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  3. Gemfrac Combipack Injection 1's (3 Cartridges+1 Pen)

Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma

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Whats That

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

BONE ENHANCERS

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - GEM0391

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Gemfrac Combipack Injection 1's (3 Cartridges+1 contains Teriparatide is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.

Gemfrac Combipack Injection 1's (3 Cartridges+1 can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Gemfrac Combipack Injection 1's (3 Cartridges+1 as a daily supplement if you have any kidney problems or a history of kidney stones.

Persons whose age is more than 35 years have low estrogen levels, female reaching menopause, too much consumption of alcohol, tobacco, or caffeine, use of glucocorticoid and lack of calcium and vitamin D in the foods are some of the factors that can increase the risk of osteoporosis.

Gemfrac Combipack Injection 1's (3 Cartridges+1 is a part of a complete program that includes modifications in diet, regular exercise, bone mineral density testing and intake of calcium and vitamin supplements. Follow all the guidelines given by the doctor very closely.

Yes, Gemfrac Combipack Injection 1's (3 Cartridges+1 may increase serum calcium, urinary calcium, and serum uric acid. Inform the person doing the tests that you are taking Gemfrac Combipack Injection 1's (3 Cartridges+1 .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Gemfrac Combipack Injection 1's (3 Cartridges+1 . Alcohol intake, along with Gemfrac Combipack Injection 1's (3 Cartridges+1 , may cause increased drowsiness.

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Pregnancy

Caution

It is advised not to take Gemfrac Combipack Injection 1's (3 Cartridges+1 if you are pregnant unless prescribed by the doctor as Gemfrac Combipack Injection 1's (3 Cartridges+1 is a pregnancy category C drug. Your doctor will prescribe Gemfrac Combipack Injection 1's (3 Cartridges+1 only if the benefits outweigh the risks.

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Breast Feeding

Caution

It isn’t known if Gemfrac Combipack Injection 1's (3 Cartridges+1 passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.

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Driving

Caution

It may cause dizziness, fatigue and blurring of vision; do not drive or operate heavy machinery if you feel drowsy.

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Liver

Caution

Dose adjustment may be needed. Gemfrac Combipack Injection 1's (3 Cartridges+1 should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Tell your doctor if you have kidney disorders as after checking the health condition, a doctor will decide that this medicine is safe to prescribe or not.

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Children

Caution

Gemfrac Combipack Injection 1's (3 Cartridges+1 should not be given to children or adolescents whose age is less than 18 years. Safety and effectiveness have not been established.

About Gemfrac Combipack Injection 1's (3 Cartridges+1

Gemfrac Combipack Injection 1's (3 Cartridges+1 belongs to the class of medication called 'anabolic (promoting bone formation) agent' indicated for prevention and treatment of osteoporosis in adults and helps to strengthen the bone. This medicine also helps to reduce the risk of spine and hip fractures. Osteoporosis is a medical condition in which bone becomes thin or weak. The chance of developing osteoporosis increases with age, after menopause or by taking corticosteroid medications (such as prednisone) for a long period. If proper treatment is not provided then it can even result in broken bones.

Gemfrac Combipack Injection 1's (3 Cartridges+1 contains Teriparatide a synthetic form of the human parathyroid hormone, which helps to regulate calcium metabolism. Gemfrac Combipack Injection 1's (3 Cartridges+1 works by causing the body to build new bone by increasing bone strength and bone mass density (BMD) (thickness) and reduce the risk of fractures by stimulating bone formation. It also increases the thickness of bone and rebuilds bones which reduces the risk of spine and hip fractures.

Gemfrac Combipack Injection 1's (3 Cartridges+1 will be administered by a healthcare professional; do not self-administer. In some cases, Gemfrac Combipack Injection 1's (3 Cartridges+1 can cause side effects like nausea, vomiting,  joint pain, leg cramps, swelling/redness at the injection site, upset stomach, diarrhea, constipation, runny nose, cough, and throat irritation. Most of these side effects of Gemfrac Combipack Injection 1's (3 Cartridges+1 do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

To treat your condition effectually, continue taking Gemfrac Combipack Injection 1's (3 Cartridges+1 for as long as your doctor has prescribed. Consult your doctor before taking Gemfrac Combipack Injection 1's (3 Cartridges+1 if you are pregnant or breastfeeding; your doctor will prescribe you Gemfrac Combipack Injection 1's (3 Cartridges+1 only if the benefits outweigh the risks. Gemfrac Combipack Injection 1's (3 Cartridges+1 is not recommended for children below 18 years of age.  Tell your doctor that you are taking Gemfrac Combipack Injection 1's (3 Cartridges+1 before you have any lab test as this medicine could interfere with the results. Gemfrac Combipack Injection 1's (3 Cartridges+1 may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Inform your doctor about your health condition and medications before taking Gemfrac Combipack Injection 1's (3 Cartridges+1 to rule out any side effects. Gemfrac Combipack Injection 1's (3 Cartridges+1 is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might be lost. Do not store in the freezer or the fridge.

Uses of Gemfrac Combipack Injection 1's (3 Cartridges+1

Osteoporosis, Postmenopausal osteoporosis

Medicinal Benefits Mweb

Medicinal Benefits

Gemfrac Combipack Injection 1's (3 Cartridges+1 is a synthetic form of a natural human hormone called parathyroid hormone (PTH) that is prescribed to prevent and treat osteoporosis in persons with weak bones. It prevents the loss of bones that happens after menopause and helps to rebuild bones. Gemfrac Combipack Injection 1's (3 Cartridges+1 contains Teriparatide which works by causing the body to build new bone and by increasing bone strength and bone mass density (BMD) (thickness) and reduce the risk of fractures by stimulating bone formation. It also increases the thickness of bone and rebuilds bones which reduces the risk of spine and hip fractures. Gemfrac Combipack Injection 1's (3 Cartridges+1 is also indicated for the treatment of increasing bone mass in people with osteoporosis, glucocorticoid-induced osteoporosis.

Directions for Use

Gemfrac Combipack Injection 1's (3 Cartridges+1 will be administered by a healthcare professional; do not self-administer.

Side Effects of Gemfrac Combipack Injection 1's (3 Cartridges+1

  • Nausea
  • Vomiting
  • Joint pain,
  • Leg cramps
  • Swelling/redness at the injection site
  • Feeling dizzy, tired, or weak
  • Upset stomach
  • Diarrhea 
  • Constipation
  • Runny nose
  • Cough
  • Throat irritation

Drug Warnings

Gemfrac Combipack Injection 1's (3 Cartridges+1 is not recommended if you have hypercalcemia (high calcium levels) or an overactive parathyroid gland, metastatic calcification (extra deposits of calcium in the body) and malabsorption syndrome (difficulty absorbing nutrition from food), kidney stones, kidney problems (moderate renal impairment), Paget’s disease of bone (abnormal bone changes), history of skeletal malignancies. It is important that your doctor check your progress regularly to make sure that Gemfrac Combipack Injection 1's (3 Cartridges+1 is working properly. Blood and urine tests may be needed to check for unwanted effects. Gemfrac Combipack Injection 1's (3 Cartridges+1 can increase the amount of calcium in your blood or urine. Talk to your doctor before or while using Gemfrac Combipack Injection 1's (3 Cartridges+1 if you have continuing nausea, vomiting, constipation, low energy or muscle weakness. These may be signs there is too much calcium in your blood. Consult your doctor before taking Gemfrac Combipack Injection 1's (3 Cartridges+1 if you are pregnant or breastfeeding; your doctor will prescribe you Gemfrac Combipack Injection 1's (3 Cartridges+1 only if the benefits outweigh the risks. Gemfrac Combipack Injection 1's (3 Cartridges+1 should not be given to children as safety and efficacy have not been established. Do not take Gemfrac Combipack Injection 1's (3 Cartridges+1 for longer durations unless prescribed by your doctor. If your condition does not improve even after taking the Gemfrac Combipack Injection 1's (3 Cartridges+1 full course, please consult your doctor.  Gemfrac Combipack Injection 1's (3 Cartridges+1 may increase the risk of having cancer while taking longer durations. Talk to your doctor if you have concerns about this risk. Avoid consuming alcohol along with Gemfrac Combipack Injection 1's (3 Cartridges+1 as it could lead to increased drowsiness. Inform your doctor about your health condition and medications before taking Gemfrac Combipack Injection 1's (3 Cartridges+1 to rule out any side effects.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • DIGITALIS
  • CALCITRIOL
  • CALCIPOTRIENE
  • FUROSEMIDE
  • HYDROCHLOROTHIAZIDE

Habit Forming

No

Special Advise

  • Certain diagnostic test like blood test measures the level of calcitonin in your blood and bone density scan is used to check bone mineral density (BMD).
  • Gemfrac Combipack Injection 1's (3 Cartridges+1 should not be prescribed for patients at increased baseline risk of osteosarcoma (bone cancer).
  • Clinical monitoring of urine tests or serum electrolyte concentrations is recommended.
  • Do not take Gemfrac Combipack Injection 1's (3 Cartridges+1 for longer durations unless prescribed by your doctor.

Diet & Lifestyle Advise

  • A person should consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • A post-menopausal woman should limit salt intake as it can pose a high risk of losing more bone minerals than other women of the same age.
  • Do regular exercise like weight-bearing exercises which are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps to ensure the absorption and retention of calcium in bones, so take food high in calcium and vitamins.

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