Gluvilda-M 1000 Tablet is a combination drug of Vildagliptin (DPP-4 inhibitor) and Metformin (Biguanides) belongs to the class of anti-diabetic. Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity-onset diabetes. Type 2 diabetes develops if the body does not produce enough insulin or when your body's insulin does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals. Gluvilda-M 1000 Tablet is another substance which triggers the production of sugar by the liver, causing the blood sugar to rise. The pancreas makes both of these substances.

Gluvilda-M 1000 Tablet helps to control the blood sugar level. It works by making the pancreas produce insulin and less glucagon (effect of vildagliptin) and also by helping the body to make better use of the insulin it has (effect of metformin). You must continue following the diet and exercise recommended for you whilst on treatment with Gluvilda-M 1000 Tablet . Gluvilda-M 1000 Tablet is not a substitute for insulin. It is not used to treat type 1 diabetes (where your body does not produce insulin) or diabetic ketoacidosis.

Gluvilda-M 1000 Tablet should be taken with food to avoid an upset stomach. Gluvilda-M 1000 Tablet should be taken at the same time of the day each time for best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Gluvilda-M 1000 Tablet is hypoglycemia (low blood glucose levels) characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Gluvilda-M 1000 Tablet should not be stopped even if you feel better without consulting your doctor as sugar levels change. If you stop taking Gluvilda-M 1000 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Gluvilda-M 1000 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeed.

Gluvilda-M 1000 Tablet helps your pancreas produce more insulin, effectively utilise insulin, and decrease the excess sugar that your liver makes. It helps control the rise of blood sugar levels in your body after a meal. Gluvilda-M 1000 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

Gluvilda-M 1000 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Gluvilda-M 1000 Tablet , might develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood that can damage the working of your liver and kidney required for the elimination of excess lactic acid from the blood. Before you start taking Gluvilda-M 1000 Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 level. Gluvilda-M 1000 Tablet , when used with insulin, may extremely lower the blood sugar level leading to hypoglycaemia condition, which can be fatal. In this case, your doctor may adjust the dose by lowering the dose of insulin or Gluvilda-M 1000 Tablet . Prolonged intake of Gluvilda-M 1000 Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. The use of Gluvilda-M 1000 Tablet should be stopped for a short time before having an X-ray procedure.

Contact your doctor immediately if you have nausea, vomiting, kussmaul breathing  (laboured and deep), and generalised weakness which are symptoms of Lactic acidosis, a very rare but serious metabolic complication.