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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Nasal

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - EZI0016

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About Ezicas Nasal Spray 12 ml

Uses of Ezicas Nasal Spray 12 ml

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Ezicas Nasal Spray 12 ml

Drug Warnings

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Ezicas Nasal Spray 12 ml with Mifepristone may make Ezicas Nasal Spray 12 ml less effective as a therapy.

How to manage the interaction:
Taking Ezicas Nasal Spray 12 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Atazanavir and Ezicas Nasal Spray 12 ml may significantly increase the absorption of Ezicas Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Co-administration of Atazanavir and Ezicas Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneBoceprevir
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Boceprevir with Ezicas Nasal Spray 12 ml may significantly increase the absorption of Ezicas Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Co-administration of Boceprevir and Ezicas Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneTroleandomycin
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Troleandomycin may significantly increase the absorption of Ezicas Nasal Spray 12 ml and tend to increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ezicas Nasal Spray 12 ml and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
FluticasoneDinutuximab
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Dinutuximab and Ezicas Nasal Spray 12 ml may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Ezicas Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Ketoconazole and Ezicas Nasal Spray 12 ml may significantly increase the absorption of Ezicas Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
If you are supposed to take Ezicas Nasal Spray 12 ml and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneNefazodone
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Nefazodone may significantly increase the absorption of Ezicas Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Co-administration of Ezicas Nasal Spray 12 ml with Nefazodone can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Ezicas Nasal Spray 12 ml with posaconazole may increase the level of Ezicas Nasal Spray 12 ml in the blood and increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Ezicas Nasal Spray 12 ml and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
Co-administration of Mibefradil may significantly increase the absorption of Ezicas Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Taking Ezicas Nasal Spray 12 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneConivaptan
Severe
How does the drug interact with Ezicas Nasal Spray 12 ml:
When Conivaptan is taken with Ezicas Nasal Spray 12 ml, it can make Conivaptan break down faster in the body.

How to manage the interaction:
Co-administration of Conivaptan and Ezicas Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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FLUTICASONE PROPIONATE-0.05%W/VOther diseases of liver
Moderate
FLUTICASONE PROPIONATE-0.05%W/VCushing syndrome
Moderate

Drug-Diseases Interactions

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FLUTICASONE PROPIONATE-0.05%W/VOther diseases of liver
Moderate
How does the disease interact with Ezicas Nasal Spray 12 ml:
Corticosteroids are primarily eliminated by hepatic metabolism, hence liver dysfunction may cause them to accumulate. Hepatic disease patients need to be closely watched.

How to manage the interaction:
Liver disease patients using Ezicas Nasal Spray 12 ml should be monitored closely.
FLUTICASONE PROPIONATE-0.05%W/VCushing syndrome
Moderate
How does the disease interact with Ezicas Nasal Spray 12 ml:
Rarely, the use of nasal and inhaled corticosteroids may cause hyperadrenocorticism or worsen its symptoms. Corticosteroid side effects can be lessened by administering them locally rather than systemically, although the dangers are still present. Drugs that are applied topically or inhaled may enter the bloodstream, especially when high concentrations are utilised. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded. During inhaled or nasal corticosteroid medication, the emergence of symptoms such irregular menstruation, acneiform lesions, cataracts, and cushingoid features may signify overuse.

How to manage the interaction:
The use of inhaled and nasal corticosteroids such as Ezicas Nasal Spray 12 ml may rarely precipitate or aggravate conditions of hyperadrenocorticism. Hence, you are advised not to use more than the recommended dosages.
FLUTICASONE PROPIONATE-0.05%W/VGlaucoma
Moderate
How does the disease interact with Ezicas Nasal Spray 12 ml:
In patients with ocular herpes simplex, pharmacologic doses of corticosteroids may raise the risk of corneal perforation. In such patients, corticosteroid therapy should be delivered with caution, both orally and inhalation.

How to manage the interaction:
Inhaled and nasal Ezicas Nasal Spray 12 ml should be used with caution in patients with ocular herpes simplex (a type of viral eye infection).
FLUTICASONE PROPIONATE-0.05%W/VOsteoporosis without pathological fracture
Moderate
How does the disease interact with Ezicas Nasal Spray 12 ml:
Long-term inhalation of corticosteroids may cause a decline in bone density. This effect, which has mostly been documented with high dosages (>= 800 mcg/day of beclomethasone or similar for >= 1 year), appears to be dose-related. Patients getting lesser dosages have also been shown to have lower levels of total body calcium. Patients with osteoporosis should be treated with inhaled and nasal corticosteroids over the long term with caution. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded.

How to manage the interaction:
Long-term therapy with inhaled and nasal corticosteroids should be used with caution in patients with osteoporosis. It is advised not to exceed more than the recommended dosages.

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