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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Composition :

EPLERENONE-50MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

DIURETIC

Country of origin

INDIA

Manufacturer/Marketer address

MSN Laboratories Pvt.Ltd., MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA
Other Info - EPL0009

FAQs

Eplehef 50 Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

It is not common, but Eplehef 50 Tablet can sometimes increase the blood sugar level. Therefore, monitoring your blood sugar level to check for any fluctuations is crucial. Also, the use of Eplehef 50 Tablet should be avoided in patients with type 2 diabetes and some kidney problems.

Yes, Eplehef 50 Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Eplehef 50 Tablet . Please monitor your electrolyte level regularly to avoid increased blood potassium levels.

It is a medical term for fluid retention or overload. Due to edema, the legs, hands, and other body parts start swelling, increasing blood pressure. If it does not subside, please consult your doctor immediately.

The main side effect of Eplehef 50 Tablet is peeing (urination) more often than normal. Most people need to pee about 30 minutes after taking Eplehef 50 Tablet and again within a few hours. Do not take Eplehef 50 Tablet before going to bed, or you may have to wake up at night to go for urination frequently.

No, it is not recommended to take Eplehef 50 Tablet along with lithium. It might increase lithium's level in the blood and lead to unpleasant side effects like visual impairment, loss of appetite, and muscle weakness. So, inform your doctor before starting Eplehef 50 Tablet if you take lithium is recommended.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Eplehef 50 Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Eplehef 50 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Breast-feeding must be avoided during treatment with Eplehef 50 Tablet . It is only if prescribed by a doctor and if benefits overweigh harms.

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Driving

Unsafe

It is not recommended to drive after taking Eplehef 50 Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

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Liver

Caution

Inform your doctor before receiving the Eplehef 50 Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Kidney

Caution

Inform your doctor before receiving the Eplehef 50 Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Caution

Eplehef 50 Tablet is not recommended for children below 12 years of age.

About Eplehef 50 Tablet

Eplehef 50 Tablet belongs to a class of medicine called 'diuretics' (water pills) primarily used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to oedema (fluid retention). Blood pressure measures the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

Eplehef 50 Tablet contains Eplerenone, which is prescribed for the treatment of hypertension. Eplehef 50 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Take Eplehef 50 Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Eplehef 50 Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Eplehef 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Eplehef 50 Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you have any kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Eplehef 50 Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Eplehef 50 Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Please take Eplehef 50 Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Eplehef 50 Tablet along with lithium to prevent serious side effects.

Uses of Eplehef 50 Tablet

Hypertension (high blood pressure), Edema

Medicinal Benefits Mweb

Medicinal Benefits

Eplehef 50 Tablet  primarily used to treat hypertension (high blood pressure) and heart failure. It also treats edema (reduces swelling) caused due to other conditions. Eplehef 50 Tablet works by increasing the amount of urine passing from the kidneys. It effectively reduces excess fluid levels in the body and reduces the heart's workload, and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Eplehef 50 Tablet

  • Dizziness
  • Nausea
  • Dizziness
  • Headache
  • Cough
  • Increased creatinine and potassium in the blood
  • Fatigue

Drug Warnings

Eplehef 50 Tablet should not be given to the people allergic to Eplehef 50 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2 and patients with nil urine output (anuria), pregnant women, planning to get pregnant and breastfeeding women. Eplehef 50 Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Eplehef 50 Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Eplehef 50 Tablet . Do not take extra potassium supplements or potassium-rich foods such as bananas and broccoli with Eplehef 50 Tablet . It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Eplehef 50 Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Eplehef 50 Tablet along with lithium to prevent serious side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Eplehef 50 Tablet:
Coadministration of Ketoconazole with Eplehef 50 Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Eplehef 50 Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Eplehef 50 Tablet:
Co-administration of Eplehef 50 Tablet and Clarithromycin may significantly increase the blood levels and effects of Eplehef 50 Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Eplehef 50 Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
EplerenonePotassium iodide
Critical
How does the drug interact with Eplehef 50 Tablet:
Combining Eplehef 50 Tablet with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Eplehef 50 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplehef 50 Tablet:
Combining Eplehef 50 Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Eplehef 50 Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplehef 50 Tablet:
Using Eplehef 50 Tablet together with Potassium chloride may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking potassium chloride with Eplehef 50 Tablet is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplehef 50 Tablet:
Coadministration of posaconazole with Eplehef 50 Tablet can increase the blood levels of Eplehef 50 Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Eplehef 50 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EplerenoneSaquinavir
Critical
How does the drug interact with Eplehef 50 Tablet:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Eplehef 50 Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Eplehef 50 Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenoneNefazodone
Critical
How does the drug interact with Eplehef 50 Tablet:
Coadministration of Nefazodone with Eplehef 50 Tablet can increase the levels of Eplehef 50 Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Eplehef 50 Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Eplehef 50 Tablet:
Taking Eplehef 50 Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Eplehef 50 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplehef 50 Tablet:
The blood levels and effects of Eplehef 50 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Eplehef 50 Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ASPIRIN
  • WARFARIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • NELFINAVIR
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • LITHIUM

Habit Forming

No

Special Advise

  • Treatment with Eplehef 50 Tablet requires regular monitoring of serum potassium and creatinine level.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Monitor your blood sugar level daily and if there is too much fluctuation, then immediately contact your doctor.

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are highly antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Elevate your legs or the swollen area on a chair or pillow.
  • Avoid standing or sitting for extended periods.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

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