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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- HYPERTENSIVES

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - END0447

Author Details

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FAQs

Endoblock T Kit Combipack contains Ambrisentan and tadalafil. Tadalafil aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.

Yes, Endoblock T Kit Combipack can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.

Even if you feel better, do not stop using Endoblock T Kit Combipack. It should be used exactly as prescribed by your doctor to minimise the recurrence of symptoms and worsening of the disease.

No, it is a medication recommended by a doctor to treat or prevent specific medical issues. Taking it on your own can result in unfavourable side effects.

Endoblock T Kit Combipack is safe if taken in the dose and for the term prescribed by your doctor. Take it exactly as directed and do not miss any doses. Follow your doctor's instructions carefully and notify the doctor if any of the adverse effects bother you.

Endoblock T Kit Combipack should be used with caution if you have any allergic reactions, heart failure, liver or renal disease, lung problems (pulmonary fibrosis), anaemia, oedema (fluid retention), or hypotension (low blood pressure).

It is recommended not to take Endoblock T Kit Combipack along with mediations used to relieve chest pain (nitrates). Please consult your doctor if you have concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is advised to limit or quit the consumption of alcohol as it may increase the risk of low blood pressure.

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Pregnancy

Unsafe

Endoblock T Kit Combipack is not recommended in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Endoblock T Kit Combipack in breastfeeding/nursing mothers. Endoblock T Kit Combipack should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Caution

Endoblock T Kit Combipack causes drowsiness and dizziness, so drive only if you are alert.

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Liver

Caution

Endoblock T Kit Combipack may increase liver enzymes. Before taking Endoblock T Kit Combipack, inform your doctor if you have/had liver illness.

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Kidney

Caution

In cases of renal impairment, take Endoblock T Kit Combipack with caution. If you have kidney problems, you should consult a doctor before beginning Endoblock T Kit Combipack. Your doctor will prescribe if the benefits outweigh the risks.

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Children

Unsafe

Safety and effectiveness of Endoblock T Kit Combipack have not been established in patients below 18 years of age.

About Endoblock T Kit Combipack

Endoblock T Kit Combipack belongs to the class of medicines called antihypertensives, primarily used to treat pulmonary arterial hypertension (high blood pressure affecting arteries in the lungs). Pulmonary hypertension is defined as high blood pressure in the blood veins that supply the blood to the lungs (pulmonary arteries). It can affect the arteries of the lungs and the right side of the heart. The common symptoms of pulmonary hypertension are shortness of breath, dizziness, palpitations, and chest pressure.

Endoblock T Kit Combipack is a combination of two medications: ambrisentan and tadalafil. Tadalafil belongs to a class of drugs known as phosphodiesterase-5 (PDE5) inhibitors. It aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan belongs to a class of drugs known as 'endothelin receptor antagonists.' Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.

Endoblock T Kit Combipack can be taken with or without food. Swallow the tablet whole with a glass of water; do not crush, chew or break it. You are advised to take Endoblock T Kit Combipack for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Endoblock T Kit Combipack can cause side effects like headache, flushing, blocked nose, palpitations, diarrhoea, nausea, indigestion, muscle aches and pain. These side effects are unfamiliar to everyone and vary from person to person. Please get in touch with your doctor if you experience any of the side effects persistently.

If you are allergic to any of the ingredients of Endoblock T Kit Combipack, please do not take it. Stopping Endoblock T Kit Combipack without consulting your doctor may aggravate your condition and increase your chances of future cardiac problems. Consult your doctor if you are pregnant or breastfeeding. Endoblock T Kit Combipack causes drowsiness and dizziness, so drive only if you are alert. Endoblock T Kit Combipack should not be given to children as safety and effectiveness have not been established. Alcohol should not be consumed with Endoblock T Kit Combipack since it may raise the risk of low blood pressure. Keep your doctor up to date on your medical condition and medications to rule out any potential side effects.

Uses of Endoblock T Kit Combipack

Pulmonary arterial hypertension (PAH)

Medicinal Benefits Mweb

Medicinal Benefits

Endoblock T Kit Combipack is an antihypertensive drug used to treat pulmonary arterial hypertension (PAH). Endoblock T Kit Combipack contains tadalafil (PDE-5 inhibitor) and ambrisentan (endothelin receptor antagonist). Tadalafil aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.

Directions for Use

Endoblock T Kit Combipack should be swallowed as a whole with a glass of water with or without food or taken as directed by the physician. Do not crush or chew the tablet.

Side Effects of Endoblock T Kit Combipack

  • Headache
  • Flushing (redness of the skin)
  • Nasal and sinus congestion (blocked nose)
  • Nausea
  • Indigestion
  • Muscle aches
  • Back pain
  • Pain in the extremity
  • Dizziness

Drug Warnings

If you are allergic to any of the ingredients of Endoblock T Kit Combipack, please do not take it. Stopping Endoblock T Kit Combipack without consulting your doctor may aggravate your condition and increase your chances of future cardiac problems. Endoblock T Kit Combipack is not recommended during pregnancy because it is harmful to the foetus. Before using Endoblock T Kit Combipack, you should definitely get a negative pregnancy test. Also, if you are undergoing treatment with Endoblock T Kit Combipack, please use reliable forms of birth control to avoid pregnancy. Brief your medical history to the doctor if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure). Endoblock T Kit Combipack causes drowsiness and dizziness, so drive if you are alert. Avoid consuming alcohol with Endoblock T Kit Combipack as it may raise the chance of developing low blood pressure. Endoblock T Kit Combipack is not suggested for patients under the age of 18.

Drug-Drug Interactions

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TadalafilAmyl nitrite
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • ILOPROST
  • EPOPROSTENOL
  • ORGANIC NITRATE
  • TAMSULOSIN
  • AMLODIPINE
  • ENALAPRIL
  • METOPROLOL
  • ITRACONAZOLE
  • RIFAMPICIN
  • CYCLOSPORINE

Habit Forming

No

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Your doctor may suggest liver function tests since Endoblock T Kit Combipack may cause a change in liver enzymes.

Diet & Lifestyle Advise

  • Keep your heart healthy by exercising on a regular basis.
  • Consume natural and nutritious foods while avoiding high-sodium processed foods.
  • Reduce your salt intake in your diet to keep your blood pressure stable.
  • Obesity is a risk factor for hypertension, so reduce those excess pounds.
  • Avoid smoking and drinking alcohol.
  • High blood pressure can also be caused by chronic stress. As a result, avoid stress and make time for yourself to relax and engage in things that you enjoy.
  • Include heart-healthy omega 3 fatty acid-containing foods and beverages in your daily diet.
  • To lower your blood pressure (BP), you can also use low-fat cooking oils such as olive oil, coconut oil, soybean oil and canola oil.

Endoblock T Kit Combipack Substitute

Substitutes safety advice

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Recommended for a 30-day course: 2 Packets

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