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  3. Entospas 10mg/250mg Tablet

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Biophar Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTISPASMODICS

Country of origin

India
Other Info - EN44298

Author Details

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FAQs

Entospas 10mg/250mg Tablet contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of Entospas 10mg/250mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Entospas 10mg/250mg Tablet is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.

Dry mouth could be a side-effect of Entospas 10mg/250mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Entospas 10mg/250mg Tablet should not be taken for more than 7days. Do not take Entospas 10mg/250mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.

Entospas 10mg/250mg Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Entospas 10mg/250mg Tablet only as prescribed, and do not overdose.

Disclaimer

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Entospas 10mg/250mg Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended to breastfeed while taking Entospas 10mg/250mg Tablet. Consult your doctor before taking Entospas 10mg/250mg Tablet if you are breastfeeding.

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Driving

Caution

Entospas 10mg/250mg Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Unsafe

Entospas 10mg/250mg Tablet should not be used in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Entospas 10mg/250mg Tablet is not recommended for children as safety and effectiveness were not established.

About Entospas 10mg/250mg Tablet

Entospas 10mg/250mg Tablet is a combination medicine used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. Colic is a form of pain that starts and stops abruptly.

Entospas 10mg/250mg Tablet is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Entospas 10mg/250mg Tablet helps in relieving pain.

You are advised to take Entospas 10mg/250mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Entospas 10mg/250mg Tablet may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Entospas 10mg/250mg Tablet may cause dizziness and drowsiness, so drive with caution. Entospas 10mg/250mg Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Entospas 10mg/250mg Tablet as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Entospas 10mg/250mg Tablet

Abdominal pain, dysmenorrhea (period pain), colicky pain

Medicinal Benefits Mweb

Medicinal Benefits

Entospas 10mg/250mg Tablet is a combination of two drugs, namely: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Entospas 10mg/250mg Tablet is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, Entospas 10mg/250mg Tablet helps in relieving pain.

Directions for Use

Take Entospas 10mg/250mg Tablet with food to prevent stomach upset. Swallow Entospas 10mg/250mg Tablet as a whole with a glass of water, do not chew or break it.

Side Effects of Entospas 10mg/250mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache
  • Dry mouth
  • Weakness
  • Nervousness
  • Loss of appetite

Drug Warnings

Do not take Entospas 10mg/250mg Tablet if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Entospas 10mg/250mg Tablet may cause dizziness and drowsiness, so drive only if you are alert. Entospas 10mg/250mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol with Entospas 10mg/250mg Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Entospas 10mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Entospas 10mg/250mg Tablet unless prescribed. 

Drug-Drug Interactions

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DicyclominePramlintide
Critical
DicyclominePotassium citrate
Critical

Drug-Drug Interactions

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DicyclominePramlintide
Critical
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Pramlintide with Entospas 10mg/250mg Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Entospas 10mg/250mg Tablet:
Taking Entospas 10mg/250mg Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Entospas 10mg/250mg Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
Coadministration of Entospas 10mg/250mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Entospas 10mg/250mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Entospas 10mg/250mg Tablet with Zonisamide may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Entospas 10mg/250mg Tablet and Zonisamide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Entospas 10mg/250mg Tablet with Topiramate may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Entospas 10mg/250mg Tablet and Topiramate together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue the medication without consulting a doctor.
DicyclomineSecretin
Severe
How does the drug interact with Entospas 10mg/250mg Tablet:
Co-administration of Secretin human with Entospas 10mg/250mg Tablet may decrease the therapeutic efficacy of Secretin human.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet with Secretin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
The combined use of Entospas 10mg/250mg Tablet and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Entospas 10mg/250mg Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Entospas 10mg/250mg Tablet:
Using Entospas 10mg/250mg Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Entospas 10mg/250mg Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • FUROSEMIDE
  • LITHIUM
  • QUINIDINE
  • PHENOTHIAZINE
  • METHOTREXATE
  • WARFARIN
  • CLOPIDOGREL
  • DIGOXIN
  • GLIMEPIRIDE
  • GLICLAZIDE
  • GLIBENCLAMIDE
  • GENTAMICIN
  • TOBRAMYCIN
  • AMIKACIN
  • CYCLOSPORINE
  • MIFEPRESTONE
  • TACROLIMUS
  • ZIDOVUDINE
  • METOCLOPRAMIDE

Habit Forming

No

Special Advise

  • Entospas 10mg/250mg Tablet may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking Entospas 10mg/250mg Tablet.
  • Entospas 10mg/250mg Tablet may cause a false-positive reaction for urinary bile test. Inform the person doing the test that you are taking Entospas 10mg/250mg Tablet.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

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