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ESPRA XN TABLET contains Naproxen (NSAID or pain reliever) and esomeprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Esomeprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps reduce the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
You are not recommended to take ESPRA XN TABLET with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache. If you are supposed to use these medicines together, you are advised to contact your doctor to adjust the dose appropriately to use safely.
Yes, ESPRA XN TABLET can alter specific medical tests like neuroendocrine tumors (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test, contact your doctor.
Naproxen in ESPRA XN TABLET may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking ESPRA XN TABLET. However, it is recommended to take ESPRA XN TABLET in the dose and for the duration as prescribed by your doctor. It should be not used by the patient who had recent heart bypass surgery (coronary artery bypass graft - CABG).
ESPRA XN TABLET does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness. Arthritis is a chronic condition of joints with pain and inflammation.
ESPRA XN TABLET is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of an egg from the ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping ESPRA XN TABLET. However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking ESPRA XN TABLET.
Alcohol
Unsafe
You are recommended to avoid alcohol consumption with ESPRA XN TABLET as it may increase the risk of stomach bleeding and ulcer.
Pregnancy
Caution
There is limited data on how ESPRA XN TABLET affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting ESPRA XN TABLET.
Breast Feeding
Caution
ESPRA XN TABLET passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of ESPRA XN TABLET. Your doctor will weigh the benefits and any potential risks before prescribing ESPRA XN TABLET to you.
Driving
Caution
ESPRA XN TABLET may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking ESPRA XN TABLET.
Liver
Caution
ESPRA XN TABLET is to be used with caution in people having liver diseases. Dose adjustments may be necessary. So, you should use it only with your doctor's prescription.
Kidney
Caution
ESPRA XN TABLET is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.
Children
Caution
ESPRA XN TABLET should be used in children below 12 years of age only when prescribed by a child specialist.
Product Substitutes
About ESPRA XN TABLET
ESPRA XN TABLET belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers used to reduce and relieve pain. Pain is a highly unpleasant physical sensation caused by illness or injury.
ESPRA XN TABLET combines Naproxen (painkiller) and esomeprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, combined with esomeprazole (proton pump inhibitors), it reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
Take ESPRA XN TABLET as prescribed by your doctor. You are advised to take ESPRA XN TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea. Most of these side effects of ESPRA XN TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking this medicine, inform your doctor if you have any known allergy to Naproxen, esomeprazole, other NSAIDs, or other medications. If pregnant or breastfeeding, please inform your doctor before taking the ESPRA XN TABLET. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use ESPRA XN TABLET only when prescribed by a doctor. Keep your doctor informed about your health condition and all the medicines you take before taking ESPRA XN TABLET to rule out any side effects.
Uses of ESPRA XN TABLET
Medicinal Benefits
ESPRA XN TABLET contains Naproxen and esomeprazole (antacid). Naproxen is an anti-inflammatory (reduces inflammation) and an analgesic (relieves pain) agent that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. It also treats fibrositis (muscle pain and stiffness), tenosynovitis (swelling of tendons), low back pain, strains, and sprains. NSAIDs such as Naproxen have been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. To reduce gastric discomfort and stomach ulceration risk, it is combined with esomeprazole (a proton pump inhibitor that inhibits gastric acid secretion) to reduce stomach acid production during long-term treatment for people with pre-existing stomach ulcers or for people having a history of developing stomach ulcers while using NSAIDs. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
Directions for Use
Side Effects of ESPRA XN TABLET
Drug Warnings
Do not take ESPRA XN TABLET if you are allergic to ESPRA XN TABLET. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin), such as naproxen, may increase the risk of heart attack, stroke, and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, are older, are alcoholics, or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems, so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. ESPRA XN TABLET is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking ESPRA XN TABLET. ESPRA XN TABLET should not be given to children unless prescribed by a doctor. Do not take any other NSAIDs for pain relief along with ESPRA XN TABLET unless prescribed. Prolonged proton pump inhibitors like esomeprazole may cause brittle bones, so your doctor may recommend taking Vitamin D and calcium while using ESPRA XN TABLET. Do not consume alcohol with ESPRA XN TABLET as it may increase the risk of stomach bleeding or ulcer.
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