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Epstat-50 Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epstat-50 Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.
Diarrhoea could be a side-effect of Epstat-50 Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.
Epstat-50 Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epstat-50 Tablet . Regularly monitor blood pressure levels while taking Epstat-50 Tablet .
Do not discontinue Epstat-50 Tablet without consulting your doctor. To treat your condition effectually, continue taking Epstat-50 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epstat-50 Tablet .
Epstat-50 Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
Alcohol
Unsafe
Avoid consumption of alcohol while taking Epstat-50 Tablet as it may cause increased dizziness.
Pregnancy
Caution
Limited information is available regarding the use of Epstat-50 Tablet in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Limited information is available regarding the use of Epstat-50 Tablet in breastfeeding women. Consult your doctor before taking Epstat-50 Tablet ; your doctor will decide whether Epstat-50 Tablet can be taken by breastfeeding mothers or not.
Driving
Caution
Epstat-50 Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.
Liver
Caution
Epstat-50 Tablet should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Epstat-50 Tablet should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Epstat-50 Tablet should not be given to children as safety and efficacy have not been established.
Product Substitutes
About Epstat-50 Tablet
Epstat-50 Tablet belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.
Epstat-50 Tablet contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epstat-50 Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.
You are advised to take Epstat-50 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor before taking Epstat-50 Tablet if you are pregnant or breastfeeding. Epstat-50 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epstat-50 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epstat-50 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Epstat-50 Tablet
Medicinal Benefits
Epstat-50 Tablet belongs to a group of medicines called aldose reductase inhibitors. Epstat-50 Tablet is used for the management of diabetic neuropathy. Epstat-50 Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epstat-50 Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).
Directions for Use
Side Effects of Epstat-50 Tablet
Drug Warnings
Do not take Epstat-50 Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epstat-50 Tablet if you are pregnant or breastfeeding. Epstat-50 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epstat-50 Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epstat-50 Tablet as it could lead to increased drowsiness and sleepiness.
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