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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

METOCLOPRAMIDE-5MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIEMETICS

Country of origin

India
Other Info - ES24138

FAQs

Esmet 5mg Injection works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Esmet 5mg Injection may cause tardive dyskinesia (movement disorder) that is often irreversible. The risk increases with the duration of treatment and dosage. Esmet 5mg Injection therapy should be discontinued in patients who develop the symptoms of tardive dyskinesia. Consult your doctor immediately if you notice symptoms such as involuntary movements of the face, tongue, mouth, jaw, trunk and/or extremities.

Esmet 5mg Injection may be used to facilitate small bowel intubation (the process of passing a small, flexible plastic tube through the nose/mouth into the stomach/small intestine) in adults and pediatric patients in whom the tube does not pass the pylorus (the opening from the stomach into the duodenum) with conventional manoeuvres.

Treatment with Esmet 5mg Injection should be avoided for longer than 12 weeks except in rare cases where benefits outweigh the risks of developing tardive dyskinesia.

Esmet 5mg Injection may cause depression in people with or without a medical history of depression. Consult your doctor immediately if you have any suicidal thoughts, such as killing or harming yourself.

Esmet 5mg Injection may be used to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Esmet 5mg Injection as it may cause increased sleepiness and drowsiness.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Esmet 5mg Injection may be excreted in human milk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Esmet 5mg Injection may cause dizziness and drowsiness. Do not drive or operate machinery until you know how Esmet 5mg Injection affects you.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Esmet 5mg Injection is not recommended for children below one year.

About Esmet 5mg Injection

Esmet 5mg Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Esmet 5mg Injection is also used to treat delayed gastric emptying. Esmet 5mg Injection may be used to facilitate small bowel intubation and to stimulate gastric emptying and intestinal transit of barium.

Esmet 5mg Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Esmet 5mg Injection may cause common side-effects such as drowsiness, fatigue, dizziness, headache, and bowel disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Esmet 5mg Injection may cause drowsiness and dizziness affecting your ability to drive and operate machinery. Esmet 5mg Injection is not recommended for children below one year. Avoid consuming alcohol while on treatment with Esmet 5mg Injection as it could lead to increased drowsiness. Treatment with Esmet 5mg Injection is not recommended for longer than 12 weeks, except in rare cases.

Uses of Esmet 5mg Injection

Nausea, vomiting, delayed gastric emptying

Medicinal Benefits Mweb

Medicinal Benefits

Esmet 5mg Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Esmet 5mg Injection is also used to treat delayed gastric emptying. Esmet 5mg Injection may be used to facilitate small bowel intubation and to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine. Esmet 5mg Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Directions for Use

Esmet 5mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Esmet 5mg Injection

  • Drowsiness
  • Fatigue
  • Dizziness
  • Headache
  • Bowel disturbances

Drug Warnings

Do not take Esmet 5mg Injection if you are allergic to any of its components; if you have gastrointestinal bleeding, mechanical obstruction/perforation, pheochromocytoma (tumour in the adrenal glands), or epilepsy. Esmet 5mg Injection may cause neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), extrapyramidal symptoms (shaking, tremor, stiffness and involuntary movement), Tardive dyskinesia (movement disorder), Parkinson-like symptoms (bradykinesia, tremor, cogwheel rigidity, or mask-like facies), and depression. Inform your doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, Parkinson’s disease, methaemoglobinaemia, or liver or kidney problems. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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MetoclopramideTrifluoperazine
Critical
MetoclopramideMaprotiline
Critical

Drug-Drug Interactions

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MetoclopramideTrifluoperazine
Critical
How does the drug interact with Esmet 5mg Injection:
Co-administration of Esmet 5mg Injection with Trifluoperazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Esmet 5mg Injection with Trifluoperazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping., contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideMaprotiline
Critical
How does the drug interact with Esmet 5mg Injection:
Co-administration of Esmet 5mg Injection with Maprotiline can increase the risk or severity of side effects.

How to manage the interaction:
Taking Maprotiline with Esmet 5mg Injection is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Consult your doctor if you see symptoms like dizziness, drowsiness, confusion, difficulty concentrating, or impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without consulting a doctor.
MetoclopramideQuetiapine
Critical
How does the drug interact with Esmet 5mg Injection:
Coadministration of Esmet 5mg Injection with quetiapine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Esmet 5mg Injection with Quetiapine is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideAmisulpride
Critical
How does the drug interact with Esmet 5mg Injection:
Taking Esmet 5mg Injection with Amisulpride may increase the risk or severity of side effects.

How to manage the interaction:
Taking Amisulpride with Esmet 5mg Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
MetoclopramideAmoxapine
Critical
How does the drug interact with Esmet 5mg Injection:
Co-administration of Esmet 5mg Injection with Amoxapine can increase the risk of side effects.

How to manage the interaction:
Taking Esmet 5mg Injection with Amoxapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideTetrabenazine
Critical
How does the drug interact with Esmet 5mg Injection:
Coadministration of Tetrabenazine and Esmet 5mg Injection can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Tetrabenazine and Esmet 5mg Injection together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideClozapine
Critical
How does the drug interact with Esmet 5mg Injection:
Co-administration of Esmet 5mg Injection with Clozapine can increase the risk of side effects.

How to manage the interaction:
Taking Esmet 5mg Injection with Clozapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideCitalopram
Critical
How does the drug interact with Esmet 5mg Injection:
Coadministration of Citalopram with Esmet 5mg Injection can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Citalopram with Esmet 5mg Injection is generally avoided as it can possibly result in an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramideAripiprazole
Critical
How does the drug interact with Esmet 5mg Injection:
Co-administration of Esmet 5mg Injection with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Esmet 5mg Injection is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideTrazodone
Critical
How does the drug interact with Esmet 5mg Injection:
Coadministration of Esmet 5mg Injection with Trazodone can rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Esmet 5mg Injection with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any symptoms like dizziness, fever, excessive sweating, shivering, blurred vision, muscle stiffness, stomach cramps, nausea, vomiting, or diarrhoea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LEVODOPA
  • DIGOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Esmet 5mg Injection Substitute

Always consult your doctor before taking any new medications and supplements

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