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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ENZ0218

FAQs

Yes, in most of the patients it is safe to take Enzoflam-SP Tablet but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.

Enzoflam-SP Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,

A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.

Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.

No. Enzoflam-SP Tablet is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.

Taking excessive alcohol with Enzoflam-SP Tablet can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Enzoflam-SP Tablet .

Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Enzoflam-SP Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Enzoflam-SP Tablet to be taken with caution, specially if you are pregnant. Your doctor may adjust your dose depending upon your conditions, if he/she feels the benefits over weigh the risks.

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Breast Feeding

Caution

Only consume Enzoflam-SP Tablet if it has been prescribed by a doctor as the safety data in nursing mothers is lacking. Inform your doctor if you are breastfeeding.

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Driving

Caution

Enzoflam-SP Tablet may affect driving as it causes dizziness.

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Liver

Caution

Enzoflam-SP Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Enzoflam-SP Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Enzoflam-SP Tablet should not be given to children without prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and severity of condition.

About Enzoflam-SP Tablet

Enzoflam-SP Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Enzoflam-SP Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take Enzoflam-SP Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of Enzoflam-SP Tablet do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Enzoflam-SP Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Enzoflam-SP Tablet

 Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Medicinal Benefits Mweb

Medicinal Benefits

Enzoflam-SP Tablet consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Enzoflam-SP Tablet

  • Nausea

  • Stomach Pain

  • Loss of appetite

  • Diarrhoea

  • Stomach upset

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Enzoflam-SP Tablet as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Enzoflam-SP Tablet on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Enzoflam-SP Tablet . Use with caution in pregnancy and breastfeeding. Do not self-administer Enzoflam-SP Tablet if you are pregnant or are nursing.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacBromfenac
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Enzoflam-SP Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacBromfenac
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Enzoflam-SP Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacApixaban
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Enzoflam-SP Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacAcalabrutinib
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking acalabrutinib together with Enzoflam-SP Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Dasatinib together with Enzoflam-SP Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacAmiloride
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking amiloride with Enzoflam-SP Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Enzoflam-SP Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacIndometacin
Severe
How does the drug interact with Enzoflam-SP Tablet:
The combined use of Enzoflam-SP Tablet and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacNaproxen
Severe
How does the drug interact with Enzoflam-SP Tablet:
Coadministration of Enzoflam-SP Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Enzoflam-SP Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • WARFARIN

Habit Forming

No

Special Advise

  • Paracetamol is a component of Enzoflam-SP Tablet which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
  • Although Enzoflam-SP Tablet provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Enzoflam-SP Tablet Substitute

Substitutes safety advice
  • Aceelo PS Tablet 10's

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    8.80per tablet
  • Zerodol-SP Tablet 10's

    by Others

    12.51per tablet
  • Signoflam Tablet 10's

    by Others

    14.22per tablet
  • Hifenac-SP Tablet 10's

    by Others

    12.02per tablet
  • Hifenac-D Tablet 10's

    by Others

    12.02per tablet

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