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  3. Hepagrit-25000 Injection 5 ml

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Whats That

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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Integrity Pharmaceutical Corp

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Country of origin

India

Manufacturer/Marketer address

1172, Opposite Railway Station, Nr By Bajwa Railway Crossing Line, Bajwa, Vadodara
Other Info - HEP0387

Author Details

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FAQs

No, you are not recommended to take ibuprofen with Hepagrit-25000 Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hepagrit-25000 Injection 5 ml.

Yes, Hepagrit-25000 Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Hepagrit-25000 Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Hepagrit-25000 Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hepagrit-25000 Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Disclaimer

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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hepagrit-25000 Injection 5 ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hepagrit-25000 Injection 5 ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hepagrit-25000 Injection 5 ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hepagrit-25000 Injection 5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hepagrit-25000 Injection 5 ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hepagrit-25000 Injection 5 ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hepagrit-25000 Injection 5 ml is not recommended for children below 2 months.

About Hepagrit-25000 Injection 5 ml

Hepagrit-25000 Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hepagrit-25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Hepagrit-25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hepagrit-25000 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hepagrit-25000 Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Hepagrit-25000 Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hepagrit-25000 Injection 5 ml. Hepagrit-25000 Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hepagrit-25000 Injection 5 ml.

Uses of Hepagrit-25000 Injection 5 ml

Prevention of blood clots.

Medicinal Benefits Mweb

Medicinal Benefits

Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hepagrit-25000 Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Hepagrit-25000 Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Directions for Use

Hepagrit-25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Side Effects of Hepagrit-25000 Injection 5 ml

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

Drug Warnings

Use Hepagrit-25000 Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hepagrit-25000 Injection 5 ml. Patients should inform the doctor that they are receiving Hepagrit-25000 Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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HeparinOritavancin
Critical

Drug-Drug Interactions

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How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Alteplase with Hepagrit-25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepagrit-25000 Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Using Hepagrit-25000 Injection 5 ml with Oritavancin can make Hepagrit-25000 Injection 5 ml less effective as a therapy.

How to manage the interaction:
Hepagrit-25000 Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hepagrit-25000 Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hepagrit-25000 Injection 5 ml:
When Hepagrit-25000 Injection 5 ml is taken with bazedoxifene the effects of Hepagrit-25000 Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hepagrit-25000 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Ticlopidine with Hepagrit-25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hepagrit-25000 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Tenecteplase with Hepagrit-25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepagrit-25000 Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Mifepristone with Hepagrit-25000 Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Hepagrit-25000 Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinDicoumarol
Severe
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Coadministration of Hepagrit-25000 Injection 5 ml and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Hepagrit-25000 Injection 5 ml and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Bivalirudin with Hepagrit-25000 Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Although taking Bivalirudin and Hepagrit-25000 Injection 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Dasatinib with Hepagrit-25000 Injection 5 ml can increase the risk and severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Hepagrit-25000 Injection 5 ml and Dasatinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepagrit-25000 Injection 5 ml:
Taking Hepagrit-25000 Injection 5 ml with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Although taking Hepagrit-25000 Injection 5 ml and Streptokinase together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Hepagrit-25000 Injection 5 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Hepagrit-25000 Injection 5 ml.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Habit Forming

No

Special Advise

Regular blood tests are advised while taking Hepagrit-25000 Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

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