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Alcohol
Caution
It is not known if alcohol affects Fitoxim 1500 Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.
Pregnancy
Caution
Please consult the doctor as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Fitoxim 1500 Injection.
Driving
Caution
Fitoxim 1500 Injection may cause dizziness. Drive or operate machinery only if you are alert.
Liver
Caution
Limited information is available regarding the use of Fitoxim 1500 Injection in patients suffering from liver impairment. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
Dose adjustment may be needed. Please consult your doctor if you have kidney problems.
Children
Safe if prescribed
Fitoxim 1500 Injection can be given safely to children provided a child specialist has prescribed the dose.
Product Substitutes
Drug-Drug Interactions
CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe
Drug-Drug Interactions
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CefuroximeBCG vaccine
Severe
How does the drug interact with Fitoxim 1500 Injection:
Co-administration of Fitoxim 1500 Injection may reduce the anti-tumor activity of BCG in the bladder.
How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Fitoxim 1500 Injection. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Fitoxim 1500 Injection may reduce the anti-tumor activity of BCG in the bladder.
How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Fitoxim 1500 Injection. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Fitoxim 1500 Injection:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Fitoxim 1500 Injection.
How to manage the interaction:
Although taking Fitoxim 1500 Injection and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Fitoxim 1500 Injection.
How to manage the interaction:
Although taking Fitoxim 1500 Injection and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Fitoxim 1500 Injection:
Co-administration of Dalteparin and Fitoxim 1500 Injection can increase the blood levels and effects of Dlateparin.
How to manage the interaction:
Taking Fitoxim 1500 Injection with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Dalteparin and Fitoxim 1500 Injection can increase the blood levels and effects of Dlateparin.
How to manage the interaction:
Taking Fitoxim 1500 Injection with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Moderate
How does the drug interact with Fitoxim 1500 Injection:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.
How to manage the interaction:
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Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.
How to manage the interaction:
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Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CEFUROXIME-1500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-1500MGChronic kidney disease
Moderate
Drug-Diseases Interactions
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CEFUROXIME-1500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Fitoxim 1500 Injection:
Colitis: In some cases the use of Fitoxim 1500 Injection may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.
How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Fitoxim 1500 Injection should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
Colitis: In some cases the use of Fitoxim 1500 Injection may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.
How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Fitoxim 1500 Injection should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-1500MGChronic kidney disease
Moderate
How does the disease interact with Fitoxim 1500 Injection:
Renal dysfunction: Fitoxim 1500 Injection is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Fitoxim 1500 Injection as necessary.
How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
Renal dysfunction: Fitoxim 1500 Injection is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Fitoxim 1500 Injection as necessary.
How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-1500MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Fitoxim 1500 Injection:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Fitoxim 1500 Injection after dialysis or an additional dosage to be administered.
How to manage the interaction:
Fitoxim 1500 Injection serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Fitoxim 1500 Injection after dialysis or an additional dosage to be administered.
How to manage the interaction:
Fitoxim 1500 Injection serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-1500MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Fitoxim 1500 Injection:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Fitoxim 1500 Injection if seizures are reported.
How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Fitoxim 1500 Injection should be discontinued if seizures associated with drug therapy occur.
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Fitoxim 1500 Injection if seizures are reported.
How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Fitoxim 1500 Injection should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-1500MGOther diseases of liver
Moderate
How does the disease interact with Fitoxim 1500 Injection:
liver disease: With Fitoxim 1500 Injection, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.
How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
liver disease: With Fitoxim 1500 Injection, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.
How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-1500MGOther diseases of liver
Moderate
How does the disease interact with Fitoxim 1500 Injection:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.
How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.
How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.
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