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Prescription drugWhats That
Composition :
CLOMIPHENE-50MG + MELATONIN-3MG
Manufacturer/Marketer :
Xeno Pharmaceuticals
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Secure Payment
Trusted by 8 Crore Indians
Genuine Products
Author Details
_0.jpg?tr=q-80,f-webp,w-100,dpr-6,c-at_max "Santoshini Reddy G")
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Alcohol
Consult your doctor
It is not known if alcohol affects Greatova 50 Tablet. Please consult your doctor.
Pregnancy
Caution
Greatova 50 Tablet must not be used in pregnancy. In case of pregnancy, stop using this drug. Tell your doctor straight away if you suspect being pregnant.
Breast Feeding
Consult your doctor
Limited information is available. Please consult your doctor if you are breastfeeding.
Driving
Caution
Greatova 50 Tablet may cause blurred vision. Drive or operate machinery only if you are alert.
Liver
Consult your doctor
Please inform your doctor before taking this medicine if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Please inform your doctor before taking this medicine if you have kidney impairment or any concerns regarding this.
Children
Not applicable
This medicine is used in women to treat infertility.
Product Substitutes
Drug-Drug Interactions
clomipheneOspemifene
Critical
clomipheneFluoroestradiol (18f)
Severe
Drug-Drug Interactions
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clomipheneOspemifene
Critical
How does the drug interact with Greatova 50 Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.
How to manage the interaction:
Taking Greatova 50 Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.
How to manage the interaction:
Taking Greatova 50 Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Greatova 50 Tablet:
Co-administration of Fluoroestradiol F 18 together with Greatova 50 Tablet may reduce the action of Fluoroestradiol F 18.
How to manage the interaction:
Taking Greatova 50 Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
Co-administration of Fluoroestradiol F 18 together with Greatova 50 Tablet may reduce the action of Fluoroestradiol F 18.
How to manage the interaction:
Taking Greatova 50 Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
clomipheneBexarotene
Severe
How does the drug interact with Greatova 50 Tablet:
Co-administration of Greatova 50 Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.
How to manage the interaction:
Although there is an interaction, Greatova 50 Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
Co-administration of Greatova 50 Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.
How to manage the interaction:
Although there is an interaction, Greatova 50 Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CLOMIPHENE-50MG+MELATONIN-3MGOther abnormal uterine and vaginal bleeding
Severe
CLOMIPHENE-50MG+MELATONIN-3MGHepatic failure, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLOMIPHENE-50MG+MELATONIN-3MGOther abnormal uterine and vaginal bleeding
Severe
How does the disease interact with Greatova 50 Tablet:
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Greatova 50 Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Greatova 50 Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIPHENE-50MG+MELATONIN-3MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Greatova 50 Tablet:
Hepatic dysfunction: Greatova 50 Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Greatova 50 Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Greatova 50 Tablet.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
Hepatic dysfunction: Greatova 50 Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Greatova 50 Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Greatova 50 Tablet.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIPHENE-50MG+MELATONIN-3MGDisorders of endocrine glands in diseases classified elsewhere
Severe
How does the disease interact with Greatova 50 Tablet:
Pituitary activity: Greatova 50 Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Greatova 50 Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.
How to manage the interaction:
Greatova 50 Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
Pituitary activity: Greatova 50 Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Greatova 50 Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.
How to manage the interaction:
Greatova 50 Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIPHENE-50MG+MELATONIN-3MGOther disorders of adrenal gland
Severe
How does the disease interact with Greatova 50 Tablet:
Uncontrolled adrenal dysfunction : Greatova 50 Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Greatova 50 Tablet therapy may cause changes in steroid production and/or fluid balance.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with uncontrolled adrenal function.
Uncontrolled adrenal dysfunction : Greatova 50 Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Greatova 50 Tablet therapy may cause changes in steroid production and/or fluid balance.
How to manage the interaction:
The use of Greatova 50 Tablet is contraindicated in patients with uncontrolled adrenal function.
CLOMIPHENE-50MG+MELATONIN-3MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with Greatova 50 Tablet:
Hyperlipidemia: Some patients who are on Greatova 50 Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Greatova 50 Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Greatova 50 Tablet.
How to manage the interaction:
Hypertriglyceridemia may occur during Greatova 50 Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Greatova 50 Tablet therapy.
Hyperlipidemia: Some patients who are on Greatova 50 Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Greatova 50 Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Greatova 50 Tablet.
How to manage the interaction:
Hypertriglyceridemia may occur during Greatova 50 Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Greatova 50 Tablet therapy.
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