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Prescription drugWhats That
Composition :
GENTAMICIN-40MG
Manufacturer/Marketer :
Biochem Pharmaceutical Industries Ltd
Consume Type :
PARENTERAL
Return Policy :
Not Returnable
Expires on or after :
Secure Payment
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Alcohol
Caution
Limit or avoid alcohol intake while being treated with Gracin 40 mg Injection 2 ml since it may worsen side effects like dizziness.
Pregnancy
Caution
Gracin 40 mg Injection 2 ml should be cautiously administered during pregnancy since there are chances of fetal harm. Please consult your doctor before taking Gracin 40 mg Injection 2 ml if you are pregnant or planning to conceive.
Breast Feeding
Caution
Gracin 40 mg Injection 2 ml can be excreted into breast milk in small amounts when used by a nursing mother. Please consult your doctor before taking Gracin 40 mg Injection 2 ml if you are breastfeeding.
Driving
Caution
Gracin 40 mg Injection 2 ml may cause side effects like dizziness or vertigo that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.
Liver
Caution
Let your doctor know if you have any history of liver diseases before taking Gracin 40 mg Injection 2 ml since it may cause abnormal liver function tests.
Kidney
Caution
Let your doctor know if you have any history of kidney diseases or impairment before taking Gracin 40 mg Injection 2 ml. Dose adjustment may be required.
Children
Caution
Gracin 40 mg Injection 2 ml should be used for children only when prescribed by a doctor. The dose may depend on the child's age and body weight.
Product Substitutes
coupon
Drug-Drug Interactions
GentamicinBotulinum toxin
Severe
GentamicinMagnesium sulfate
Severe
Drug-Drug Interactions
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GentamicinBotulinum toxin
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Using Gracin 40 mg Injection 2 ml with Botulinum toxin can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Botulinum toxin and Gracin 40 mg Injection 2 ml, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
Using Gracin 40 mg Injection 2 ml with Botulinum toxin can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Botulinum toxin and Gracin 40 mg Injection 2 ml, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
GentamicinMagnesium sulfate
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Magnesium sulfate with Gracin 40 mg Injection 2 ml can increase the risk of muscle weakness.
How to manage the interaction:
Although there is a possible interaction between Magnesium sulfate and Gracin 40 mg Injection 2 ml, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness and breathing difficulties. Do not stop using any medications without talking to a doctor.
Co-administration of Magnesium sulfate with Gracin 40 mg Injection 2 ml can increase the risk of muscle weakness.
How to manage the interaction:
Although there is a possible interaction between Magnesium sulfate and Gracin 40 mg Injection 2 ml, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness and breathing difficulties. Do not stop using any medications without talking to a doctor.
GentamicinColistin
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Colistin with Gracin 40 mg Injection 2 ml can increase the levels and risk of Colistin side effects.
How to manage the interaction:
Although there is a possible interaction between Colistin and Gracin 40 mg Injection 2 ml, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of Colistin with Gracin 40 mg Injection 2 ml can increase the levels and risk of Colistin side effects.
How to manage the interaction:
Although there is a possible interaction between Colistin and Gracin 40 mg Injection 2 ml, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
GentamicinIopamidol
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Iopamidol with Gracin 40 mg Injection 2 ml may increase the risk of kidney problems.
How to manage the interaction:
Co-administration of Gracin 40 mg Injection 2 ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.
Co-administration of Iopamidol with Gracin 40 mg Injection 2 ml may increase the risk of kidney problems.
How to manage the interaction:
Co-administration of Gracin 40 mg Injection 2 ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.
GentamicinBumetanide
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Taking Gracin 40 mg Injection 2 ml can cause hearing loss, ringing in the ears, vertigo, and kidney problems, and combining it with bumetanide may increase the risk.
How to manage the interaction:
Although there is a possible interaction, Gracin 40 mg Injection 2 ml can be taken with bumetanide if prescribed by the doctor. Consult the doctor if you experience hearing loss, ringing in the ears, vertigo, or kidney problems.
Taking Gracin 40 mg Injection 2 ml can cause hearing loss, ringing in the ears, vertigo, and kidney problems, and combining it with bumetanide may increase the risk.
How to manage the interaction:
Although there is a possible interaction, Gracin 40 mg Injection 2 ml can be taken with bumetanide if prescribed by the doctor. Consult the doctor if you experience hearing loss, ringing in the ears, vertigo, or kidney problems.
GentamicinPipecuronium bromide
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Pipecuronium bromide with Gracin 40 mg Injection 2 ml may increase the risk or severity of side effects.
How to manage the interaction:
There may be a possibility of interaction between Gracin 40 mg Injection 2 ml and Pipecuronium bromide, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact your doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without a doctor's advice.
Co-administration of Pipecuronium bromide with Gracin 40 mg Injection 2 ml may increase the risk or severity of side effects.
How to manage the interaction:
There may be a possibility of interaction between Gracin 40 mg Injection 2 ml and Pipecuronium bromide, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact your doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without a doctor's advice.
GentamicinMivacurium chloride
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Mivacurium with Gracin 40 mg Injection 2 ml can make it more effective as a therapy.
How to manage the interaction:
Taking Gracin 40 mg Injection 2 ml with Mivacurium chloride together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without talking to a doctor.
Co-administration of Mivacurium with Gracin 40 mg Injection 2 ml can make it more effective as a therapy.
How to manage the interaction:
Taking Gracin 40 mg Injection 2 ml with Mivacurium chloride together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without talking to a doctor.
GentamicinTemsirolimus
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Gracin 40 mg Injection 2 ml and Temsirolimus may increase the risk of kidney problems.
How to manage the interaction:
Co-administration of Gracin 40 mg Injection 2 ml with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
Co-administration of Gracin 40 mg Injection 2 ml and Temsirolimus may increase the risk of kidney problems.
How to manage the interaction:
Co-administration of Gracin 40 mg Injection 2 ml with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
GentamicinDoxacurium chloride
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
Co-administration of Doxacurium with Gracin 40 mg Injection 2 ml may increase the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Gracin 40 mg Injection 2 ml and Doxacurium chloride, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not discontinue any medications without consulting a doctor.
Co-administration of Doxacurium with Gracin 40 mg Injection 2 ml may increase the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Gracin 40 mg Injection 2 ml and Doxacurium chloride, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not discontinue any medications without consulting a doctor.
GentamicinRocuronium bromide
Severe
How does the drug interact with Gracin 40 mg Injection 2 ml:
When Rocuronium is used with Gracin 40 mg Injection 2 ml, it can make the treatment more effective.
How to manage the interaction:
Co-administration of Rocuronium bromide with Gracin 40 mg Injection 2 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
When Rocuronium is used with Gracin 40 mg Injection 2 ml, it can make the treatment more effective.
How to manage the interaction:
Co-administration of Rocuronium bromide with Gracin 40 mg Injection 2 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
GENTAMICIN-40MGOther symptoms and signs involving the digestive system and abdomen
Severe
GENTAMICIN-40MGMyasthenia gravis and other myoneural disorders
Severe
Drug-Diseases Interactions
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GENTAMICIN-40MGOther symptoms and signs involving the digestive system and abdomen
Severe
How does the disease interact with Gracin 40 mg Injection 2 ml:
Adequate hydration is critical for reducing the risk of oto- and nephrotoxicity associated with aminoglycoside usage. Dehydration should preferably be treated before starting therapy. Fluid status should be continuously maintained in patients who are at risk of dehydration, such as those who have severe and/or prolonged diarrhoea or vomiting. If indications of renal irritation appear during therapy, hydration should be increased as directed, followed by a dose reduction if necessary. If urine flow gradually decreases or azotemia worsens, therapy should be discontinued.
How to manage the interaction:
Dehydration should be corrected prior to initiation of therapy. Fluid status should be monitored closely in patients who may be at risk for dehydration, such as those with severe and/or prolonged diarrhea or vomiting. Therapy should be withdrawn if urinary output decreases progressively or azotemia (elevated levels of urea) increases.
Adequate hydration is critical for reducing the risk of oto- and nephrotoxicity associated with aminoglycoside usage. Dehydration should preferably be treated before starting therapy. Fluid status should be continuously maintained in patients who are at risk of dehydration, such as those who have severe and/or prolonged diarrhoea or vomiting. If indications of renal irritation appear during therapy, hydration should be increased as directed, followed by a dose reduction if necessary. If urine flow gradually decreases or azotemia worsens, therapy should be discontinued.
How to manage the interaction:
Dehydration should be corrected prior to initiation of therapy. Fluid status should be monitored closely in patients who may be at risk for dehydration, such as those with severe and/or prolonged diarrhea or vomiting. Therapy should be withdrawn if urinary output decreases progressively or azotemia (elevated levels of urea) increases.
GENTAMICIN-40MGMyasthenia gravis and other myoneural disorders
Severe
How does the disease interact with Gracin 40 mg Injection 2 ml:
Aminoglycosides can elicit dose-related neuromuscular blockade and muscle weakness, especially in patients with neuromuscular illness or hypocalcemia, as well as in those undergoing general anaesthesia, neuromuscular blocking medications, or substantial transfusions of citrate-anticoagulated blood. Although neuromuscular blockade caused by aminoglycosides is usually self-limiting, it can occasionally result in respiratory paralysis. The most potent neuromuscular blocking drug in the class is regarded to be neomycin. However, the risk is greatest with large dosages instilled intraperitoneally or intrapleurally, or with fast intravenous administration of parenteral aminoglycosides. In patients with neuromuscular problems (e.g., myasthenia gravis, parkinsonian syndrome, botulism) or hypocalcemia, aminoglycoside therapy should be used with caution. If indications of respiratory paralysis appear during aminoglycoside therapy, the medicine should be stopped and, if necessary, mechanical breathing assistance administered.
How to manage the interaction:
Therapy should be administered cautiously in patients with neuromuscular disorders (e.g., myasthenia gravis, Parkinsonian syndrome, botulism) or hypocalcemia (low calcium levels). The drug should be discontinued and mechanical respiratory assistance provided if needed if signs of respiratory paralysis occur during therapy.
Aminoglycosides can elicit dose-related neuromuscular blockade and muscle weakness, especially in patients with neuromuscular illness or hypocalcemia, as well as in those undergoing general anaesthesia, neuromuscular blocking medications, or substantial transfusions of citrate-anticoagulated blood. Although neuromuscular blockade caused by aminoglycosides is usually self-limiting, it can occasionally result in respiratory paralysis. The most potent neuromuscular blocking drug in the class is regarded to be neomycin. However, the risk is greatest with large dosages instilled intraperitoneally or intrapleurally, or with fast intravenous administration of parenteral aminoglycosides. In patients with neuromuscular problems (e.g., myasthenia gravis, parkinsonian syndrome, botulism) or hypocalcemia, aminoglycoside therapy should be used with caution. If indications of respiratory paralysis appear during aminoglycoside therapy, the medicine should be stopped and, if necessary, mechanical breathing assistance administered.
How to manage the interaction:
Therapy should be administered cautiously in patients with neuromuscular disorders (e.g., myasthenia gravis, Parkinsonian syndrome, botulism) or hypocalcemia (low calcium levels). The drug should be discontinued and mechanical respiratory assistance provided if needed if signs of respiratory paralysis occur during therapy.
GENTAMICIN-40MGOther disorders of ear, not elsewhere classified
Severe
How does the disease interact with Gracin 40 mg Injection 2 ml:
Aminoglycosides can harm the eighth cranial nerve, causing vestibular and/or auditory toxicity. Dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment are among the symptoms. Following the discontinuation of the medicine, permanent hearing loss, including whole or partial irreversible bilateral deafness, may occur. Therapy with aminoglycosides, especially if extended (> 10 days), should be used with caution in patients with preexisting vestibular and/or auditory impairment, as it may delay or obfuscate the diagnosis of a drug-induced ototoxic impact. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other ototoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels.
How to manage the interaction:
Therapy should be administered with caution in patients with ototoxicity. The dosage should be reduced or therapy shoule be withdrawn if signs and symptoms of toxicity develop.
Aminoglycosides can harm the eighth cranial nerve, causing vestibular and/or auditory toxicity. Dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment are among the symptoms. Following the discontinuation of the medicine, permanent hearing loss, including whole or partial irreversible bilateral deafness, may occur. Therapy with aminoglycosides, especially if extended (> 10 days), should be used with caution in patients with preexisting vestibular and/or auditory impairment, as it may delay or obfuscate the diagnosis of a drug-induced ototoxic impact. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other ototoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels.
How to manage the interaction:
Therapy should be administered with caution in patients with ototoxicity. The dosage should be reduced or therapy shoule be withdrawn if signs and symptoms of toxicity develop.
GENTAMICIN-40MGUnspecified kidney failure
Severe
How does the disease interact with Gracin 40 mg Injection 2 ml:
Aminoglycosides have the potential to be ototoxic and nephrotoxic. Damage to the eighth cranial nerve can cause vestibular and/or auditory toxicities such as dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment. Tubular necrosis, increases in BUN, nonprotein nitrogen, and serum creatinine concentration, decreases in urine specific gravity and creatinine clearance, proteinuria, and cells or casts in the urine are all signs of nephrotoxicity. Rarely, renal electrolyte wasting can cause hypocalcemia, hypomagnesemia, and hypokalemia, which can be accompanied with paresthesia, tetany, disorientation, and positive Chvostek and Trousseau symptoms. Although aminoglycoside-induced nephrotoxicity is often reversible after treatment withdrawal, mortality from uremia has happened on rare occasions. Patients with renal impairment should be treated with caution and at lower doses of aminoglycosides, as they may be at risk.Drug buildup increases the risk of oto- and nephrotoxicity. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other neuro- and nephrotoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels. If toxicity develops, renal and eighth cranial nerve function should be constantly monitored, and the dosage lowered or therapy discontinued.
How to manage the interaction:
Therapy should be administered cautiously at reduced dosages in patients with kidney impairment. Patients should be adequately hydrated, the dose should not be exceeded, and use with other neuro- and nephrotoxic agents should be avoided to minimize the risk of toxicity.
Aminoglycosides have the potential to be ototoxic and nephrotoxic. Damage to the eighth cranial nerve can cause vestibular and/or auditory toxicities such as dizziness, nystagmus, vertigo, ataxia, tinnitus, and varied degrees of hearing impairment. Tubular necrosis, increases in BUN, nonprotein nitrogen, and serum creatinine concentration, decreases in urine specific gravity and creatinine clearance, proteinuria, and cells or casts in the urine are all signs of nephrotoxicity. Rarely, renal electrolyte wasting can cause hypocalcemia, hypomagnesemia, and hypokalemia, which can be accompanied with paresthesia, tetany, disorientation, and positive Chvostek and Trousseau symptoms. Although aminoglycoside-induced nephrotoxicity is often reversible after treatment withdrawal, mortality from uremia has happened on rare occasions. Patients with renal impairment should be treated with caution and at lower doses of aminoglycosides, as they may be at risk.Drug buildup increases the risk of oto- and nephrotoxicity. Patients should be adequately hydrated, the usual aminoglycoside dosage should not be exceeded, use with other neuro- and nephrotoxic agents should be avoided, and peak and trough serum aminoglycoside concentrations should be determined on a regular basis and dosage adjusted to maintain desired levels. If toxicity develops, renal and eighth cranial nerve function should be constantly monitored, and the dosage lowered or therapy discontinued.
How to manage the interaction:
Therapy should be administered cautiously at reduced dosages in patients with kidney impairment. Patients should be adequately hydrated, the dose should not be exceeded, and use with other neuro- and nephrotoxic agents should be avoided to minimize the risk of toxicity.
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