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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Bioceutics Inc

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esonap Tablet

Esonap Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers used to reduce and relieve pain. Pain is a highly unpleasant physical sensation caused by illness or injury.

Esonap Tablet combines Naproxen (painkiller) and esomeprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, combined with esomeprazole (proton pump inhibitors), it reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Take Esonap Tablet as prescribed by your doctor. You are advised to take Esonap Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea. Most of these side effects of Esonap Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking this medicine, inform your doctor if you have any known allergy to Naproxen, esomeprazole, other NSAIDs, or other medications. If pregnant or breastfeeding, please inform your doctor before taking the Esonap Tablet . Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use Esonap Tablet only when prescribed by a doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Esonap Tablet to rule out any side effects.

Uses of Esonap Tablet

Pain relief.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Esonap Tablet contains Naproxen and esomeprazole (antacid). Naproxen is an anti-inflammatory (reduces inflammation) and an analgesic (relieves pain) agent that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. It also treats fibrositis (muscle pain and stiffness), tenosynovitis (swelling of tendons), low back pain, strains, and sprains. NSAIDs such as Naproxen have been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. To reduce gastric discomfort and stomach ulceration risk, it is combined with esomeprazole (a proton pump inhibitor that inhibits gastric acid secretion) to reduce stomach acid production during long-term treatment for people with pre-existing stomach ulcers or for people having a history of developing stomach ulcers while using NSAIDs. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Esonap Tablet if you are allergic to Esonap Tablet . Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin), such as naproxen, may increase the risk of heart attack, stroke, and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, are older, are alcoholics, or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems, so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Esonap Tablet is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Esonap Tablet . Esonap Tablet should not be given to children unless prescribed by a doctor. Do not take any other NSAIDs for pain relief along with Esonap Tablet unless prescribed. Prolonged proton pump inhibitors like esomeprazole may cause brittle bones, so your doctor may recommend taking Vitamin D and calcium while using Esonap Tablet . Do not consume alcohol with Esonap Tablet as it may increase the risk of stomach bleeding or ulcer.

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esonap Tablet:
Esonap Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esonap Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Esonap Tablet:
Taking cidofovir with Esonap Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Esonap Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
How does the drug interact with Esonap Tablet:
Co-administration of Esonap Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Esonap Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
How does the drug interact with Esonap Tablet:
Coadministration of Ketorolac with Esonap Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Esonap Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Esonap Tablet:
Combining Esonap Tablet with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Esonap Tablet with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Esonap Tablet:
Taking tacrolimus with Esonap Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Esonap Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esonap Tablet:
Coadministration of Clopidogrel with Esonap Tablet may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Esonap Tablet together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Esonap Tablet:
Esonap Tablet decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esonap Tablet and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
How does the drug interact with Esonap Tablet:
Using Dasatinib together with Esonap Tablet may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Esonap Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esonap Tablet:
Coadministration of erlotinib and Esonap Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Esonap Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Foods containing flavonoids, such as soy, berries, broccoli, grapes and green tea, help reduce inflammation.
  • Include high-fibre-containing foods, berries, cherries, leafy green veggies and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut and kimchi contain probiotics that help prevent excess stomach acid production.
  • Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

NON-STEROIDAL DRUG

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Esonap Tablet contains Naproxen (NSAID or pain reliever) and esomeprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Esomeprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps reduce the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

You are not recommended to take Esonap Tablet with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache. If you are supposed to use these medicines together, you are advised to contact your doctor to adjust the dose appropriately to use safely.

Yes, Esonap Tablet can alter specific medical tests like neuroendocrine tumors (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test, contact your doctor.

Naproxen in Esonap Tablet may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Esonap Tablet . However, it is recommended to take Esonap Tablet in the dose and for the duration as prescribed by your doctor. It should be not used by the patient who had recent heart bypass surgery (coronary artery bypass graft - CABG).

Esonap Tablet does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness. Arthritis is a chronic condition of joints with pain and inflammation.

Esonap Tablet is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of an egg from the ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping Esonap Tablet . However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking Esonap Tablet .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • WARFARIN
  • RIVAROXABAN
  • PREDNISOLONE
  • FUROSEMIDE
  • PROPRANOLOL
  • ENALAPRIL
  • LOSARTAN
  • CANDESARTAN
  • CITALOPRAM
  • METHOTREXATE

Special Advise

  • If you are elderly, a smoker who had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor, as these conditions may increase the risk of heart problems.
  • Your doctor may monitor liver and kidney function if you take Esonap Tablet for the long-term.
  • Individuals at risk for osteoporosis-related fractures should receive adequate calcium and vitamin D intake.
  • Esomeprazole in Esonap Tablet  may interfere with specific laboratory tests (including urine test for tetrahydrocannabinol-THC, a blood test to find certain tumours), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using Esonap Tablet .
  • Regular monitoring of vitamin B-12, rarely, esomeprazole in Esonap Tablet has chased vitamin B-12 deficiency. The risk increases if they take Esonap Tablet every day for a long time.

Disease/Condition Glossary

Osteoarthritis: Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age. The older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, dislocated joints, and ligaments. 

Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other body parts. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture, pain, and the back and joints.

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