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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

GRANISETRON-1MG

Manufacturer/Marketer :

Bennet Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIEMETICS

Country of origin

India

Manufacturer/Marketer address

608 B Wing, 6Th Floor, Manubhai Tower, Sayajigunj, Sayajigunj, Vadodara, Gujarat 390005
Other Info - GRA0406

Author Details

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FAQs

Granirex-1 Tablet contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granirex-1 Tablet relieves from post-operative nausea and vomiting symptoms.

Granirex-1 Tablet may cause constipation as one of its side effects. You can avoid it by including high fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.

Granirex-1 Tablet should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick or difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.

You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.

Take Granirex-1 Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Granirex-1 Tablet . Alcohol intake, along with Granirex-1 Tablet , may cause increased dizziness.

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Pregnancy

Caution

It is not known if Granirex-1 Tablet affects pregnancy. Please consult your doctor if you are pregnant or planning to conceive before using Granirex-1 Tablet .

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Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please consult your doctor before taking Granirex-1 Tablet if you are a nursing mother.

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Driving

Caution

Granirex-1 Tablet may make you feel dizzy that affects your mental ability. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Granirex-1 Tablet should be cautiously used by patients with liver diseases. Please consult your doctor if you have a history of liver impairment before starting Granirex-1 Tablet .

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Kidney

Caution

Granirex-1 Tablet should be cautiously used by patients with kidney problems. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Caution

Safety and efficacy of Granirex-1 Tablet are not established in children below 2 years of age.

About Granirex-1 Tablet

Granirex-1 Tablet belongs to the class of ‘anti-emetic’ drugs, primarily used to treat nausea and vomiting caused by medical treatments, such as chemotherapy or radiation treatment for cancer, etc. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Granirex-1 Tablet contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron' that belongs to the class of serotonin receptor antagonists or serotonin blockers. It works by blocking the activity of serotonin (chemical messenger) in the brain that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granirex-1 Tablet include diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, drowsiness, trouble sleeping , and anxiety. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Granirex-1 Tablet . Let your doctor know if you have any liver, kidney, or heart diseases, stomach/intestinal problems, allergic reactions , and low levels of potassium and magnesium in the blood before starting Granirex-1 Tablet . Granirex-1 Tablet may make you dizzy or drowsy, hence avoid driving if you are not mentally alert. Consult your doctor before taking Granirex-1 Tablet if you are pregnant, planning for pregnancy, or breastfeeding. Avoid consuming alcohol along with Granirex-1 Tablet as it could lead to increased drowsiness. 

Uses of Granirex-1 Tablet

Nausea and vomiting.

Medicinal Benefits Mweb

Medicinal Benefits

Granirex-1 Tablet contains an anti-emetic drug, 'Granisetron' that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery, etc. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Granirex-1 Tablet works by blocking the activity of serotonin in the brain and preventing post-operative nausea and vomiting.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water, do not chew, crush or break it.Syrup/Liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of Granirex-1 Tablet

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Anxiety

Drug Warnings

Granirex-1 Tablet may cause serotonin syndrome/toxicity when used with other drugs like ecstasy (MDMA) and antidepressants. Hence it is suggested to seek medical advice if you are using any prescription or non-prescription medicines. Inform your doctor if you have a history of stomach/intestinal problems like stomach ache, wind, feeling or being sick, and difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granirex-1 Tablet . Please consult your doctor if you are pregnant or breastfeeding if the doctor has advised you Granirex-1 Tablet . Granirex-1 Tablet may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol as it could lead to increased dizziness. Granirex-1 Tablet is not recommended in children below two years of age.

Drug-Drug Interactions

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GranisetronCisapride
Critical
GranisetronSparfloxacin
Critical

Drug-Drug Interactions

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GranisetronCisapride
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronSparfloxacin
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Sparfloxacin can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Sparfloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronSaquinavir
Critical
How does the drug interact with Granirex-1 Tablet:
When Granirex-1 Tablet is taken with Saquinavir, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronDronedarone
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronMesoridazine
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with mesoridazine can increase the risk of an irregular heart rhythm. I

How to manage the interaction:
Taking Mesoridazine with Granirex-1 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronPimozide
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Pimozide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronZiprasidone
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronThioridazine
Critical
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Thioridazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granirex-1 Tablet with Thioridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronRemifentanil
Severe
How does the drug interact with Granirex-1 Tablet:
Combining Granirex-1 Tablet with Remifentanil can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Co-administration of Granirex-1 Tablet with Remifentanil can possibly result in an interaction, but it can be taken if doctor has advised it. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, diarrhea, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GranisetronApomorphine
Severe
How does the drug interact with Granirex-1 Tablet:
Taking Granirex-1 Tablet with Apomorphine can increase the risk of low blood pressure.

How to manage the interaction:
Co-administration of Granirex-1 Tablet with Apomorphine can result in an interaction, but it can be taken if a doctor has advised it. If you are taking these medications together, it is important to be careful and watch out for low blood pressure. If you notice any symptoms like lightheadedness, loss of consciousness, chest discomfort or heaviness, or shaking movements, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LITHIUM
  • DULOXETINE
  • AMIODARONE
  • QUINIDINE
  • RITONAVIR
  • ERYTHROMYCIN

Habit Forming

No

Special Advise

Let your doctor know that you are taking Granirex-1 Tablet if you are undergoing any medical tests.

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol and smoking.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Granirex-1 Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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    9.45per tablet
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    24.42per tablet
  • Avogran 1mg Tablet DT

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    17.31per tablet

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