Gercillin 500 Injection

How does the drug interact with Gercillin 500 Injection:
When BCG vaccine is used with Gercillin 500 Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Gercillin 500 Injection with BCG vaccine can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.

How does the drug interact with Gercillin 500 Injection:
Co-administration of Methotrexate with Gercillin 500 Injection can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Gercillin 500 Injection, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.

How does the drug interact with Gercillin 500 Injection:
Co-administration of Gercillin 500 Injection with Cholera, live attenuated together may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Gercillin 500 Injection or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.

How does the disease interact with Gercillin 500 Injection:
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame.

How to manage the interaction:
Gercillin 500 Injection should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation in the large intestine) and pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps and sometimes associated with the passage of blood and mucus).

How does the disease interact with Gercillin 500 Injection:
When given an aminopenicillin antibiotic for mononucleosis, patients may experience a pruritic, erythematous, maculopapular skin rash. Usually, the rash self-limits and goes away a few days after the offending chemical is stopped. The underlying mechanism has been suggested to be a changed drug metabolism or an immune-mediated process unrelated to drug hypersensitivity. Patients with mononucleosis shouldn't receive treatment with antibiotics containing aminopenicillin.

How to manage the interaction:
Gercillin 500 Injection should not be used in patients with mononucleosis (contagious infection caused by virus) as it may cause skin rash.

How does the disease interact with Gercillin 500 Injection:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in some situations, as metabolites as well. In individuals with reduced renal function, the serum concentrations of beta-lactam antibiotics and their metabolites may rise, and their half-lives may be prolonged. These individuals have had parenteral administration of these drugs and have experienced neurotoxic responses such as encephalopathy, asterixis, myoclonus, seizures, and coma. Adjustments to the dosage may be required.

How to manage the interaction:
Dose adjustments may be required in patients with kidney impairment. Kidney function tests should be performed at regular intervals during prolonged and/or high-dose therapy since nephrotoxicity (rapid deterioration in kidney function) and alterations in kidney function have occasionally been associated with the use of Gercillin 500 Injection.