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  1. Home
  2. Medicine

  3. Epo 150 Tablet SR

Prescription drug
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Epo 150 Tablet SR, Pack of 1 Tablet
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Extra 15% Off with Bank Offers

Composition :

EPALRESTAT-150MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIDIABETICS

Country of origin

India
Other Info - EP75028

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Epo 150 Tablet SR works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epo 150 Tablet SR prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of Epo 150 Tablet SR. Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

Epo 150 Tablet SR might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epo 150 Tablet SR. Regularly monitor blood pressure levels while taking Epo 150 Tablet SR.

Do not discontinue Epo 150 Tablet SR without consulting your doctor. To treat your condition effectually, continue taking Epo 150 Tablet SR for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epo 150 Tablet SR.

Epo 150 Tablet SR may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Epo 150 Tablet SR as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the use of Epo 150 Tablet SR in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the use of Epo 150 Tablet SR in breastfeeding women. Consult your doctor before taking Epo 150 Tablet SR; your doctor will decide whether Epo 150 Tablet SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Epo 150 Tablet SR may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Epo 150 Tablet SR should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Epo 150 Tablet SR should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epo 150 Tablet SR should not be given to children as safety and efficacy have not been established.

Product Substitutes

Reference

  1. https://www.mims.com/malaysia/drug/info/epalrestat?mtype=generic
  2. https://www.medindia.net/doctors/drug_information/epalrestat.htm

About Epo 150 Tablet SR

Epo 150 Tablet SR belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Epo 150 Tablet SR contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epo 150 Tablet SR prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

You are advised to take Epo 150 Tablet SR for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Epo 150 Tablet SR if you are pregnant or breastfeeding. Epo 150 Tablet SR may cause drowsiness and dizziness, so drive only if you are alert. Epo 150 Tablet SR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epo 150 Tablet SR as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Epo 150 Tablet SR

Diabetic neuropathy (diabetic nerve pain)

Medicinal Benefits Mweb

Medicinal Benefits

Epo 150 Tablet SR belongs to a group of medicines called aldose reductase inhibitors. Epo 150 Tablet SR is used for the management of diabetic neuropathy. Epo 150 Tablet SR works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epo 150 Tablet SR prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

Directions for Use

Swallow Epo 150 Tablet SR as a whole with a glass of water; do not chew, or break it.

Side Effects of Epo 150 Tablet SR

  • Dizziness
  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea

Drug Warnings

Do not take Epo 150 Tablet SR if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epo 150 Tablet SR if you are pregnant or breastfeeding. Epo 150 Tablet SR may cause drowsiness and dizziness, so drive only if you are alert. Epo 150 Tablet SR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epo 150 Tablet SR as it could lead to increased drowsiness and sleepiness.

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Epo 150 Tablet SR Substitute

Substitutes safety advice

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