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  1. Home
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  3. Gestobond 400 Softgel Capsule 10's

Gestobond 400 Softgel Capsule 10's, Pack of 10
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
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COD available

Online payment accepted

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Whats That

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Composition :

PROGESTERONE-400MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

VAGINAL

Return Policy :

Not Returnable

Therapeutic Class

HORMONES

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India).
Other Info - GES0139

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

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FAQs

Gestobond 400 Softgel Capsule 10's causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps to maintain pregnancy.

Do not use Gestobond 400 Softgel Capsule 10's if you are allergic to any of its components or if you have/had porphyria, breast or genital cancer, abnormal vaginal bleeding due to miscarriage or missed abortion, blood clots or stroke, liver disease or abnormal liver tests.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high estrogen levels, and women can have decreased sex drive, weight gain or gallbladder problems.

Gestobond 400 Softgel Capsule 10's may cause vaginal spotting, vaginal irritation, or application site reactions. Consult your doctor if the condition persists or worsens.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol affects Gestobond 400 Softgel Capsule 10's. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Contact the doctor before using Gestobond 400 Softgel Capsule 10's. Your doctor will decide whether Gestobond 400 Softgel Capsule 10's should be used by the pregnant woman or not depending on her condition.

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Breast Feeding

Unsafe

The use of Gestobond 400 Softgel Capsule 10's during breastfeeding is not recommended.

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Driving

Caution

Gestobond 400 Softgel Capsule 10's does not influence the ability to drive and use machines.

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Liver

Unsafe

Do not use Gestobond 400 Softgel Capsule 10's if you have/had liver disease or abnormal liver tests.

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Kidney

Caution

Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Gestobond 400 Softgel Capsule 10's is not recommended for use in children or adolescents.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1283.pdf
  2. https://www.medicines.org.uk/emc/product/1283/smpc
  3. https://www.medsafe.govt.nz/Consumers/cmi/c/crinone.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020701s026lbl.pdf

About Gestobond 400 Softgel Capsule 10's

Gestobond 400 Softgel Capsule 10's belongs to the class of medicines known as hormones used to treat female infertility and to aid pregnancy. It is also used to restore the menstrual cycle in women who have missed their periods. Female infertility is a condition in which a female body is unable to conceive despite regular, unprotected sexual intercourse for at least one year.

Gestobond 400 Softgel Capsule 10's contains progesterone, a female hormone that regulates ovulation and menstruation in women. Gestobond 400 Softgel Capsule 10's induces secretory changes in the endometrium lining of the uterus, relaxes the uterus, blocks the maturation and release of follicles and maintains pregnancy.

Use Gestobond 400 Softgel Capsule 10's as directed by your doctor. It is intended for intra-vaginal use only. In some cases, Gestobond 400 Softgel Capsule 10's may cause abdominal pain, headache, constipation, nausea, and breast pain/enlargement. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using Gestobond 400 Softgel Capsule 10's inform your doctor if you have/had liver or kidney problems, heart problems, diabetes, asthma, epilepsy, migraine or depression. Let your doctor know if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and all the medicines you are taking to rule out any side effects/interactions. Avoid smoking and alcohol consumption.

Uses of Gestobond 400 Softgel Capsule 10's

Female Infertility

Medicinal Benefits Mweb

Medicinal Benefits

Gestobond 400 Softgel Capsule 10's contains progesterone, which helps ovulation and menstruation. Gestobond 400 Softgel Capsule 10's causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps to maintain pregnancy.

Directions for Use

Vaginal spray: Check the label for directions before using the spray. Shake well before each use. Spray the contents from a 5cm distance on the affected area.Vaginal gel: Apply the gel into the vagina using the applicator.

Side Effects of Gestobond 400 Softgel Capsule 10's

  • Abdominal pain
  • Headache
  • Constipation
  • Nausea
  • Breast pain/enlargement.

Drug Warnings

Do not use Gestobond 400 Softgel Capsule 10's if you are allergic to any of its components, or if you have unexplained vaginal bleeding, porphyria, cancer, thrombophlebitis and missed abortion or miscarriage. Keep your doctor informed about your health condition and all the medicines you are taking before taking Gestobond 400 Softgel Capsule 10's to rule out any side effects/interactions. Gestobond 400 Softgel Capsule 10's is not recommended for children. 

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
ProgesteroneMorphine
Severe

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
When Gestobond 400 Softgel Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Gestobond 400 Softgel Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneMorphine
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
Co-administration of Gestobond 400 Softgel Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Gestobond 400 Softgel Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneVenetoclax
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
Co-administration of Gestobond 400 Softgel Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Gestobond 400 Softgel Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneTirzepatide
Moderate
How does the drug interact with Gestobond 400 Softgel Capsule:
Gestobond 400 Softgel Capsule may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Before taking this medication, your doctor will do a smear test and examine your breasts and pelvic area.
  • Your doctor will look for any womb issues during your treatment, such as the thickening of the endometrial lining (endometrial hyperplasia). 
  • They will also examine your blood vessels for symptoms of blood clots.

Diet & Lifestyle Advise

  • It is critical to lose weight and maintain a healthy BMI in order to boost fertility.
  • Caffeine and caffeinated drinks should be avoided for improved fertility.
  • Reduce your carbohydrate intake and eat more antioxidant-rich foods.
  • Include beans, lentils, Greek yoghurt, cheese, probiotics, and vitamin D as they aid in ovulation.
  • Asparagus should be included in your everyday diet. Asparagus is a superfood that has amazing benefits for women attempting to conceive.
  • Quit smoking.
  • Avoid consumption of alcohol.

Gestobond 400 Softgel Capsule 10's Substitute

Substitutes safety advice

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