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  1. Home
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  3. Hervycta 440Mg Inj

Hervycta 440Mg Inj, Pack of 1 Injection
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

TRASTUZUMAB-440MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Hervycta 440Mg Inj

Hervycta 440Mg Inj is an anti-cancer medicine used in the treatment of HER2-positive Breast cancer and HER2-positive metastatic gastric or gastroesophageal junction adenocarcinoma. Cancer is a disease where the cells grow abnormally and divide uncontrollably. It can also be used when the cancer has spread to other parts of the body.

Hervycta 440Mg Inj contains Trastuzumab as an active ingredient, which belongs to the class of monoclonal antibodies. It works by inhibiting the abnormal growth of cancer cells and, finally, causes the initiation of programmed cell death.

Hervycta 440Mg Inj may cause certain side effects such as abdominal pain, chills, diarrhoea, fatigue, nausea, back pain, bone pain, edema, insomnia, fever, dizziness, headache, vomiting, cough, rash, and injection site reactions. If the side effects persist or bother you, please consult your doctor. Hervycta 440Mg Inj will be administered by a trained doctor. Hence, do not self-administer.

Avoid taking it and inform your doctor if you are allergic to Hervycta 440Mg Inj or its components. Inform your doctor if you have any cardiovascular conditions, lung problems, or liver/kidney disease, as it can cause adverse effects. Hervycta 440Mg Inj is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Hervycta 440Mg Inj

Breast Cancer, Stomach Cancer.

Directions for Use

A doctor who is trained or experienced in the administration of chemotherapeutic agents will administer Hervycta 440Mg Inj. Do not self-administer.

Medicinal Benefits

Hervycta 440Mg Inj contains Trastuzumab, which is used for treating patients with HER2-positive breast cancer and HER2-positive metastatic gastroesophageal adenocarcinoma. This medicine works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of programmed cell death.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Hervycta 440Mg Inj should be avoided if you are allergic to it or any other components of this medicine. Inform your doctor if you have any lung problems, cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Hervycta 440Mg Inj may cause left ventricular ejection fraction, cardiomyopathy, pulmonary toxicity, exacerbations of chemotherapy-induced neutropenia, and hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. Hervycta 440Mg Inj may cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Hervycta 440Mg Inj is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

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TrastuzumabBaricitinib
Severe
TrastuzumabThalidomide
Severe

Drug-Drug Interactions

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TrastuzumabBaricitinib
Severe
How does the drug interact with Hervycta 440Mg Inj:
Coadministration of Hervycta 440Mg Inj with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Hervycta 440Mg Inj and Baricitinib, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
TrastuzumabThalidomide
Severe
How does the drug interact with Hervycta 440Mg Inj:
Taking thalidomide together with Hervycta 440Mg Inj may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Hervycta 440Mg Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
TrastuzumabEtanercept
Severe
How does the drug interact with Hervycta 440Mg Inj:
When Etanercept is used with Hervycta 440Mg Inj, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Hervycta 440Mg Inj and Etanercept, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
TrastuzumabInfliximab
Severe
How does the drug interact with Hervycta 440Mg Inj:
Combining Hervycta 440Mg Inj with Infliximab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Hervycta 440Mg Inj with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrastuzumabClozapine
Severe
How does the drug interact with Hervycta 440Mg Inj:
Co-administration of Hervycta 440Mg Inj and clozapine can increase the risk of toxicity.

How to manage the interaction:
Although taking Hervycta 440Mg Inj and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not stop using any medications without first talking to your doctor.
TrastuzumabCladribine
Severe
How does the drug interact with Hervycta 440Mg Inj:
Combining Hervycta 440Mg Inj with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Hervycta 440Mg Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
TrastuzumabIdarubicin
Severe
How does the drug interact with Hervycta 440Mg Inj:
Taking Hervycta 440Mg Inj with Idarubicin can increase the risk of heart problems.

How to manage the interaction:
Co-administration of Hervycta 440Mg Inj with Idarubicin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience difficulty breathing, fluid retention, or chest pain, consult a doctor. Do not discontinue any medications without a doctor's advice.
TrastuzumabTofacitinib
Severe
How does the drug interact with Hervycta 440Mg Inj:
Combining Hervycta 440Mg Inj with Tofacitinib can increase the risk of neutropenia.

How to manage the interaction:
Although there is a possible interaction between Hervycta 440Mg Inj and Tofacitinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Hervycta 440Mg Inj Substitute

Substitutes safety advice

Product Substitutes

Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Hervycta 440Mg Inj contains Trastuzumab, which works by inhibiting the excess production of a protein called human epidermal growth factor receptor 2 (HER2) in mammalian cells. This causes inhibition of the cancer cell growth.

Inform your doctor whether you have received any other cancer treatment. Hervycta 440Mg Inj may cause a decrease in left ventricular ejection fraction, cardiomyopathy, hypersensitivity reactions, pulmonary toxicity, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, lung problems, are pregnant, are planning to become pregnant, or are breastfeeding before receiving Hervycta 440Mg Inj.

Drug-Drug Interactions Checker List

  • ETANERCEPT
  • NATALIZUMAB
  • INDINAVIR
  • EFAVIRENZ
  • ATAZANAVIR
  • GOLIMUMAB

Special Advise

  • Avoid intercourse while on treatment with Hervycta 440Mg Inj.
  • Regular, complete blood count monitoring is advised during the treatment.
  • All patients should be tested for HER2 test before starting the treatment regimen.
  • Liver function tests (LFT) and pulmonary function tests (PFT) should be performed before starting the treatment and every 4 to 6 weeks during the treatment.
  • Regular ECG and electrolytes should be monitored while taking the medicine.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Stomach Cancer (Gastric adenocarcinoma): It is a type of cancer that develops from the stomach lining. When the cancer cells spread to other organs of the body, it is called metastatic. This condition can occur mainly due to smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.

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