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Drug-Drug Interactions Checker List

  • TRIAMTERENE
  • SPIRONOLACTONE
  • AMILORIDE

Drug-Drug Interactions

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Potassium citrateOrphenadrine (chloride)
Critical
Potassium citrateTrihexyphenidyl
Critical

Drug-Drug Interactions

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Potassium citrateOrphenadrine (chloride)
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Orphenadrine and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (chloride) with Gushout Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateTrihexyphenidyl
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Co-administration of trihexyphenidyl with Gushout Oral Solution 450 ml may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Gushout Oral Solution 450 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium citrateFlavoxate
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Flavoxate and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Flavoxate with Gushout Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOxybutynin
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Coadministration of Oxybutynin and Gushout Oral Solution 450 ml can increase the risk of developing stomach ulcers or bleeding.

How to manage the interaction:
Taking Oxybutynin with Gushout Oral Solution 450 ml is generally avoided as it may lead to an interaction, it can be taken if prescribed by the doctor. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medications without a doctor's advice.
Potassium citrateCyproheptadine
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Cyproheptadine and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Cyproheptadine with Gushout Oral Solution 450 ml is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOlanzapine
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Olanzapine with Gushout Oral Solution 450 ml can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Olanzapine and Gushout Oral Solution 450 ml is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium citrateClozapine
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Clozapine and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Gushout Oral Solution 450 ml with Clozapine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateScopolamine
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Scopolamine and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Gushout Oral Solution 450 ml and Scopolamine is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateDoxepin
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Doxepin and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Doxepin with Gushout Oral Solution 450 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, consult the doctor immediately if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools. Do not discontinue any medications without a doctor's advice.
Potassium citrateImipramine
Critical
How does the drug interact with Gushout Oral Solution 450 ml:
Taking Imipramine and Gushout Oral Solution 450 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Gushout Oral Solution 450 ml and Imipramine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

Do not take Gushout Oral Solution 450 ml if you are allergic to any of its contents; if you have hyperkalaemia (high levels of potassium), chronic renal failure, uncontrolled diabetes mellitus, adrenal insufficiency, acute dehydration, oesophageal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency. Inform your doctor if you have hyperkalaemia or gastrointestinal lesions. If you experience severe vomiting, gastrointestinal bleeding or abdominal pain, stop taking Gushout Oral Solution 450 ml and consult a doctor immediately. Gushout Oral Solution 450 ml is not recommended for children as safety and effectiveness have not been established. Consult your doctor if you are pregnant or breastfeeding. 

Side Effects of Gushout Oral Solution 450 ml

  • Abdominal discomfort
  • Diarrhoea
  • Vomiting
  • Nausea

Directions for Use

Tablet: Swallow it as a whole with water; do not crush or chew the tablet.Syrup/suspension/solution/liquid: The prescribed dose should be diluted with a glass of water and taken or as advised by the doctor.

Medicinal Benefits Mweb

Medicinal Benefits

Gushout Oral Solution 450 ml is a combination of three drugs, namely: Magnesium citrate, Potassium citrate, and Pyridoxine. Gushout Oral Solution 450 ml is indicated for the treatment of renal tubular acidosis, kidney stones, and prevents recurrence of calcium oxalate nephrolithiasis (calcium oxalate stones) and uric acid lithiasis (uric acid stones) with or without calcium stones. It also helps provide relief from burning sensation during urination. Gushout Oral Solution 450 ml raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts. 

Uses of Gushout Oral Solution 450 ml

Kidney stones, renal tubular acidosis.

About Gushout Oral Solution 450 ml

Gushout Oral Solution 450 ml is indicated for the treatment of renal tubular acidosis and kidney stones. It also helps provide relief from burning sensation during urination. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine, this causes the blood to remain too acidic.
 
Gushout Oral Solution 450 ml is a combination of three drugs, namely: Magnesium citrate, Potassium citrate, and Pyridoxine. Gushout Oral Solution 450 ml raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts.
 
You are advised to take Gushout Oral Solution 450 ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. Gushout Oral Solution 450 ml is not recommended for children as safety and effectiveness have not been established. Gushout Oral Solution 450 ml is not recommended for patients with renal insufficiency as it might increase the risk of developing hyperkalaemia (high potassium levels) and soft tissue calcification. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Side Effects of Gushout Oral Solution 450 ml

  • Abdominal discomfort
  • Diarrhoea
  • Vomiting
  • Nausea
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Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Therapeutic Class

RENAL AND GENITOURINARY AGENT

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