CLOMIPHENE-100MGOther abnormal uterine and vaginal bleeding
How does the disease interact with Ferticleft 100mg Capsule:
Abnormal uterine bleeding:
In patients who are not diagnosed with abnormal genital bleeding, Ferticleft 100mg Capsule is contraindicated. Evaluate the patients for the presence of neoplastic lesions.
How to manage the interaction:
The use of Ferticleft 100mg Capsule is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIPHENE-100MGHepatic failure, not elsewhere classified
How does the disease interact with Ferticleft 100mg Capsule:
Hepatic dysfunction:
Ferticleft 100mg Capsule is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Ferticleft 100mg Capsule is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Ferticleft 100mg Capsule.
How to manage the interaction:
The use of Ferticleft 100mg Capsule is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIPHENE-100MGDisorders of endocrine glands in diseases classified elsewhere
How does the disease interact with Ferticleft 100mg Capsule:
Pituitary activity:
Ferticleft 100mg Capsule is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Ferticleft 100mg Capsule interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.
How to manage the interaction:
Ferticleft 100mg Capsule is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIPHENE-100MGOther disorders of adrenal gland
How does the disease interact with Ferticleft 100mg Capsule:
Uncontrolled adrenal dysfunction :
Ferticleft 100mg Capsule is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Ferticleft 100mg Capsule therapy may cause changes in steroid production and/or fluid balance.
How to manage the interaction:
The use of Ferticleft 100mg Capsule is contraindicated in patients with uncontrolled adrenal function.
CLOMIPHENE-100MGDisorders of lipoprotein metabolism and other lipidaemias
How does the disease interact with Ferticleft 100mg Capsule:
Hyperlipidemia:
Some patients who are on Ferticleft 100mg Capsule therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Ferticleft 100mg Capsule for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Ferticleft 100mg Capsule.
How to manage the interaction:
Hypertriglyceridemia may occur during Ferticleft 100mg Capsule therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Ferticleft 100mg Capsule therapy.