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  3. EMGRAF 1MG CAPSULE

Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

TACROLIMUS-1MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - EMG0010

Author Details

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FAQs

EMGRAF 1MG CAPSULE contains Tacrolimus, an immunosuppressant that works by the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

EMGRAF 1MG CAPSULE may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as sore throat or fever.

EMGRAF 1MG CAPSULE may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking EMGRAF 1MG CAPSULE because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using EMGRAF 1MG CAPSULE with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining EMGRAF 1MG CAPSULE with other medications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption with EMGRAF 1MG CAPSULE as it may increase the risk of adverse effects. Please consult a doctor before consuming alcohol with EMGRAF 1MG CAPSULE.

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Pregnancy

Caution

Using Tacrolimus during pregnancy may cause kidney dysfunction or neonatal hyperkalemia (high potassium levels in the blood). Therefore, please consult a doctor if you are pregnant before taking EMGRAF 1MG CAPSULE and if you are a woman of childbearing age, use effective contraceptive methods while using EMGRAF 1MG CAPSULE.

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Breast Feeding

Consult your doctor

EMGRAF 1MG CAPSULE may be excreted in breast milk. Therefore, please inform your doctor if you are a breastfeeding mother before taking EMGRAF 1MG CAPSULE. You should avoid taking EMGRAF 1MG CAPSULE during breastfeeding or avoid breastfeeding while on treatment with EMGRAF 1MG CAPSULE.

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Driving

Caution

EMGRAF 1MG CAPSULE may cause vision problems or nervous disturbances in a few people. Therefore, avoid driving if you experience any of these symptoms after taking EMGRAF 1MG CAPSULE.

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Liver

Consult your doctor

Please consult a doctor if you have liver diseases/conditions before taking EMGRAF 1MG CAPSULE.

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Kidney

Consult your doctor

Please consult a doctor if you have Kidney diseases/conditions before taking EMGRAF 1MG CAPSULE.

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Children

Safe if prescribed

EMGRAF 1MG CAPSULE should be used in children in doses as advised by a doctor only.

About EMGRAF 1MG CAPSULE

EMGRAF 1MG CAPSULE belongs to a class of drugs called immunosuppressants used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

EMGRAF 1MG CAPSULE contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thus, prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Take EMGRAF 1MG CAPSULE as prescribed. You are advised to use EMGRAF 1MG CAPSULE for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of EMGRAF 1MG CAPSULE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using EMGRAF 1MG CAPSULE. Avoid alcohol consumption with EMGRAF 1MG CAPSULE. Drive only if you are alert, as EMGRAF 1MG CAPSULE may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking EMGRAF 1MG CAPSULE. EMGRAF 1MG CAPSULE may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of EMGRAF 1MG CAPSULE

Prevent transplanted organ rejection

Medicinal Benefits Mweb

Medicinal Benefits

EMGRAF 1MG CAPSULE contains Tacrolimus, an immunosuppressant used to prevent organ rejection after a transplant. EMGRAF 1MG CAPSULE suppresses the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Directions for Use

Capsule: Take the capsule as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Granules: The granules should be mixed with water to make an oral suspension. Drink the prepared suspension immediately. Do not save the suspension for later use.

Side Effects of EMGRAF 1MG CAPSULE

  • Nausea
  • Diarrhoea
  • Headache
  • Kidney problems
  • Infection
  • Constipation
  • Fever
  • High blood pressure

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using EMGRAF 1MG CAPSULE. Avoid alcohol consumption with EMGRAF 1MG CAPSULE. Drive only if you are alert, as EMGRAF 1MG CAPSULE may cause vision problems or nervous disturbances in some people. If you are about to get vaccinated, inform your doctor before taking EMGRAF 1MG CAPSULE. EMGRAF 1MG CAPSULE may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking EMGRAF 1MG CAPSULE, you are advised to wear protective clothing and sunscreen while going out. You are recommended to use glass or metal materials to prepare the oral suspension. Avoid using plastic (PVC) materials to prepare the suspension as the granules will stick to a plastic container, and your child may not receive their full dose. Do not inhale or let the granules or prepared oral suspension come in contact with your skin or eyes. In case of accidental contact with skin, wash the area well with soap and water, and if it comes in contact with the eyes, rinse with plain water.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule with Mifepristone may significantly increase the blood levels of Emgraf 1mg Capsule, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Emgraf 1mg Capsule:
Combining Emgraf 1mg Capsule with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking cidofovir with Emgraf 1mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Emgraf 1mg Capsule with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule together with clozapine can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Emgraf 1mg Capsule and clozapine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule together with moxifloxacin can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Emgraf 1mg Capsule and moxifloxacin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Fluconazole may increase the blood levels of Emgraf 1mg Capsule and may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction, fluconazole can be taken with Emgraf 1mg Capsule if prescribed by the doctor. However, consult the doctor if you experience signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Emgraf 1mg Capsule:
Taking Emgraf 1mg Capsule with balsalazide can increase risk of kidney problems.

How to manage the interaction:
Although taking Emgraf 1mg Capsule and balsalazide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TACROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Emgraf 1mg Capsule treatment may lead to increased Emgraf 1mg Capsule levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Emgraf 1mg Capsule.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • SIROLIMUS
  • NELFINAVIR
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TRIAMTERENE
  • AMILORIDE

Habit Forming

No

Special Advise

Regular blood tests and certain other tests are recommended while taking EMGRAF 1MG CAPSULE to check blood sugar levels, kidney functioning and potassium levels in the blood.

Diet & Lifestyle Advise

Kidney transplant:

  • Include fruits and vegetables in your daily routine.
  • Follow a vitamin-C-rich diet.
  • Reduce salt intake.
  • Eat a handful of walnuts and almonds every day.
  • Reduce intake of unhealthy cholesterol and fats.
  • Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

  • Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
  • Maintain a low-fat and low-salt diet.
  • Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
  • Stay hydrated by drinking sufficient water and other fluids.
  • Avoid alcohol consumption.
  • Avoid grapefruit and grapefruit juice. 

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