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Therapeutic Class

COUGH AND COLD PREPARATIONS

Country of origin

India

Manufacturer/Marketer address

Plot No 38, Mohan Nagar, Kuldeep Nagar, Ambala Cantt - 133004, Haryana, India
Other Info - GR49175

Author Details

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FAQs

Grankof D Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Consult your doctor before taking Grankof D Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Grankof D Syrup 72 hours prior to the surgery.

It is not recommended to take Grankof D Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Grankof D Syrup should be taken at least 14 days after the last dose of anti-depressants.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the scheduled dose. Do not take extra medicine to make up for the missed dose.

Grankof D Syrup may rarely worsen the symptoms of glaucoma. Therefore, Grankof D Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.

Disclaimer

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Alcohol

Caution

Avoid consumption of alcohol with Grankof D Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Grankof D Syrup.

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Pregnancy

Caution

The safety of Grankof D Syrup in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Grankof D Syrup is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if Grankof D Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Grankof D Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Grankof D Syrup.

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Liver

Caution

Take Grankof D Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Grankof D Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Grankof D Syrup is not recommended for children below 12 years of age. However, please consult a doctor if you have any concerns.

About Grankof D Syrup

Grankof D Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum.

Grankof D Syrup contains Chlorpheniramine maleate, Phenylephrine and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Grankof D Syrup helps provide relief from dry cough.

Your doctor will recommend the dose and duration of Grankof D Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. Most of these side effects of Grankof D Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or breastfeeding. Grankof D Syrup is not recommended for children below 12 years of age. If you are about to undergo medical tests or surgery, please inform your doctor that you are taking Grankof D Syrup. Grankof D Syrup may cause dizziness, so drive or operate machinery only if you are alert. Avoid alcohol consumption as it may cause increased dizziness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Grankof D Syrup

Dry cough

Medicinal Benefits Mweb

Medicinal Benefits

Grankof D Syrup is a combination medicine belonging to a class of drugs called 'cough and cold preparations' primarily used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine is a decongestant that helps shrink the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Grankof D Syrup helps relieve cough, cold and allergic symptoms.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of Grankof D Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

If you are allergic to Grankof D Syrup or any other medicines, please tell your doctor. Consult your doctor if you are pregnant or breastfeeding. Grankof D Syrup is not recommended for children below 12 years of age. Avoid taking Grankof D Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor if you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions

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DextromethorphanIsocarboxazid
Critical

Drug-Drug Interactions

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How does the drug interact with Grankof D Syrup:
Co-administration of Grankof D Syrup and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Grankof D Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Grankof D Syrup:
Co-administration of Isocarboxazid with Grankof D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Grankof D Syrup and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Grankof D Syrup:
Taking Rasagiline with Grankof D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Grankof D Syrup with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Grankof D Syrup:
Co-administration of Phenelzine and Grankof D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Grankof D Syrup can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Grankof D Syrup:
Taking Tranylcypromine with Grankof D Syrup can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Grankof D Syrup with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Grankof D Syrup:
Co-administration of Pargyline and Grankof D Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Grankof D Syrup and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Grankof D Syrup:
Co-administration of Grankof D Syrup and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Grankof D Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grankof D Syrup:
Taking Furazolidone with Grankof D Syrup can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Grankof D Syrup is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Grankof D Syrup only after 14 days of stopping Furazolidone.
How does the drug interact with Grankof D Syrup:
Co-administration of Selegiline with Grankof D Syrup together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Grankof D Syrup is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Grankof D Syrup:
Taking Tranylcypromine with Grankof D Syrup can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Grankof D Syrup is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ASPIRIN
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE

Habit Forming

No

Special Advise

  • Talk to your doctor if your symptoms do not improve even after taking Grankof D Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash or headache after taking Grankof D Syrup. 
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Grankof D Syrup.

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

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