duraton Syrup helps provide relief from dry cough.

Your doctor will recommend the dose and duration of Duraton Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. Most of these side effects of Duraton Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or breastfeeding. Duraton Syrup is not recommended for children below 12 years of age. If you are about to undergo medical tests or surgery, please inform your doctor that you are taking Duraton Syrup. Duraton Syrup may cause dizziness, so drive or operate machinery only if you are alert. Avoid alcohol consumption as it may cause increased dizziness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Duraton Syrup

Dry cough

Medicinal Benefits Mweb

Medicinal Benefits

Duraton Syrup is a combination medicine belonging to a class of drugs called 'cough and cold preparations' primarily used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine is a decongestant that helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Duraton Syrup helps relieve cough, cold and allergic symptoms.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of Duraton Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

If you are allergic to Duraton Syrup or any other medicines, please tell your doctor. Consult your doctor if you are pregnant or breastfeeding. Duraton Syrup is not recommended for children below 12 years of age. Avoid taking Duraton Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor if you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Duraton Syrup:
Co-administration of Duraton Syrup and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Duraton Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Duraton Syrup:
Taking Tranylcypromine with Duraton Syrup can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Duraton Syrup with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Duraton Syrup:
Co-administration of Phenelzine and Duraton Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Duraton Syrup can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Duraton Syrup:
Co-administration of Isocarboxazid with Duraton Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Duraton Syrup and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Duraton Syrup:
Co-administration of Pargyline and Duraton Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Duraton Syrup and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Duraton Syrup:
Co-administration of Duraton Syrup and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Duraton Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Duraton Syrup:
Taking Rasagiline with Duraton Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duraton Syrup with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duraton Syrup:
Taking Duraton Syrup with Propofol may lead to increased levels of Duraton Syrup leading to side effects like high blood pressure.

How to manage the interaction:
Taking Duraton Syrup with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Duraton Syrup:
Taking Furazolidone with Duraton Syrup can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Duraton Syrup is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Duraton Syrup only after 14 days of stopping Furazolidone.
How does the drug interact with Duraton Syrup:
Co-administration of Duraton Syrup with Sevoflurane can increase the levels of Duraton Syrup and lead to side effects.

How to manage the interaction:
Taking Duraton Syrup with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ASPIRIN
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE

Habit Forming

No

Special Advise

  • Talk to your doctor if your symptoms do not improve even after taking Duraton Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash or headache after taking Duraton Syrup. 
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Duraton Syrup.

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

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